Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Masaki Tokunaga"'
Autor:
Keisuke Takahata, Yasuyuki Kimura, Chie Seki, Masaki Tokunaga, Masanori Ichise, Kazunori Kawamura, Maiko Ono, Soichiro Kitamura, Manabu Kubota, Sho Moriguchi, Tatsuya Ishii, Yuhei Takado, Fumitoshi Niwa, Hironobu Endo, Tomohisa Nagashima, Yoko Ikoma, Ming-Rong Zhang, Tetsuya Suhara, Makoto Higuchi
Publikováno v:
EJNMMI Research, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Background α-Amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor is a primary mediator of fast glutamatergic excitatory signaling in the brain and has been implicated in diverse neuropsychiatric diseases. We recently developed a
Externí odkaz:
https://doaj.org/article/ccda0efb0af84ee5ab13c5318aab6d87
Autor:
Yosuke Nakatani, Michiyuki Suzuki, Masaki Tokunaga, Jun Maeda, Miyuki Sakai, Hiroki Ishihara, Takashi Yoshinaga, Osamu Takenaka, Ming-Rong Zhang, Tetsuya Suhara, Makoto Higuchi
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75040 (2013)
Serotonin 1A (5-HT1A) receptors have been mechanistically implicated in micturition control, and there has been a need for an appropriate biomarker surrogating the potency of a provisional drug acting on this receptor system for developing a new ther
Externí odkaz:
https://doaj.org/article/c158a5856b2347dba5decba4be3176a6
Autor:
Kenji Tagai, Jun Maeda, Hiroyuki Takuwa, Kazunori Kawamura, Masafumi Shimojo, Chie Seki, Sho Moriguchi, Hitoshi Shinotoh, Keisuke Takahata, Yasuyuki Kimura, Tetsuya Suhara, Soichiro Kitamura, Masanori Ichise, Hitoshi Shimada, Makoto Higuchi, Manabu Kubota, Ming-Rong Zhang, João M. N. Duarte, Takayuki Obata, Jin Nakahara, Masaki Tokunaga, Yuhei Takado, Yutaka Tomita
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 41:2928-2943
Fluctuations of neuronal activities in the brain may underlie relatively slow components of neurofunctional alterations, which can be modulated by food intake and related systemic metabolic statuses. Glutamatergic neurotransmission plays a major role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebe394ffeabe134760b39013895e6168
https://doi.org/10.1177/0271678x211004150
https://doi.org/10.1177/0271678x211004150
Autor:
Manabu, Kubota, Yasuyuki, Kimura, Masafumi, Shimojo, Yuhei, Takado, M.N. Duarte, Joao, Hiroyuki, Takuwa, Chie, Seki, Hitoshi, Shimada, Hitoshi, Shinoto, Keisuke, Takahata, Soichiro, Kitamura, Sho, Moriguchi, Kenji, Tagai, Takayuki, Obata, Nakahara, Jin, Yutaka, Tomita, Masaki, Tokunaga, Jun, Maeda, Kazunori, Kawamura, Zhang, Ming-Rong, Masanori, Ichise, Tetsuya, Suhara, Makoto, Higuchi
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 41(11):2928-2943
Fluctuations of neuronal activities in the brain may underlie relatively slow components of neurofunctional alterations, which can be modulated by food intake and related systemic metabolic statuses. Glutamatergic neurotransmission plays a major role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::9cff04b052f1a28260ffcce6fd154573
https://repo.qst.go.jp/records/82681
https://repo.qst.go.jp/records/82681
Autor:
Naruhiko Sahara, Takeharu Minamihisamatsu, Maiko Ono, Hiroyuki Takuwa, Masaki Tokunaga, Masayuki Fujinaga, Yuhei Takado, Chie Seki, Anton Maximov, Tetsuya Suhara, Tatsuya Kikuchi, Jun Maeda, Norihiro Suzuki, Makoto Higuchi, Koki Mimura, Yuji Nagai, Ming-Rong Zhang, Masafumi Shimojo, Yutaka Tomita, Takafumi Minamimoto, Manami Takahashi, Maki Okada
Publikováno v:
The EMBO Journal
Positron emission tomography (PET) allows biomolecular tracking but PET monitoring of brain networks has been hampered by a lack of suitable reporters. Here, we take advantage of bacterial dihydrofolate reductase, ecDHFR, and its unique antagonist, T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06aa89588044f0d93948b5cfdb83091b
