A self-marker-like protein governs hemocyte allorecognition in Halocynthia roretzi

Autor: Masaki Ema, Taizo Okada, Miki Takahashi, Masato Uchiyama, Hideo Kubo, Hideaki Moriyama, Hitoshi Miyakawa, Midori Matsumoto

Publikováno v: Zoological Letters, Vol 5, Iss 1, Pp 1-12 (2019)

Abstract Background Self-incompatibility, fusion/non-fusion reactions, and contact reactions (CRs) have all been identified as allorecognition phenomena in ascidians. CR is a reaction characteristic of the hemocytes of Halocynthia roretzi, whereby th

Externí odkaz: https://doaj.org/article/0d7bd95e63f7430888eb7da142f1e4d9

Covalent inhibitors of LgtC: a blueprint for the discovery of non-substrate-like inhibitors for bacterial glycosyltransferases

Autor: Mirella Vivoli, Nicholas J. Harmer, Gerd K. Wagner, Ruth Smith, Sebastian S. Gehrke, Niina Goos, Masaki Ema, Yong Xu

Publikováno v: Xu, Y, Smith, R, Vivoli, M, Ema, M, Goos, N, Gehrke, S, Harmer, N J & Wagner, G 2017, ' Covalent inhibitors of LgtC: a blueprint for the discovery of non-substrate-like inhibitors for bacterial glycosyltransferases ', Bioorganic and Medicinal Chemistry, vol. 25, no. 12, pp. 3182–3194 . https://doi.org/10.1016/j.bmc.2017.04.006

Non-substrate-like inhibitors of glycosyltransferases are sought after as chemical tools and potential lead compounds for medicinal chemistry, chemical biology and drug discovery. Here, we describe the discovery of a novel small molecular inhibitor c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72e5116a75bdf5eb589d3af611dc064
https://kclpure.kcl.ac.uk/en/publications/508908c9-ad6d-4939-a5dd-de845d48797a