Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Masaki Kawamata"'
Autor:
Aya Yoshimura, Naoki Adachi, Hitomi Matsuno, Masaki Kawamata, Yusuke Yoshioka, Hisae Kikuchi, Haruki Odaka, Tadahiro Numakawa, Hiroshi Kunugi, Takahiro Ochiya, Yoshitaka Tamai
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 1 (2018)
Extracellular vesicles (EVs) can modulate microenvironments by transferring biomolecules, including RNAs and proteins derived from releasing cells, to target cells. To understand the molecular mechanisms maintaining the neural stem cell (NSC) niche t
Externí odkaz:
https://doaj.org/article/f1670e05a3eb49b4a74cc61eeb122780
Autor:
Shinobu Ueda, Masaki Kawamata, Takumi Teratani, Taku Shimizu, Yoshitaka Tamai, Hiromasa Ogawa, Katsuyuki Hayashi, Hiroyuki Tsuda, Takahiro Ochiya
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2800 (2008)
The rat is a reference animal model for physiological studies and for the analysis of multigenic human diseases such as hypertension, diabetes, neurological disorders, and cancer. The rats have long been used in extensive chemical carcinogenesis stud
Externí odkaz:
https://doaj.org/article/da6b519016e644e8b64a22ed17fe2e1c
Publikováno v:
Nature Biomedical Engineering. 7:672-691
The precise regulation of the activity of Cas9 is crucial for safe and efficient editing. Here we show that the genome-editing activity of Cas9 can be constrained by the addition of cytosine stretches to the 5′-end of conventional single-guide RNAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dc9058dddcb86fc194b19baffcc06d1
https://doi.org/10.1038/s41551-023-01011-7
https://doi.org/10.1038/s41551-023-01011-7
Publikováno v:
FEBS Letters. 594:114-125
The immediate deterioration of primary human hepatocytes (PHHs) during culture limits their utility in drug discovery studies. Here, we report that a cocktail of four small molecule signaling inhibitors, termed YPAC, is useful for maintaining various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56234849a27224227e1dabcbdd2e615
https://doi.org/10.1002/1873-3468.13582
https://doi.org/10.1002/1873-3468.13582
CRSIPR-Cas9 system has opened up the avenue to efficient genome editing1–4. However, together with known off-target effects, several concerns of current CRISPR-Cas9 platform, including severe DNA damage, cytotoxicity, and large genomic alteration,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50315cccfd9d8edb8f505cfe4a7c245b
https://doi.org/10.1101/2020.10.31.361733
https://doi.org/10.1101/2020.10.31.361733
Autor:
Masaki Kawamata1, Atsushi Suzuki1,2 suzukicks@bioreg.kyushu-u.ac.jp
Publikováno v:
Journal of Biochemistry. Jul2017, Vol. 162 Issue 1, p11-16. 6p.
Autor:
Atsushi Suzuki, Masaki Kawamata
Publikováno v:
The Journal of Biochemistry. 162:11-16
The lineage of a somatic cell can be altered by targeting its signaling networks with small molecules and/or genetically altering the expression of key transcription factors. Depending on the combination of factors, fibroblasts can be fully reprogram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3beb42167c53f3d3ca3b9e06a1a94a
https://doi.org/10.1093/jb/mvx028
https://doi.org/10.1093/jb/mvx028
Autor:
Keitaro Hagiwara, Ryou U. Takahashi, Takeshi Katsuda, Yusuke Yamamoto, Fernando D. Camargo, Takahiro Ochiya, Masaki Kawamata
Publikováno v:
Cell Stem Cell. 20:41-55
A challenge for advancing approaches to liver regeneration is loss of functional differentiation capacity when hepatocyte progenitors are maintained in culture. Recent lineage-tracing studies have shown that mature hepatocytes (MHs) convert to an imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75a0e3a1ff1da0e0bf16d8186bb16f8a
https://doi.org/10.1016/j.stem.2016.10.007
https://doi.org/10.1016/j.stem.2016.10.007
Autor:
Maiko Terada, Masaki Kawamata, Ryota Kimura, Sayaka Sekiya, Go Nagamatsu, Katsuhiko Hayashi, Kenichi Horisawa, Atsushi Suzuki
Publikováno v:
genesis. 57
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e289fd03c0b067202a6cf01a8cac45aa
https://doi.org/10.1002/dvg.23349
https://doi.org/10.1002/dvg.23349
Autor:
Kenichi Horisawa, Atsushi Suzuki, Katsuhiko Hayashi, Masaki Kawamata, Ryota Kimura, Maiko Terada, Sayaka Sekiya, Go Nagamatsu
Publikováno v:
Genesis (New York, N.Y. : 2000)REFERENCES. 57(11-12)
Nanog is a core transcription factor specifically expressed not only in the pluripotent stem cells (PSCs), such as embryonic stem cells (ESCs), embryonic germ cells (EGCs), and induced PSCs (iPSCs), but also in the unipotent primordial germ cells (PG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc58b96bae2b979aef2aa3b841a9655b
https://pubmed.ncbi.nlm.nih.gov/31513343
https://pubmed.ncbi.nlm.nih.gov/31513343