https://doi.org/10.15252/embj.2021107757
https://doi.org/10.15252/embj.2021107757
Autor:
Taeko Kimura, Chie Seki, Shigeyuki Honda, Taizo Ishikawa, Takehiro Kudo, Masaki Tokunaga, Naruhiko Sahara, Jun Maeda, Masafumi Shimojo, Kazuaki Sampei, Makoto Higuchi, Hiroyuki Takuwa, Yuhei Takado, Maiko Ono
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c645254f53de4f0c0167e7dfe111a238
https://doi.org/10.1002/alz.038201
https://doi.org/10.1002/alz.038201
Autor:
Maki Okada, Ming-Rong Zhang, Makoto Higuchi, Masafumi Shimojo, Jun Maeda, Tetsuya Suhara, Manami Takahashi, Takeharu Minamihisamatsu, Norihiro Suzuki, Koki Mimura, Takafumi Minamimoto, Chie Seki, Hiroyuki Takuwa, Masayuki Fujinaga, Yuji Nagai, Yutaka Tomita, Naruhiko Sahara, Maiko Ono, Anton Maximov, Tatsuya Kikuchi, Masaki Tokunaga, Yuhei Takado
Positron Emission Tomography (PET) allows biomolecular tracking, while PET monitoring of brain networks has been hampered by the lack of a suitable reporter. Here, we describe in vivo brain imaging that takes advantage of bacterial dihydrofolate redu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7423a46b29e68c4e477b733eabbf6a3
Autor:
Jun Maeda, Satoshi Tsukamoto, Ichio Aoki, Chie Seki, Takeharu Minamihisamatsu, Keiichiro Minatohara, Makoto Higuchi, Maiko Ono, Tetsuya Suhara, Hiroyuki Takuwa, Masafumi Shimojo, Masaki Tokunaga, Yuhei Takado, Ming-Rong Zhang, Naruhiko Sahara, Takuya Urushihata, Kazunori Kawamura
Publikováno v:
J Neurosci
Synaptic dysfunction provoking dysregulated cortical neural circuits is currently hypothesized as a key pathophysiological process underlying clinical manifestations in Alzheimer's disease and related neurodegenerative tauopathies. Here, we conducted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a2a0dd71750a8ac7c58b4a6c454e53
https://pubmed.ncbi.nlm.nih.gov/32265258
https://pubmed.ncbi.nlm.nih.gov/32265258
Publikováno v:
Journal of Alzheimer's Disease. 64:S353-S359
Tauopathy is characterized by the fibrillar tau accumulation in neurons and glial cells. In order to advance our understanding of the causative mechanisms of tauopathy, neuroinflammation, which has been suggested to play important roles in disease pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59d4732edb6dc064eb9c852d22f7fc9
https://doi.org/10.3233/jad-179933
https://doi.org/10.3233/jad-179933
Autor:
Shimojo, Masafumi, Ono, Maiko, Takuwa, Hiroyuki, Mimura, Koki, Nagai, Yuji, Fujinaga, Masayuki, Kikuchi, Tatsuya, Okada, Maki, Seki, Chie, Tokunaga, Masaki, Maeda, Jun, Takado, Yuhei, Takahashi, Manami, Minamihisamatsu, Takeharu, Ming-Rong, Zhang, Tomita, Yutaka, Suzuki, Norihiro, Maximov, Anton, Suhara, Tetsuya, Minamimoto, Takafumi, Sahara, Naruhiko, Higuchi, Makoto, Masafumi, Shimojo, Maiko, Ono, Hiroyuki, Takuwa, Koki, Mimura, Yuji, Nagai, Masayuki, Fujinaga, Tatsuya, Kikuchi, Maki, Okada, Chie, Seki, Masaki, Tokunaga, Jun, Maeda, Yuhei, Takado, Takeharu, Minamihisamatsu, Zhang, Ming-Rong, Tetsuya, Suhara, Takafumi, Minamimoto, Naruhiko, Sahara, Makoto, Higuchi
Publikováno v:
The EMBO Journal. 40(22):e107757
Positron emission tomography (PET) allows biomolecular tracking but PET monitoring of brain networks has been hampered by a lack of suitable reporters. Here, we take advantage of bacterial dihydrofolate reductase, ecDHFR, and its unique antagonist, T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::59e8f2eeca35f0acaefce8e6eb6e9264
https://repo.qst.go.jp/records/84657
https://repo.qst.go.jp/records/84657