Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Masako Asahina"'
Autor:
Jordan D Ward, Nagagireesh Bojanala, Teresita Bernal, Kaveh Ashrafi, Masako Asahina, Keith R Yamamoto
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1003992 (2013)
Individual metazoan transcription factors (TFs) regulate distinct sets of genes depending on cell type and developmental or physiological context. The precise mechanisms by which regulatory information from ligands, genomic sequence elements, co-fact
Externí odkaz:
https://doaj.org/article/e23799e7bdcc4b0bb8069f74d19ba603
Autor:
Lucie Panska, Stepanka Nedvedova, Vojtech Vacek, Daniela Krivska, Lukas Konecny, Filip Knop, Zsofia Kutil, Lubica Skultetyova, Adrian Leontovyc, Lenka Ulrychova, Judy Sakanari, Masako Asahina, Cyril Barinka, Marie Macurkova, Jan Dvorak
Human glutamate carboxypeptidase 2 (GCP2) from the M28B metalloprotease group is an important target for therapy in neurological disorders and an established tumor marker. However, its physiological functions remain unclear. To better understand gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b1731fc7498e4a448fa3fc1551d34dc
https://doi.org/10.1101/2023.02.27.529682
https://doi.org/10.1101/2023.02.27.529682
Autor:
Masako Asahina, Keith R. Yamamoto, Kirk T. Ehmsen, Matthew T. Knuesel, Haruna Aridomi, Delsy M. Martinez
Publikováno v:
Nucleic acids research, vol 49, iss 16
Nucleic Acids Research
Nucleic Acids Research
Unequivocal functional assessment of candidate genomic regulatory regions, such as transcriptional response elements, requires genetic alteration at their native chromosomal loci. Targeted DNA cleavage by Cas9 or other programmable nucleases enables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4189f06ba74f86edb9e7040c49ea6acf
https://escholarship.org/uc/item/78m2g8wd
https://escholarship.org/uc/item/78m2g8wd
Metazoan transcriptional regulatory factors (TFs) bind to genomic response elements and assemble with co-regulators into transcriptional regulatory complexes (TRCs) whose composition, structure and activities are gene-, cell- and physiological-contex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6dc5e78b8a82ca992d50fa2b77afcc
Autor:
Ryusuke Niwa, Masako Asahina, Hiroshi Hasegawa, Frank J. Slack, Yasunori Kanaho, Kazumasa Hada
Publikováno v:
Developmental Biology. 344(2):1100-1109
Developmental timing in the nematode Caenorhabditis elegans is controlled by heterochronic genes, mutations in which cause changes in the relative timing of developmental events. One of the heterochronic genes, let-7, encodes a microRNA that is highl
Publikováno v:
Developmental Cell. 11:203-211
beta-Catenin signaling determines the proximal-distal axis of the C. elegans gonad by promoting distal fate in asymmetrically dividing somatic gonad precursor cells (SGPs). Impaired function of the Wnt effector POP-1/TCF, its coactivator SYS-1/beta-c
Autor:
Motoko Shionoya, Masako Asahina, Lynn M. Riddiford, Shinji Nagata, Hisato Kuniyoshi, Hiroshi Kataoka, Hideki Matsubayashi
Publikováno v:
Insect Biochemistry and Molecular Biology. 33:795-801
A cDNA encoding a putative precursor of prothoracicotropic hormone (PTTH) from the tobacco hornworm, Manduca sexta, was isolated and sequenced. This clone contains an open reading frame encoding a 226-amino acid prepropeptide hormone. The deduced ami
Publikováno v:
Worm, vol 3, iss 2
Ward, J; Yamamoto, K; & Asahina, M. (2014). SUMO as a nuclear hormone receptor effector: New insights into combinatorial transcriptional regulation.. Worm. UC Santa Cruz: Retrieved from: http://www.escholarship.org/uc/item/35t6n3xz
Ward, J; Yamamoto, K; & Asahina, M. (2014). SUMO as a nuclear hormone receptor effector: New insights into combinatorial transcriptional regulation.. Worm. UC Santa Cruz: Retrieved from: http://www.escholarship.org/uc/item/35t6n3xz
Animal development is driven by robust, cell-specific gene expression programs. Understanding mechanistically how a single transcription factor (TF) can govern distinct programs with exquisite precision is a major challenge. We view TFs as signal int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c1122e20897c454cd6ac2fc74accc1
https://europepmc.org/articles/PMC4165532/
https://europepmc.org/articles/PMC4165532/
Autor:
Masako Asahina, Jordan D. Ward, Nagagireesh Bojanala, Kaveh Ashrafi, Teresita U. Bernal, Keith R. Yamamoto
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 9, Iss 12, p e1003992 (2013)
PLoS genetics, vol 9, iss 12
PLoS Genetics, Vol 9, Iss 12, p e1003992 (2013)
PLoS genetics, vol 9, iss 12
Individual metazoan transcription factors (TFs) regulate distinct sets of genes depending on cell type and developmental or physiological context. The precise mechanisms by which regulatory information from ligands, genomic sequence elements, co-fact
Publikováno v:
Genes to Cells. 5:711-723
Background: Nuclear receptors are essential players in the development of all metazoans. The nematode Caenorhabditis elegans possesses more than 200 putative nuclear receptor genes, several times more than the number known in any other organism. Very