Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Masaki Aota"'
Publikováno v:
2021 IEEE 20th International Conference on Trust, Security and Privacy in Computing and Communications (TrustCom).
Publikováno v:
ISCC
Vulnerability reports play an important role in cybersecurity. Mitigation of software vulnerabilities that can be exploited by attackers depends on disclosure of vulnerabilities. Information on vulnerability types or identifiers facilitates automatio
Autor:
Wataru Hamaguchi, Masaki Tomishima, Masaki Aota, Yasushi Amano, Hiroyuki Moriguchi, Masataka Morita, Naoyuki Masuda, Shugo Honda, Ayaka Chino, Koichi Yonezawa, Mayako Yamazaki
Publikováno v:
Bioorganicmedicinal chemistry. 27(16)
Phosphodiesterase 10A (PDE10A) inhibitors were designed and synthesized based on the dihydro-imidazobenzimidazole scaffold. Compound 5a showed moderate inhibitory activity and good permeability, but unfavorable high P-glycoprotein (P-gp) liability fo
Autor:
Koh Ono, Junichiro Nishizawa, Takaaki Koshiji, Kazuo Yamanaka, Masahiro Natsuaki, Yuko Morikami, Yoshihisa Nakagawa, Ryuzo Sakata, Michio Kawasuji, Takeshi Morimoto, Hiroyuki Yamamoto, Hiroyuki Nakajima, Yutaka Furukawa, Masaki Aota, Takeshi Kimura, Yukikatsu Okada, Masahiko Onoe
Publikováno v:
Atherosclerosis. 228:426-431
[Objective]Patients with coronary artery disease (CAD) often have prior stroke or concomitant extra-cardiac vascular disease (EVD) such as cerebral, aortic, or peripheral vascular disease. However, clinical outcomes after coronary revascularization i
Autor:
Noritaka Hamada, Shuichi Sakamoto, Itsuro Shimada, Tetsuya Kimizuka, Takashi Sugane, Kyouko Saita, Atsuyuki Kohara, Masaki Aota, Shin-ichi Tsukamoto, Takahiko Tobe, Wataru Hamaguchi, Morita Takuma, Hitoshi Doihara, Kyoichi Maeno, Yoshiaki Shimada, Takeshi Suzuki, Masako Furutani, Junji Miyata
Publikováno v:
Journal of Medicinal Chemistry. 54:387-391
We describe the preparation and evaluation of a novel series of glycine transporter 1 (GlyT1) inhibitors derived from a high-throughput screening hit. The SAR studies resulted in the discovery of 3-biphenyl-4-yl-4-(2-fluorophenyl)-5-isopropyl-4H-1,2,
Publikováno v:
Japanese Journal of Cardiovascular Surgery. 39:216-219
Publikováno v:
Japanese Journal of Cardiovascular Surgery. 38:380-384
乳頭筋断裂は稀ではあるが重篤な急性心筋梗塞後の合併症である.今回われわれは急性心筋梗塞後の後乳頭筋部分断裂に対し僧帽弁形成術,冠動脈バイパス術を施行し良好な成績を得た
Autor:
Hiroki Watanabe, Hiroki Shiomi, Kenji Nakatsuma, Takeshi Morimoto, Tomohiko Taniguchi, Yutaka Furukawa, Yoshihisa Nakagawa, Minoru Horie, Takeshi Kimura, Ryuzo Sakata, Akira Marui, Mitsuo Matsuda, Hirokazu Mitsuoka, Masahiko Onoe, Kazuo Yamanaka, Hisayoshi Fujiwara, Yoshiki Takatsu, Nobuhisa Ohno, Ryuji Nohara, Tomoyuki Murakami, Teruki Takeda, Masakiyo Nobuyoshi, Masashi Iwabuchi, Michiya Hanyu, Ryozo Tatami, Tsutomu Matsushita, Manabu Shirotani, Noboru Nishiwaki, Toru Kita, Yukikatsu Okada, Hiroshi Kato, Hiroshi Eizawa, Katsuhisa Is, Masaru Tanaka, Shogo Nakayama, Jong‐Dae Lee, Akira Nakano, Takaaki Koshiji, Koichi Morioka, Akinori Takizawa, Mitsuomi Shimamoto, Fumio Yamazaki, Masaaki Takahashi, Junichiro Nishizawa, Hiroyuki Takashima, Takashi Tamura, Masaki Aota, Mamoru Takahashi, Takafumi Tabata, Chuwa Tei, Shuichi Hamasaki, Yutaka Imoto, Hiroyuki Yamamoto, Hirofumi Kambara, Osamu Doi, Katsuhiko Matsuda, Masafumi Nara, Kazuaki Mitsudo, Kazushige Kadota, Tatsuhiko Komiya, Shinji Miki, Tetsu Mizoguchi, Hiroyuki Nakajima, Hisao Ogawa, Seigo Sugiyama, Michio Kawasuji, Syuji Moriyama, Ryuichi Hattori, Takeshi Aoyama, Makoto Araki, Satoru Suwa, Keiichi Tanbara, Kumiko Kitagawa, Misato Yamauchi, Naoko Okamoto, Yumika Fujino, Saori Tezuka, Asuka Saeki, Miya Hanazawa, Yuki Sato, Chikako Hibi, Hitomi Sasae, Emi Takinami, Yuriko Uchida, Yuko Yamamoto, Satoko Nishida, Mai Yoshimoto, Sachiko Maeda, Izumi Miki, Saeko Minematsu, Mitsuru Abe, Tomohisa Tada, Junichi Tazaki, Yoshihiro Kato, Mamoru Hayano, Akihiro Tokushige, Masahiro Natsuaki, Tetsu Nakajima
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Adjunctive thrombus aspiration ( TA ) during primary percutaneous coronary intervention ( PCI ) was reported to promote better coronary and myocardial reperfusion. However, long‐term mortality benefit of TA remains controversial. The obj
Publikováno v:
The Japanese Journal of Thoracic and Cardiovascular Surgery. 52:257-260
We report a case of a 42-year-old male with chronic thromboembolic pulmonary hypertension. His preoperative examination revealed severe hypoxemia (PaO2 48 mmHg, PaCO2 34 mmHg in room air), a mass in the right ventricle and severe pulmonary hypertensi
Publikováno v:
The Japanese Journal of Thoracic and Cardiovascular Surgery. 52:194-197
Aneurysm of the innominate artery is uncommon compared with other peripheral aneurysms, and holds the potential for rupture, embolization, or thrombosis as well as various complications caused by compression to the adjacent structures. The most effec