Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Masakazu Hayashibara"'
Autor:
Masakazu Hayashibara, Hiroshi Takane, Kenji Otsubo, Yoshikazu Shiinoki, Tatsuya Kaneda, Seiji Otani
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 37:187-193
To ensure the proper use of drugs,pharmacists must pay attention to drug incompatibility information.However,drug incompatibilityinformation relating to tablets or capsules in one-dose packages (DII) is not well understood.Therefore,weactively collec
Autor:
Masakazu Hayashibara, Hannosuke Wakushima, Eiji Hata, Kazuyo Hosokawa, Tatsuya Kaneda, Yoshikazu Shiinoki, Kenji Otubo, Kei Teramoto, Yasuko Tanabe
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 33:719-724
Autor:
Shigeru Ohmori, Kohsuke Mamiya, Kenji Otsubo, Hitoshi Tainaka, Nobutada Tashiro, Hideaki Ninomiya, Masakazu Hayashibara, T. Morita, Shun Higuchi, Ichiro Ieiri, Atsuko Hadama, Mitsukazu Kitada
Publikováno v:
Therapeutic Drug Monitoring. 22:237-244
This study evaluated the catalytic activity of three variants (Ile, Leu, and Thr) at codon 359 of CYP2C9 enzymes expressed in a yeast cDNA expression system, and then established single-strand conformation polymorphism (PCR-SSCP) analysis for simulta
Publikováno v:
Japanese Journal of Hospital Pharmacy. 24:237-242
Publikováno v:
Japanese Journal of Hospital Pharmacy. 20:131-138
To clarify the effect of plasma albumin on the salivary excretion of mexiletine, we have investigated the kinetics of and correlation between plasma and saliva levels following bolus intravenous administration (5 mg/kg) in male Sprague-Dawley rats (a
Autor:
Masakazu Hayashibara, Shigefumi Morioka, Katsutoshi Moriyama, Sadao Nagasako, Yoshihiro Katagiri, Kikuo Iwamoto
Publikováno v:
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 24:425-431
In order to investigate the utility of therapeutic monitoring of mexiletine aided by the saliva drug levels, serum (total and unbound fraction) and saliva drug concentrations were measured in six inpatients with ventricular arrhythmia who were given
Autor:
Masakazu Hayashibara, Sadao Nagasako, You Kusase, Kikuo Iwamoto, Naomi Kawabata, Akihiko Ishimura, Hidenari Hirano
Publikováno v:
Japanese Journal of Hospital Pharmacy. 19:328-333
Propylthiouracil (PTU), an antithyroid drug, has been widely used to treat hyperthyroidism. Since any dosage form other than tablet form is not commercially available for PTU, it is necessary to prepare the powder by pulverizing the tablet when dose
Publikováno v:
Journal of Pharmacy and Pharmacology. 42:704-707
The change in plasma concentration-time profile, serum protein binding and renal and biliary clearances of ciprofloxacin caused by coadministration of fenbufen has been studied in rats administered an intravenous dose of ciprofloxacin (5 mg kg−1) a
Autor:
Masakazu Hayashibara, Kikuo Iwamoto, Tadanori Itakura, Yasuhiro Kanba, Yoshihiro Katagiri, Kazuhide Mabuchi
Publikováno v:
Japanese Journal of Hospital Pharmacy. 16:260-268
The morphine hydrochloride suppository (MoS) containing sodium caprate (CA-MoS) or.sodium 5-methoxysalicylate (MS-MoS) was studied physicochemically and biopharmaceutically.The hardness and melting point of such suppository freshly prepared or stored
Publikováno v:
Journal of Pharmacobio-Dynamics. 13:90-96
In order to clarify the possibility of pharmacokinetic interaction between quinolone and fenbufen, the plasma concentration-time profiles and serum protein binding of enoxacin, fenbufen and its active metabolite, felbinac, were investigated in rats.