Zobrazeno 1 - 10
of 366
pro vyhledávání: '"Masakazu TANAKA"'
Publikováno v:
Molbank, Vol 2024, Iss 3, p M1848 (2024)
Naturally occurring carbohydrates serve as useful building blocks, and various derivatives have been employed in natural product syntheses. For instance, some aldoses can be converted to 1,3-dienes via the Wittig reaction at the anomeric carbon, acco
Externí odkaz:
https://doaj.org/article/1487ff57ad00461b97f6cabc261cfc08
Autor:
Akihiro Iyoshi, Atsushi Ueda, Tomohiro Umeno, Takuma Kato, Kazuhiro Hirayama, Mitsunobu Doi, Masakazu Tanaka
Publikováno v:
Molecules, Vol 29, Iss 18, p 4340 (2024)
Conformational freedom-restricted peptides, such as stapled peptides, play a crucial role in the advancement of functional peptide development. We synthesized stapled octapeptides using α-carbocyclic α,α-disubstituted α-amino acids, particularly
Externí odkaz:
https://doaj.org/article/fcd2f8df06b04149ab8e38e546cc95ec
Autor:
Masakazu Tanaka, Norihiro Takenouchi, Shiho Arishima, Toshio Matsuzaki, Satoshi Nozuma, Eiji Matsuura, Hiroshi Takashima, Ryuji Kubota
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 6858 (2024)
Increased human T-cell leukemia virus type 1 (HTLV-1) proviral load (PVL) is a significant risk factor for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). There is controversy surrounding whether HTLV-1-specific cytotoxic T lymph
Externí odkaz:
https://doaj.org/article/b6176717dee54f1b8ae26c82bcfff8e1
Autor:
Satoshi Nozuma, Akiko Yoshimura, Shun-Chung Pai, Hung-Jen Chen, Eiji Matsuura, Masakazu Tanaka, Daisuke Kodama, Mika Dozono, Toshio Matsuzaki, Hiroshi Takashima, Ya-Chien Yang, Ryuji Kubota
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 2, p e0011928 (2024)
BackgroundAlthough Japan is a major endemic area for human T-lymphotropic virus type 1 (HTLV-1) and the virus has been well-studied in this region, there is limited research on HTLV-1 in surrounding regions. In this study, we determined the complete
Externí odkaz:
https://doaj.org/article/2ce83ec0c5634d589081b6943a0c0900
Autor:
Eiji Matsuura, Satoshi Nozuma, Ayano Shigehisa, Mika Dozono, Tomonori Nakamura, Masakazu Tanaka, Ryuji Kubota, Akihiro Hashiguchi, Hiroshi Takashima
Publikováno v:
BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-6 (2023)
Abstract Background Sporadic late onset nemaline myopathy (SLONM) is a muscle disorder characterized by the presence of nemaline rods in muscle fibers. SLONM has no known genetic cause but has been associated with monoclonal gammopathy of undetermine
Externí odkaz:
https://doaj.org/article/2ee8ec70d7044e4a8e032fcf931c3e95
Autor:
Satoshi Nozuma, Eiji Matsuura, Yuichi Tashiro, Ryusei Nagata, Masahiro Ando, Yu Hiramatsu, Yujiro Higuchi, Yusuke Sakiyama, Akihiro Hashiguchi, Kumiko Michizono, Keiko Higashi, Toshio Matsuzaki, Daisuke Kodama, Masakazu Tanaka, Yoshihisa Yamano, Takashi Moritoyo, Ryuji Kubota, Hiroshi Takashima
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 2, Pp 237-245 (2023)
Abstract Objective HTLV‐1 infection causes HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP), resulting in loss of motor function. In this Phase 2 trial, we assessed the efficacy and safety of l‐arginine in patients with HAM
Externí odkaz:
https://doaj.org/article/2f465b03ac204e548d2aa22e4626964f
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 383 (2023)
The centrosome is involved in cytoplasmic microtubule organization during interphase and in mitotic spindle assembly during cell division. Centrosome amplification (abnormal proliferation of centrosome number) has been observed in several types of ca
Externí odkaz:
https://doaj.org/article/c07fbf9038dc478fb15b33091225a786
Autor:
Satoshi Nozuma, Eiji Matsuura, Masakazu Tanaka, Daisuke Kodama, Toshio Matsuzaki, Akiko Yoshimura, Yusuke Sakiyama, Shingo Nakahata, Kazuhiro Morishita, Yoshimi Enose-Akahata, Steven Jacoboson, Ryuji Kubota, Hiroshi Takashima
Publikováno v:
JCI Insight, Vol 8, Iss 7 (2023)
Human T lymphotropic virus type 1–assoicated (HTLV-1–associated) myelopathy/tropical spastic paraparesis (HAM/TSP) is a neuroinflammatory disease caused by the persistent proliferation of HTLV-1–infected T cells. Here, we performed a T cell rec
Externí odkaz:
https://doaj.org/article/dd32f1404890456588f10294cc14d342
Autor:
Ryusei Nagata, Eiji Matsuura, Satoshi Nozuma, Mika Dozono, Yutaka Noguchi, Masahiro Ando, Yu Hiramatsu, Daisuke Kodama, Masakazu Tanaka, Ryuji Kubota, Munekazu Yamakuchi, Yujiro Higuchi, Yusuke Sakiyama, Hitoshi Arata, Keiko Higashi, Teruto Hashiguchi, Shunya Nakane, Hiroshi Takashima
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
ObjectiveAutoimmune autonomic ganglionopathy (AAG) is a rare disorder characterized by autonomic failure associated with the presence of anti-ganglionic acetylcholine receptor (gAChR) antibodies; however, several studies have reported that individual
Externí odkaz:
https://doaj.org/article/399277845a9f4c39bab17fb72b5506a5
Autor:
Eiji Matsuura, Satoshi Nozuma, Mika Dozono, Daisuke Kodama, Masakazu Tanaka, Ryuji Kubota, Hiroshi Takashima
Publikováno v:
Pathogens, Vol 12, Iss 4, p 592 (2023)
Human T-cell leukemia virus-1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a slowly progressive neurological disease that arises from HTLV-1 infection. Pathologically, the condition is characterized by diffuse myelitis, wh
Externí odkaz:
https://doaj.org/article/08f6406651d84d779f33a6c16b2ff4f0