Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Masaki Inada"'
Autor:
Tsukasa Tominari, Chiho Matsumoto, Yuki Tanaka, Kensuke Shimizu, Masaru Takatoya, Moe Sugasaki, Kento Karouji, Urara Kasuga, Chisato Miyaura, Shinji Miyata, Yoshifumi Itoh, Michiko Hirata, Masaki Inada
Publikováno v:
Biology, Vol 13, Iss 9, p 692 (2024)
Toll-like receptors (TLRs) are pattern recognition receptors expressed in immune cells, including neutrophils, macrophages, and dendritic cells. Microbe-associated molecular patterns, including bacterial components, membranes, nucleic acids, and flag
Externí odkaz:
https://doaj.org/article/ec77b65d4ae34276af606d845596f06e
Autor:
Ryo Tanaka, Shosei Yoshinouchi, Kento Karouji, Yuki Tanaka, Tsukasa Tominari, Michiko Hirata, Chiho Matsumoto, Yoshifumi Itoh, Chisato Miyaura, Masaki Inada
Publikováno v:
FEBS Open Bio, Vol 13, Iss 1, Pp 51-59 (2023)
The pathologies and lethality of lung cancers are associated with smoking, lifestyle, and genomic factors. Several experimental mouse models of lung cancer, including those induced via intrapulmonary injection and intratracheal injection, have been r
Externí odkaz:
https://doaj.org/article/4b1edfdce95048dca8a58f380a2d1363
Autor:
Tsukasa Tominari, Ayumi Sanada, Ryota Ichimaru, Chiho Matsumoto, Michiko Hirata, Yoshifumi Itoh, Yukihiro Numabe, Chisato Miyaura, Masaki Inada
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Periodontitis is an inflammatory disease associated with severe alveolar bone loss and is dominantly induced by lipopolysaccharide from Gram-negative bacteria; however, the role of Gram-positive bacteria in periodontal bone resorption remain
Externí odkaz:
https://doaj.org/article/805e60ede4434cd0b11c984d4a9456d6
Autor:
Ko Igarashi, Yoshihiro Yui, Kenta Watanabe, Jun Kumai, Yasuko Nishizawa, Chisato Miyaura, Masaki Inada, Satoru Sasagawa
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Clinical trials have been conducted to clarify the beneficial effects of VD3 (1α,25-dihydroxy vitamin D3, also known as calcitriol) treatment in prostate cancer. However, the molecular mechanisms underlying these effects are not
Externí odkaz:
https://doaj.org/article/53c782edb44b4a08ad00bfdf0b6b1cff
Autor:
Toshinobu Omiya, Jun Hirose, Yasunori Omata, Tsukasa Tominari, Masaki Inada, Hisato Watanabe, Takeshi Miyamoto, Sakae Tanaka
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100289- (2020)
Bisphosphonates and the anti-receptor activator of nuclear factor-kappa B ligand (RANKL) antibody denosumab are effective anti-resorptive drugs commonly prescribed for osteoporosis. Both drugs may, however, have intolerable side effects; so, it is cr
Externí odkaz:
https://doaj.org/article/bc31f1c0e43045abbe6dc9a7a1a5b3d2
Autor:
Tsukasa Tominari, Chiho Matsumoto, Kenta Watanabe, Michiko Hirata, Florian M.W. Grundler, Chisato Miyaura, Masaki Inada
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 522-527 (2015)
Epigallocatechin gallate (EGCG), a major polyphenol in green tea, possesses antioxidant properties and regulates various cell functions. Here, we examined the function of EGCG in inflammatory bone resorption. In calvarial organ cultures, lipopolysacc
Externí odkaz:
https://doaj.org/article/90814e334c46429382704b72a1dec947
Autor:
Hidenori Fujita, Akira Gomori, Yayoi Fujioka, Yuki Kataoka, Kenji Tanaka, Akihiro Hashimoto, Takamasa Suzuki, Kenjiro Ito, Tomonori Haruma, Hiromi Yamamoto-Yokoi, Naomoto Harada, Motomu Sakuragi, Nobuyuki Oda, Kenichi Matsuo, Masaki Inada, Kazuhiko Yonekura
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164830 (2016)
Approximately 25-40% of patients with lung cancer show bone metastasis. Bone modifying agents reduce skeletal-related events (SREs), but they do not significantly improve overall survival. Therefore, novel therapeutic approaches are urgently required
Externí odkaz:
https://doaj.org/article/18aa7f8031364109aa46297c65429dee
Publikováno v:
Journal of Pharmacological Sciences, Vol 119, Iss 4, Pp 390-394 (2012)
Nobiletin, a polymethoxy flavonoid (PMF), inhibits systemic bone resorption and maintains bone mass in estrogen-deficient ovariectomized mice. This study examined the antiinflammatory effects of PMFs, nobiletin, and tangeretin on lipopolysaccharide (
Externí odkaz:
https://doaj.org/article/1db27f13262049ad82ef8c7f8909fe1f
Autor:
Suguru Harada, Tsukasa Tominari, Chiho Matsumoto, Michiko Hirata, Morichika Takita, Masaki Inada, Chisato Miyaura
Publikováno v:
Journal of Pharmacological Sciences, Vol 115, Iss 1, Pp 89-93 (2011)
Nobiletin, a polymethoxy flavonoid, prevents cancer and inflammation, but the roles of nobiletin in bone are unclear. We examined the effects of nobiletin on bone resorption in vitro and on bone mass in ovariectomized (OVX) mice in vivo. In vitro, no
Externí odkaz:
https://doaj.org/article/6d92688c1215413ab5962f0fde5ead71
Autor:
Shigeru Matsumoto, Tsukasa Tominari, Chiho Matsumoto, Shosei Yoshinouchi, Ryota Ichimaru, Kenta Watanabe, Michiko Hirata, Florian M. W. Grundler, Chisato Miyaura, Masaki Inada
Publikováno v:
Pharmaceuticals, Vol 11, Iss 1, p 7 (2018)
Polymethoxyflavonoids (PMFs) are a family of the natural compounds that mainly compise nobiletin, tangeretin, heptamethoxyflavone (HMF), and tetramethoxyflavone (TMF) in citrus fruits. PMFs have shown various biological functions, including anti-oxid
Externí odkaz:
https://doaj.org/article/8f1f68e6b1da4c2e974459999eaea990