Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Masaji Ishi"'
Autor:
Osamu Yamaguchi, Masaji Ishi, Yasushi Naganuma, Michiharu Matsuda, Ryosuke Momma, Katsuyuki Dairaku, Yang Suran, Kan Sasaki, Yasushi Onuma, Takeru Akabane, Nariyuki Mura, Yasuhiro Urayama, Daichi Ohta, Taku Nakajima, Juji Ito, Takashi Furukawa, Ryusuke Honma, Junichirou Shibuya, Tomohiro Uno, Takahiro Miyaji, Yuya Takakubo, Hiroyuki Tsuchida, Michiaki Takagi, Keiji Masuda, Yasuo Goto, Hanqing Huang, Hiroharu Oki, Akiko Sasaki, Ken Ogura, Yumiko Kanauchi, Atsushi Noro, Shouta Okuda, Shinji Kobayashi, Shinichi Goto, Takeshi Nakamura, Kenji Takenouchi, Takaaki Nagase
Publikováno v:
Journal of bone and mineral metabolism. 39(4)
Atypical femoral fractures (AFFs) have been correlated with long-term use of bisphosphonates (BPs), glucocorticoids (GCs), and femoral geometry. We investigated the incidence and characteristics of subtrochanteric (ST) and diaphyseal (DP) AFFs in all
Autor:
Ken Hiragami, Osamu Yamaguchi, Juji Ito, Michiaki Takagi, Takeru Akabane, Takashi Furukawa, Shinji Kobayashi, Masaji Ishi, Hiroyuki Tsuchida, Nariyuki Mura, Taku Nakajima, Kan Sasaki, Yasuhiro Urayama, Akiko Sasaki, Shouta Okuda, Michiharu Matsuda, Katsuyuki Dairaku, Junichirou Shibuya, Tsuneo Konta, Daichi Ohta, Yuya Takakubo, Tomohiro Uno, Yasuo Goto, Yasushi Onuma, Mitsuyoshi Seino, Keiji Masuda, Ken Ogura, Yumiko Kanauchi, Hiroharu Oki, Kenji Takenouchi, Yasushi Naganuma, Takeshi Nakamura, Shinichi Goto
Publikováno v:
The Tohoku journal of experimental medicine. 242(4)
Atypical femoral fractures (AFFs) have been reported to occur with minimal or spontaneous subtrochanteric and femoral shaft fractures with a characteristic transverse pattern, compared with typical femoral fractures in young patients with high-energy
Autor:
Yuya Takakubo, Daichi Ohta, Masaji Ishi, Juji Ito, Hiroharu Oki, Yasushi Naganuma, Tomohiro Uno, Akiko Sasaki, Takeru Akabane, Katsuyuki Dairaku, Shinichi Goto, Yasuo Goto, Yumiko Kanauchi, Shinji Kobayashi, Taku Nakajima, Keiji Masuda, Michiharu Matsuda, Nariyuki Mura, Kenji Takenouchi, Hiroyuki Tsuchida
Publikováno v:
Tohoku Journal of Experimental Medicine; Aug2017, Vol. 242 Issue 4, p327-334, 8p
Autor:
Takashi Sasaki, Moeko Mita, Naho Ikari, Ayane Kuboyama, Shuzo Hashimoto, Tatsuya Kaneko, Masaji Ishiguro, Makoto Shimizu, Jun Inoue, Ryuichiro Sato
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179226 (2017)
TGR5, a member of the G protein-coupled receptor (GPCR) family, is activated by bile acids. Because TGR5 promotes energy expenditure and improves glucose homeostasis, it is recognized as a key target in treating metabolic diseases. We previously show
Externí odkaz:
https://doaj.org/article/c49ab6b0817040e490694a029bf30fe7
Publikováno v:
Journal of Pharmacological Sciences, Vol 113, Iss 1, Pp 57-65 (2010)
The present study was designed to examine the binding affinity and functional potency of selective angiotensin II type 1 (AT1)-receptor antagonists towards specific mutants of AT1 receptor using site-directed mutagenesis. We also compared our results
Externí odkaz:
https://doaj.org/article/64c0c3d822754811aade95eeaf49bc2a
Autor:
Yuko Nagaoka, Maruf Ahmed, Murad Hossain, Mohiuddin Ahmed Bhuiyan, Masaji Ishiguro, Takashi Nakamura, Masatomo Watanabe, Takafumi Nagatomo
Publikováno v:
Journal of Pharmacological Sciences, Vol 106, Iss 1, Pp 114-120 (2008)
Computer simulations of the human α 1d-adrenergic receptor (α 1d-AR) based on the crystal structure of rhodopsin have been combined with experimental site-directed mutagenesis to investigate the role of residues in the transmembrane domains in anta
Externí odkaz:
https://doaj.org/article/4a857321d7bc484782b37c71a472bfd9
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126921 (2015)
Among proteins utilized as sweeteners, neoculin and miraculin are taste-modifying proteins that exhibit pH-dependent sweetness. Several experiments on neoculin have shown that His11 of neoculin is responsible for pH dependence. We investigated the mo
Externí odkaz:
https://doaj.org/article/a843986fab8d45c3a18de7c27df87407
Autor:
Maruf Ahmed, Habib Abul Muntasir, Murad Hossain, Masaji Ishiguro, Tadazumi Komiyama, Ikunobu Muramatsu, Hitoshi Kurose, Takafumi Nagatomo
Publikováno v:
Journal of Pharmacological Sciences, Vol 102, Iss 2, Pp 167-172 (2006)
We obtained a new mutant of the β1-adrenergic receptor (β1-AR) by point mutations that can constitutively activate β1-AR. Aspartate104 of the β1-AR in the 2nd transmembrane was replaced with alanine. The β1-AR mutant expressed in human embryonic
Externí odkaz:
https://doaj.org/article/3d634c84f06347f5abb44f6077455725
Autor:
Habib Abul Muntasir, Mohiuddin Ahmed Bhuiyan, Masaji Ishiguro, Masanobu Ozaki, Takafumi Nagatomo
Publikováno v:
Journal of Pharmacological Sciences, Vol 102, Iss 2, Pp 189-195 (2006)
Mutations producing constitutively active G-protein coupled receptors have been found in the pathophysiology of several diseases, implying that inverse agonists at the constitutively active receptors may have preferred therapeutic applications. Becau
Externí odkaz:
https://doaj.org/article/89c41733033a43e4a3430afc5334d2c2
Autor:
Katsuyoshi Masuda, Ayako Koizumi, Ken-ichiro Nakajima, Takaharu Tanaka, Keiko Abe, Takumi Misaka, Masaji Ishiguro
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35380 (2012)
One of the most distinctive features of human sweet taste perception is its broad tuning to chemically diverse compounds ranging from low-molecular-weight sweeteners to sweet-tasting proteins. Many reports suggest that the human sweet taste receptor
Externí odkaz:
https://doaj.org/article/7f4ae56ef4a74553a0a186d7071dbcce