Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Masaki KAMEYAMA"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Parkinson’s disease (PD), a common neurodegenerative disease characterized by motor dysfunction, results from the death of dopaminergic neurons in the substantia nigra pars compacta (SNc). Although the precise causes of PD are still unknown, severa
Externí odkaz:
https://doaj.org/article/4c09731535dd494ca64d97df983e2fca
Publikováno v:
Journal of Pharmacological Sciences, Vol 137, Iss 2, Pp 187-194 (2018)
Activity of cardiac Cav1.2 channels is enhanced by cyclic AMP-PKA signaling. In this study, we studied the effects of PKA phosphorylation on the binding of calmodulin to the fragment peptide of the proximal C-terminal tail of α1C subunit (CT1, a.a.
Externí odkaz:
https://doaj.org/article/de87824c033c48a2997242118944e138
Publikováno v:
Journal of Pharmacological Sciences, Vol 133, Iss 4, Pp 240-246 (2017)
Cardiac Cav1.2 channels, coupling membrane stimulation to intracellular Ca2+ signaling, are regulated by multiple cytoplasmic factors, such as calmodulin (CaM), phosphorylation, Ca2+, ATP and intramolecular fragments of the channel. The interaction b
Externí odkaz:
https://doaj.org/article/37ed073995fc4052a1d55fefaf29f8c9
Autor:
Yoshio YOSHIKUWA, Haruyuki KOMETANI, Yoshinori MIYAMOTO, Masaki KAMEYAMA, Manabu DEGUCHI, Toshihiko MIZUTANI
Publikováno v:
Nihon Kikai Gakkai ronbunshu, Vol 84, Iss 861, Pp 17-00450-17-00450 (2018)
Motors are used in many appliances, and noise reduction is strongly demanded. One of the main causes of noise is electromagnetic excitation force and it is well known that the excitation force is increased by the eccentricity of the rotor to the stat
Externí odkaz:
https://doaj.org/article/f35be1dc54a544ddb8016fa129934c3c
Autor:
Meimi Zhao, Rui Feng, Dongxue Shao, Shuyuan Liu, Ming Lei, Hongmei Wang, Xuefei Sun, Feng Guo, Huiyuan Hu, Masaki Kameyama, Liying Hao
Publikováno v:
Journal of Pharmacological Sciences, Vol 129, Iss 3, Pp 143-149 (2015)
This study aimed to investigate the intracellular Mg2+ regulation of the L-type Ca2+ channels in guinea pig ventricular myocytes. By adopting the inside-out configuration of the patch clamp technique, single channel currents of the L-type Ca2+ channe
Externí odkaz:
https://doaj.org/article/cdbe2d1cba1a42c18af7429e014154e5
Regulation of the Cav1.2 cardiac channel by redox via modulation of CaM interaction with the channel
Publikováno v:
Journal of Pharmacological Sciences, Vol 128, Iss 3, Pp 137-143 (2015)
Although it has been well documented that redox can modulate Cav1.2 channel activity, the underlying mechanisms are not fully understood. In our study, we examined the effects of redox on Cav1.2 channel activity and on CaM interaction with the Cav1.2
Externí odkaz:
https://doaj.org/article/59f027f48aee4e559695587c156e092a
Autor:
Wanying Jia, Xiaoxue Xu, Qinghua Gao, Yuting Wang, Rui Feng, Masaki Kameyama, Yujun Wan, Wuyang Wang, Etsuko Minobe, Xiaohong Zhang, Junyan Liu, Zhiyi Yu, Jianjun Xu, Feng Guo
Publikováno v:
Neurochemical Research. 46:523-534
Voltage-gated sodium channels (VGSCs) are fundamental to the initiation and propagation of action potentials in excitable cells. Ca2+/calmodulin (CaM) binds to VGSC type II (NaV1.2) isoleucine and glutamine (IQ) motif. An autism-associated mutation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0f42bf6231a55e4c69bf12e05f75dca
https://doi.org/10.1007/s11064-020-03189-7
https://doi.org/10.1007/s11064-020-03189-7
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 472:911-922
TWIK-related acid-sensitive K+ (TASK) channels contribute to the resting membrane potential in various kinds of cells, such as brain neurons, smooth muscle cells, and endocrine cells. Loss-of-function mutations at multiple sites in the KCNK3 gene enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565e0b04114a847d9903a4fe91e9a73c
https://doi.org/10.1007/s00424-020-02403-3
https://doi.org/10.1007/s00424-020-02403-3
Autor:
Yuan Yuan, Xuefei Sun, Lifeng Yu, Rui Feng, Liying Hao, Zhengnan Zhu, Sun Xuanxuan, Masaki Kameyama, Jingyang Su, Qinghua Gao, Dongxue Shao
Publikováno v:
American Journal of Physiology-Cell Physiology. 318:C991-C1004
Calmodulin (CaM) mutations are associated with congenital long QT (LQT) syndrome (LQTS), which may be related to the dysregulation of the cardiac-predominant Ca2+channel isoform CaV1.2. Among various mutants, CaM-E141G was identified as a critical mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1644555a7d8e6804114908b33ead8cc3
https://doi.org/10.1152/ajpcell.00019.2020
https://doi.org/10.1152/ajpcell.00019.2020
Publikováno v:
Frontiers in cellular neuroscience. 16
Parkinson's disease (PD), a common neurodegenerative disease characterized by motor dysfunction, results from the death of dopaminergic neurons in the substantia nigra pars compacta (SNc). Although the precise causes of PD are still unknown, several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f99f1afab01594454a47ef5e2d58b3fe
https://pubmed.ncbi.nlm.nih.gov/35496903
https://pubmed.ncbi.nlm.nih.gov/35496903