Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Masaki Fukata"'
Autor:
Chihiro Nakamoto, Yuhei Goto, Yoko Tomizawa, Yuko Fukata, Masaki Fukata, Kasper Harpsøe, David E. Gloriam, Kazuhiro Aoki, Tomonori Takeuchi
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-14 (2021)
Abstract Dopamine (DA) and norepinephrine (NE) are pivotal neuromodulators that regulate a broad range of brain functions, often in concert. Despite their physiological importance, untangling the relationship between DA and NE in the fine control of
Externí odkaz:
https://doaj.org/article/f81a0da714344452943514f5d04d1252
Autor:
Tomoyuki Yoshida, Atsushi Yamagata, Ayako Imai, Juhyon Kim, Hironori Izumi, Shogo Nakashima, Tomoko Shiroshima, Asami Maeda, Shiho Iwasawa-Okamoto, Kenji Azechi, Fumina Osaka, Takashi Saitoh, Katsumi Maenaka, Takashi Shimada, Yuko Fukata, Masaki Fukata, Jumpei Matsumoto, Hisao Nishijo, Keizo Takao, Shinji Tanaka, Shigeo Okabe, Katsuhiko Tabuchi, Takeshi Uemura, Masayoshi Mishina, Hisashi Mori, Shuya Fukai
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Mutations of Neuroligin 3 (NLGN3) have been associated with autism spectrum disorder (ASD). Here, the authors identify a previously undescribed interaction between NLGN3 and a splice variant of protein tyrosine phosphatase δ (PTP δ) and its role in
Externí odkaz:
https://doaj.org/article/088ec8c07114426fb988df9303a95e47
Autor:
Hidenori Watanabe, Hiromi Sano, Satomi Chiken, Kenta Kobayashi, Yuko Fukata, Masaki Fukata, Hajime Mushiake, Atsushi Nambu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Non-human primates are useful models for understanding the human brain but application of optogenetics to non-human primates is challenging. The authors used optogenetic intracortical microstimulation in the primary motor cortex of macaques to elicit
Externí odkaz:
https://doaj.org/article/fab4913add8442dda3fa032854555f01
Autor:
Norihiko Yokoi, Yuko Fukata, Kei Okatsu, Atsushi Yamagata, Yan Liu, Makoto Sanbo, Yuri Miyazaki, Teppei Goto, Manabu Abe, Hidetoshi Kassai, Kenji Sakimura, Dies Meijer, Masumi Hirabayashi, Shuya Fukai, Masaki Fukata
Publikováno v:
Cell Reports, Vol 37, Iss 11, Pp 110107- (2021)
Summary: What percentage of the protein function is required to prevent disease symptoms is a fundamental question in genetic disorders. Decreased transsynaptic LGI1-ADAM22 protein complexes, because of their mutations or autoantibodies, cause epilep
Externí odkaz:
https://doaj.org/article/5da5384129fc4484b4ce507f1ce2786f
Autor:
Daisuke Hasegawa, Yumi Ohnishi, Eiji Koyama, Satoru Matsunaga, Shouhei Ohtani, Akio Nakanishi, Takanori Shiga, James K. Chambers, Kazuyuki Uchida, Norihiko Yokoi, Yuko Fukata, Masaki Fukata
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 33, Iss 3, Pp 1440-1445 (2019)
Abstract A 7‐year‐old neutered female domestic shorthaired cat born in Poland and then moved to Japan presented to the local clinic with recent onset of convulsive cluster seizures and status epilepticus. Magnetic resonance imaging revealed bilat
Externí odkaz:
https://doaj.org/article/bf358008894b434286114b80b568627e
Autor:
Atsushi Yamagata, Yuri Miyazaki, Norihiko Yokoi, Hideki Shigematsu, Yusuke Sato, Sakurako Goto-Ito, Asami Maeda, Teppei Goto, Makoto Sanbo, Masumi Hirabayashi, Mikako Shirouzu, Yuko Fukata, Masaki Fukata, Shuya Fukai
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
LGI1 is an epilepsy-related gene that encodes a secreted neuronal protein. Here the authors present the crystal structure of LGI1 bound to its receptor ADAM22, which provides structural insights into epilepsy-causing LGI1 mutations and might facilita
Externí odkaz:
https://doaj.org/article/c8d56a79c67b43399c581db013e3959e
Autor:
Sylvie Gory-Fauré, Vanessa Windscheid, Jacques Brocard, Sylvie Montessuit, Ryouhei Tsutsumi, Eric Denarier, Yuko Fukata, Christophe Bosc, Julie Delaroche, Nora Collomb, Masaki Fukata, Jean-Claude Martinou, Karin Pernet-Gallay, Annie Andrieux
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114905 (2014)
MAP6 proteins (MAP6s), which include MAP6-N (also called Stable Tubule Only Polypeptide, or STOP) and MAP6d1 (MAP6 domain-containing protein 1, also called STOP-Like protein 21 kD, or SL21), bind to and stabilize microtubules. MAP6 deletion in mice s
Externí odkaz:
https://doaj.org/article/4417f4ab56dd4c18b3628bd3b8550d1f
Autor:
Eija H Seppälä, Tarja S Jokinen, Masaki Fukata, Yuko Fukata, Matthew T Webster, Elinor K Karlsson, Sami K Kilpinen, Frank Steffen, Elisabeth Dietschi, Tosso Leeb, Ranja Eklund, Xiaochu Zhao, Jennifer J Rilstone, Kerstin Lindblad-Toh, Berge A Minassian, Hannes Lohi
Publikováno v:
PLoS Genetics, Vol 7, Iss 7, p e1002194 (2011)
One quadrillion synapses are laid in the first two years of postnatal construction of the human brain, which are then pruned until age 10 to 500 trillion synapses composing the final network. Genetic epilepsies are the most common neurological diseas
Externí odkaz:
https://doaj.org/article/824d6668b4be4103ae7df8238c81b8f8
Autor:
Pleasantine Mill, Angela W S Lee, Yuko Fukata, Ryouhei Tsutsumi, Masaki Fukata, Margaret Keighren, Rebecca M Porter, Lisa McKie, Ian Smyth, Ian J Jackson
Publikováno v:
PLoS Genetics, Vol 5, Iss 11, p e1000748 (2009)
Palmitoylation is a key post-translational modification mediated by a family of DHHC-containing palmitoyl acyl-transferases (PATs). Unlike other lipid modifications, palmitoylation is reversible and thus often regulates dynamic protein interactions.
Externí odkaz:
https://doaj.org/article/09ed730c4c174956bbd080d242b8255b
Publikováno v:
Journal of Neuroscience; 6/5/2024, Vol. 44 Issue 23, p1-18, 18p