Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Masako Kajihara"'
Autor:
Toshihiko Sugie, Keiji Fujioka, Masako Kajihara, Masao Tanihara, Yosuke Urabe, Yukio Imanishi, Akihiko Sano
Publikováno v:
Chemical and Pharmaceutical Bulletin. 51:11-14
Silicone has been utilized as a carrier material for sustained release system of lipophilic drugs. Extensive studies revealed that drug release rate is influenced by factors such as physicochemical properties of the drug and additives.(1-5)) When a l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52f03883969500c5f994f96230ab5a7
https://doi.org/10.1248/cpb.51.11
https://doi.org/10.1248/cpb.51.11
Publikováno v:
Journal of Controlled Release. 77:261-272
Collagen films containing human growth hormone (hGH) were prepared and the release of hGH from these films and their effect on healing of full-thickness wounds in db/db mice were evaluated. The release profiles of hGH from the collagen films varied w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f366fba0bf061ab4927680ca279774d
https://doi.org/10.1016/s0168-3659(01)00512-0
https://doi.org/10.1016/s0168-3659(01)00512-0
Publikováno v:
Drug Delivery System. 14:381-385
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61347eae8f2e8962e50bb6cd0102328c
https://doi.org/10.2745/dds.14.381
https://doi.org/10.2745/dds.14.381
Autor:
Toshihiko Sugie, Akihiko Sano, Keiji Fujioka, Masao Tanihara, Masako Kajihara, Yukio Imanishi, Hiroo Maeda, Yosuke Urabe
Publikováno v:
Chemicalpharmaceutical bulletin. 51(1)
Drug release mechanism from silicone carrier differs depending on physicochemical properties of the drug. So far, there have been few reports on controlled release of insoluble drug and on simultaneous release of two kinds of water-soluble drugs. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea6c55397faf3a3a1584f2a79276464
https://pubmed.ncbi.nlm.nih.gov/12520121
https://pubmed.ncbi.nlm.nih.gov/12520121
Autor:
Keiji Fujioka, Toshihiko Sugie, Takami Hojo, Hiroo Maeda, Yosuke Urabe, Shuichi Sugawara, Masako Kajihara, Akihiko Sano
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 73(2-3)
In order to achieve a zero-order release of protein drugs, we have developed a new drug delivery system using silicone, which is named the covered-rod-type formulation. Preparation of the covered-rod-type formulation was conducted under mild conditio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::910b23de45a7dd28d306d05c9b60d3e4
https://pubmed.ncbi.nlm.nih.gov/11516505
https://pubmed.ncbi.nlm.nih.gov/11516505
Autor:
Masako Kajihara, Toshihiko Sugie, Masayuki Mizuno, Nobuhiko Tamura, Akihiko Sano, Keiji Fujioka, Yasuo Kashiwazaki, Takashi Yamaoka, Shuichi Sugawara, Yosuke Urabe
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 66(1)
A novel technique, by which protein drugs effective in small doses can be released over a long period, was developed using silicone and a water-soluble substance. In this study, interferon (IFN) was used as a model of the protein drugs. The IFN-silic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c66eff1e93c47d2ebe54844fdc018fa
https://pubmed.ncbi.nlm.nih.gov/10708878
https://pubmed.ncbi.nlm.nih.gov/10708878
Publikováno v:
Journal of biomedical materials research. 25(11)
Materials to enhance cell adhesion were synthesized by surface integration of peptide, Arg-Gly-Asp-Ser(RGDS), which is an active-site sequence of cell-adhesive proteins. Polystyrene film was glow-discharged and graft-copolymerized with acrylic acid.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a76dcac209ad6bab3c97f589d97f74ab
https://pubmed.ncbi.nlm.nih.gov/1797805
https://pubmed.ncbi.nlm.nih.gov/1797805
Publikováno v:
Journal of Macromolecular Science: Part A - Chemistry. 25:555-570
For one of the approaches to antithrombogenic materials, the combination of synthetic polymers with physiologically active substances seems to be promising. One of these ways involves crosslinked urokinase (HM-UK), in which urokinases are linked with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fabac37e4964c366c9c208e7085e6aa
https://doi.org/10.1080/00222338808053384
https://doi.org/10.1080/00222338808053384