Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Masaki Shirayama"'
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112408- (2023)
Summary: Argonaute/small RNA pathways and heterochromatin work together to propagate transgenerational gene silencing, but the mechanisms behind their interaction are not well understood. Here, we show that induction of heterochromatin silencing in C
Externí odkaz:
https://doaj.org/article/9736d36d55134e42911df4acf028d412
Autor:
Meetu Seth, Masaki Shirayama, Wen Tang, En-Zhi Shen, Shikui Tu, Heng-Chi Lee, Zhiping Weng, Craig C. Mello
Publikováno v:
Cell Reports, Vol 22, Iss 9, Pp 2254-2264 (2018)
Summary: Protein-coding genes undergo a wide array of regulatory interactions with factors that engage non-coding regions. Open reading frames (ORFs), in contrast, are thought to be constrained by coding function, precluding a major role in gene regu
Externí odkaz:
https://doaj.org/article/734f1dd24ee44f19ba1286700306a1a0
Autor:
Shikui Tu, En-zhi Shen, Craig C. Mello, Masaki Shirayama, Wen Tang, Meetu Seth, Zhiping Weng, Heng-Chi Lee
Publikováno v:
Cell Reports, Vol 22, Iss 9, Pp 2254-2264 (2018)
Cell reports
Cell reports
SUMMARY Protein-coding genes undergo a wide array of regulatory interactions with factors that engage non-coding regions. Open reading frames (ORFs), in contrast, are thought to be constrained by coding function, precluding a major role in gene regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a384c742f039c8d4b681031a90504b
http://www.sciencedirect.com/science/article/pii/S2211124718301773
http://www.sciencedirect.com/science/article/pii/S2211124718301773
Publikováno v:
Dev Cell
Summary In animals, Argonaute small-RNA pathways scan germline transcripts to silence self-replicating genetic elements. However, little is known about how endogenous gene expression is recognized and licensed. Here, we show that the presence of intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1754b3a3c26abc001125504d1b47f4f
https://doi.org/10.1016/j.devcel.2021.08.022
https://doi.org/10.1016/j.devcel.2021.08.022
Autor:
Masaki Shirayama, Masato Kato, Tetsuhiko Miyadera, Takeshi Sugita, Takemasa Fujiseki, Shota Hara, Hideyuki Kadowaki, Daisuke Murata, Masayuki Chikamatsu, Hiroyuki Fujiwara
Publikováno v:
Journal of Applied Physics; 2016, Vol. 119 Issue 11, p1-12, 12p, 1 Black and White Photograph, 5 Diagrams, 5 Graphs
Autor:
Masaki Shirayama, Eddie G. Dominguez, Alex R. Villarreal, Ahna R. Skop, Megan M. Gnazzo, Eva-Maria E. Uhlemann
Publikováno v:
Molecular Biology of the Cell
The mechanisms that mediate the temporal and spatial recruitment of cell division factors to the spindle midzone and midbody remain unclear. Cell division is regulated by the conserved RNA-binding protein, ATX-2/Ataxin-2, which facilitates the target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18130c59e2c309da1d564d59d0aa7c5d
http://europepmc.org/articles/PMC5063614
http://europepmc.org/articles/PMC5063614
Autor:
Si-Yuan Dai, Zhiping Weng, Ahmet R. Ozturk, Shikui Tu, Wen Tang, En-zhi Shen, Craig C. Mello, Masaki Shirayama, Hao Chen, Yue-He Ding
SUMMARYpiRNAs (Piwi-interacting small RNAs) engage Piwi Argonautes to silence transposons and promote fertility in animal germlines. Genetic and computational studies have suggested thatC. eleganspiRNAs tolerate mismatched pairing and in principle co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f34658027f88066e73acdcd0eab795
https://europepmc.org/articles/PMC5905434/
https://europepmc.org/articles/PMC5905434/
Autor:
Meetu Seth, En-zhi Shen, Zhiping Weng, Craig C. Mello, Shikui Tu, Wen Tang, Heng-Chi Lee, Masaki Shirayama
Publikováno v:
SSRN Electronic Journal.
Piwi Argonautes and their piRNA co-factors silence transposons in animal germlines. However, little is known about whether and how piRNAs regulate other germline-expressed mRNAs. Here we explore Piwi-mediated gene regulation in C. elegans. We show th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22c6442b01ad57221edd324d9ab8dcd9
https://doi.org/10.2139/ssrn.3155858
https://doi.org/10.2139/ssrn.3155858
Autor:
Daniel J. Durning, Meetu Seth, Hao Chen, En-zhi Shen, Takao Ishidate, Rita Sharma, Craig C. Mello, Ahmet R. Ozturk, Masaki Shirayama
Publikováno v:
SSRN Electronic Journal.
The capacity to adopt durable new gene expression states, and hence stable heritable and distinct physical properties, underlies the remarkable diversity of somatic cell types in multicellular animals. It is less clear, however, to what extent change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df8035f8abc9582eaf34471a7ff99eb6
https://doi.org/10.2139/ssrn.3155668
https://doi.org/10.2139/ssrn.3155668
Publikováno v:
SSRN Electronic Journal.
In metazoans, Piwi-related Argonaute proteins engage piRNAs (Piwi-interacting small RNAs) to defend the genome against invasive nucleic acids, such as transposable elements. Yet many organisms — including worms and humans — express thousands of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::486b5b9002a4ae4c4f59d5dcb273f1ba
https://doi.org/10.2139/ssrn.3155539
https://doi.org/10.2139/ssrn.3155539