Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Masaji Ohno"'
Autor:
Gabor Lukacs, Masaji Ohno
The use of antibiotics in the treatment by antibacterial and antifungal chemo therapy, has become standard practice since the end of World War Two and has had an enormous impact on healthcare throughout the world. Compounds belonging to this class
Autor:
Susumu Kobayashi, Masato Yoshioka, Imai Nobuyuki, Hideyo Takahashi, Masaji Ohno, Masakatsu Shibasaki
Publikováno v:
Tetrahedron. 51:12013-12026
The first catalytic, enantioselective Simmons-Smith cyclopropanation of an allylic alochol has been achieved by the reaction of an allylic alcohol with Et 2 Zn and CH 2 I 2 in the presence of a catalytic amount of chiral disulfonamide 1 .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::540a7238e8a744e79840f2e1eb377f4a
https://doi.org/10.1016/0040-4020(95)00760-6
https://doi.org/10.1016/0040-4020(95)00760-6
Publikováno v:
Journal of the American Chemical Society. 116:3290-3295
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4213e3d958c4372c5c61b8014071685
https://doi.org/10.1021/ja00087a015
https://doi.org/10.1021/ja00087a015
Autor:
Masakatsu Shibasaki, Yukio Sugiura, Masami Otsuka, Toru Sugiyama, Masaji Ohno, Susumu Kobayashi, Kenji Maeda
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:705-710
Structure-function study on the β-aminoalaninamide moiety of bleomycin models revealed that the axial amino group is essential for efficient oxygen activation. Treatment of a model PYML-6 with mouse liver extract resulted in the hydrolysis of the ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5888796142c3fe723c67388021418290
https://doi.org/10.1016/s0960-894x(01)80184-0
https://doi.org/10.1016/s0960-894x(01)80184-0
Publikováno v:
Tetrahedron Letters. 35:741-744
The diastereoselectivity of nucleophilic addition to β-chiral acylsilanes is examined, and our method is applied to the stereoselective synthesis of calcitriol lactone, a major metabolite of vitamine D 3 .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c900a6ddd40369111afeb3d9657a3e6d
https://doi.org/10.1016/s0040-4039(00)75805-9
https://doi.org/10.1016/s0040-4039(00)75805-9
Publikováno v:
Ullmann's Encyclopedia of Industrial Chemistry
Antibiotics can be defined as chemical substances capable of inhibiting the growth of microorganisms. In the past decades, numerous compounds possessing various biological activities have been discovered. Antibiotics can be of microbial origin, semis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6d0092ef3b4270b4b6a6ed481a92745
https://doi.org/10.1002/14356007.a02_467.pub3
https://doi.org/10.1002/14356007.a02_467.pub3
Publikováno v:
Tetrahedron Letters. 34:1035-1038
The construction in optically pure form of the key building blocks, arising from our retrosynthetic analysis of the antitumor macrolide rhizoxin is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a94d143cf1e79928e788b8ceefc94c5
https://doi.org/10.1016/s0040-4039(00)77485-5
https://doi.org/10.1016/s0040-4039(00)77485-5
Publikováno v:
Tetrahedron Letters. 34:1039-1042
The first total synthesis of the antitumor macrolide, rhizoxin in a highly stereocontrolled manner is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7853f5c7235d9a8fc5a608e51d6fd939
https://doi.org/10.1016/s0040-4039(00)77486-7
https://doi.org/10.1016/s0040-4039(00)77486-7
Publikováno v:
Tetrahedron Letters. 34:665-668
An alternative and plausible mechanism is proposed for the reaction pathway of Meinwald rearrangement of electron deficient systems. This new reaction pathway involves α-lactone-type intermediate which is formed by intramolecular Michael addition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e5136a084b3734bf84282b01a5a1383
https://doi.org/10.1016/s0040-4039(00)61647-7
https://doi.org/10.1016/s0040-4039(00)61647-7
Publikováno v:
ChemInform. 22
Gallium compounds were utilized in organic synthesis for the first time. Dimethylgallium chloride and dimethylgallium triflate was found to efficiently promote the glycosidation using several glycopyranosyl fluorides.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d357d12515334dab02bfcad41f915886
https://doi.org/10.1002/chin.199107236
https://doi.org/10.1002/chin.199107236