Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Masakazu Kotoda"'
Autor:
Kazuha Mitsui, Sohei Hishiyama, Aakanksha Jain, Yumi Kotoda, Masako Abe, Takashi Matsukawa, Masakazu Kotoda
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-10 (2023)
Abstract Background Postoperative pain and inflammation are significant complications following surgery. Strategies that aim to prevent excessive inflammation without hampering natural wound-healing are required for the management of postoperative pa
Externí odkaz:
https://doaj.org/article/82f930c5b6eb48f58473d5b79fd0d863
Autor:
Hiroki Kobayashi, Nobumasa Asano, Daisuke Kondo, Noriyuki Shintani, Masakazu Kotoda, Toru Matsuoka, Tadahiko Ishiyama, Takashi Matsukawa
Publikováno v:
BMC Anesthesiology, Vol 22, Iss 1, Pp 1-7 (2022)
Abstract Background With recent advances in robot-assisted techniques, an increasing number of surgeries are being performed with pneumoperitoneum and head-down maneuver (HDM) that may affect the cerebral microcirculation. For the first time, this st
Externí odkaz:
https://doaj.org/article/bdf7e75bd34b496fb071a1b779ba5ec1
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Shivering after surgery or during therapeutic hypothermia can lead to serious complications, such as myocardial infarction and respiratory failure. Although several anesthetics and opioids are shown to have anti-shivering effects, their sedative and
Externí odkaz:
https://doaj.org/article/90cfd2eda9be47d89d62c13e62b95157
Autor:
Masakazu Kotoda, Toru Matsuoka, Keiichi Wada, Selwyn Jayakar, Hirofumi Ino, Koji Kawago, Yasutomo Kumakura
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Local anesthetics with long-lasting effects and selectivity for nociceptors have been sought over the past decades. In this study, we investigated whether amiodarone, a multiple channel blocker, provides long-lasting local anesthesia and whether addi
Externí odkaz:
https://doaj.org/article/2c29e7eeacc24ad68af9b5e2d7bcf249
Autor:
Ayasa Takamino, Masakazu Kotoda, Yosuke Nakadate, Sohei Hishiyama, Tetsuya Iijima, Takashi Matsukawa
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2022)
As the world is rapidly aging, and the number of elderly patients who undergo surgery is rising, postoperative cognitive decline among those patients has become an increasing healthcare problem. Although understanding the risk factors and mechanisms
Externí odkaz:
https://doaj.org/article/a04f5f6808ab4034bc08d80d5e4ab910
Publikováno v:
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-7 (2020)
Abstract Background Although recent studies using experimental models of ischemic brain injury indicate that systemically-administered β1-blockers have potential protective effects on the cerebrovascular system, the precise mechanisms remain unclear
Externí odkaz:
https://doaj.org/article/ef9cee4feb934ba1a877872b3798d444
Publikováno v:
BMC Neuroscience, Vol 20, Iss 1, Pp 1-7 (2019)
Abstract Background Sodium ion transportation plays a crucial role in the pathogenesis of hypoxic–ischemic brain injury. Amiodarone, a Vaughan-Williams class III antiarrhythmic drug, has been widely used to treat life-threatening arrhythmia and car
Externí odkaz:
https://doaj.org/article/a8399d970ec24e2393ba61f87c8535da
Autor:
Kanae Tanabe, Masakazu Kotoda, Daiki Nakashige, Kazuha Mitsui, Kodai Ikemoto, Takashi Matsukawa
Publikováno v:
JA Clinical Reports, Vol 5, Iss 1, Pp 1-4 (2019)
Abstract Background Involuntary muscle contraction caused by extracardiac stimulation is a rare complication induced by a pacemaker. We report a case who developed sudden onset diaphragmatic contractions during general anesthesia caused by a DDD mode
Externí odkaz:
https://doaj.org/article/a4105bc3c8624d4fb4cbb1cdc26ec726
Autor:
Toru Matsuoka, Tadahiko Ishiyama, Noriyuki Shintani, Masakazu Kotoda, Kazuha Mitsui, Takashi Matsukawa
Publikováno v:
BMC Anesthesiology, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background We evaluated the change of cerebral regional tissue oxygen saturation (rSO2) along with the pneumoperitoneum and the Trendelenburg position. We also assessed the relationship between the change of rSO2 and the changes of mean arte
Externí odkaz:
https://doaj.org/article/554e125027ab4318b6d30a30a8c95651
Autor:
Seungkyu Lee, Sooyeon Jo, Sébastien Talbot, Han-Xiong Bear Zhang, Masakazu Kotoda, Nick A Andrews, Michelino Puopolo, Pin W Liu, Thomas Jacquemont, Maud Pascal, Laurel M Heckman, Aakanksha Jain, Jinbo Lee, Clifford J Woolf, Bruce P Bean
Publikováno v:
eLife, Vol 8 (2019)
Voltage-dependent sodium and calcium channels in pain-initiating nociceptor neurons are attractive targets for new analgesics. We made a permanently charged cationic derivative of an N-type calcium channel-inhibitor. Unlike cationic derivatives of lo
Externí odkaz:
https://doaj.org/article/de64bb25275445b0a3e4407fe3462af5