Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Masahito Uemura"'
Autor:
Masahito Uemura, Yoshihiro Fujimura, Saiho Ko, Masanori Matsumoto, Yoshiyuki Nakajima, Hiroshi Fukui
Publikováno v:
International Journal of Hepatology, Vol 2011 (2011)
The liver plays a central role in hemostasis by synthesizing clotting factors, coagulation inhibitors, and fibrinolytic proteins. Liver cirrhosis (LC), therefore, impacts on both primary and secondary hemostatic mechanisms. ADAMTS13 is a metalloprote
Externí odkaz:
https://doaj.org/article/e08ad283cd1a4e9ca1ed87e90922abf6
Publikováno v:
Digestive Diseases and Sciences. 57:1144-1151
Over-proliferation and bacterial translocation of Gram-negative bacilli within the intestinal flora, and increased portal venous levels of endotoxins, are involved in nonalcoholic steatohepatitis (NASH).To evaluate the innate immune response in the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a302c0fbe408945563aecab7cb4e08
https://doi.org/10.1007/s10620-012-2073-z
https://doi.org/10.1007/s10620-012-2073-z
Autor:
Hiroshi Fukui, Chie Morioka, Masanori Matsumoto, Yuji Hori, Masahito Uemura, Masao Fujimoto, Hideto Kawaratani, Masahisa Toyohara, Tatsuhiro Tsujimoto, Seiji Kato, Hiroaki Takaya, Hiromichi Ishizashi, Norio Kurumatani, Tomomi Matsuyama, Yoshihiro Fujimura
Publikováno v:
Hepatology Research. 42:459-472
Aim: Decreased plasma ADAMTS13 activity (ADAMTS13:AC) results in accumulation of unusually large von Willebrand factor multimers and platelet thrombi formation. Our aim was to evaluate whether ADAMTS13:AC is a prognostic marker in patients with liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a7dd41a1eff1cc57682f9e8a59bb765
https://doi.org/10.1111/j.1872-034x.2011.00950.x
https://doi.org/10.1111/j.1872-034x.2011.00950.x
Autor:
Osamu Yokosuka, Yasukiyo Sumino, Hiroshi Fukui, Masahito Uemura, Satoshi Mochida, Hitoshi Maruyama, Kiwamu Okita, Yoshiyuki Narahara, Yasushi Matsuzaki, Choitsu Sakamoto, Hidenori Kanazawa, Naohiko Masaki, Shigehiro Kokubu
Publikováno v:
Journal of Gastroenterology. 47:313-320
Treatment with terlipressin and albumin has been reported recently to be effective in improving renal function in the treatment of cirrhotic patients with hepatorenal syndrome (HRS). The aim of this prospective, multicenter study was to investigate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a68d62d569357700cc68b7f83947d8
https://doi.org/10.1007/s00535-011-0485-8
https://doi.org/10.1007/s00535-011-0485-8
Autor:
Masahito Uemura, Hitoshi Yoshiji, Hideto Kawaratani, Toshiyuki Kitazawa, Hiroshi Fukui, Tatsuhiro Tsujimoto
Publikováno v:
Journal of Gastroenterology and Hepatology. 26:775-783
Background and Aim: Inflammatory cytokines, such as tumor necrosis factor-α (TNF-α) and interferon-gamma (IFN-γ), induce liver injury in the rat alcoholic liver disease (ALD) model. Y-40138 is known to suppress the pro-inflammatory cytokines and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1fe909a5b0ec6478be9fb4a7735bd67
https://doi.org/10.1111/j.1440-1746.2011.06658.x
https://doi.org/10.1111/j.1440-1746.2011.06658.x
Autor:
Hiroshi Fukui, Chie Morioka, Masahisa Toyohara, Ryuichi Noguchi, Hideto Kawaratani, Junichi Yamao, Yusaku Shirai, Kosuke Kaji, Masao Fujimoto, Hitoshi Yoshiji, Masahito Uemura, Tatsuhiro Tsujimoto, Akira Mitoro, Motoyuki Yoshida, Yosuke Aihara, Yasuhide Ikenaka, Masayoshi Sawai
Publikováno v:
Oncology Letters. 2:69-73
The identification of biomarkers of anti-angiogenic therapy that predict clinical benefit is of vital importance. We previously reported that a combination treatment with clinically available safe agents, specifically angiotensin-converting enzyme in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91199d6305378bc9adc84718a9fa0e46
https://doi.org/10.3892/ol.2010.196
https://doi.org/10.3892/ol.2010.196
Autor:
Yoshihiro Fujimura, Masahito Uemura, Yoshiyuki Nakajima, Hiroshi Fukui, Masanori Matsumoto, Saiho Ko
Publikováno v:
International Journal of Hematology. 91:20-29
The liver is a major source of clotting and fibrinolytic proteins, and plays a central role in thrombo-regulation. Patients with advanced liver diseases tend to bleed because of reduced plasma levels of several clotting factors and thrombocytopenia,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ffc4b63c1b24a9c45949efb6afc34e6
https://doi.org/10.1007/s12185-009-0481-4
https://doi.org/10.1007/s12185-009-0481-4
Autor:
Kosuke Kaji, Masao Fujimoto, Yasuhide Ikenaka, Hitoshi Yoshiji, Masahito Uemura, Mitsuteru Kitade, Hideto Kawaratani, Hiroshi Fukui, Tatsuhiro Tsujimoto, Akira Mitoro, Masaharu Yamazaki, Motoyuki Yoshida, Masayoshi Sawai, Masahisa Toyohara, Ryuichi Noguchi, Junichi Yamao
Publikováno v:
Journal of Hepatology. 51:315-321
Background/Aims No chemopreventive agent has been approved against hepatocellular carcinoma (HCC) yet. Since neovascularization plays a pivotal role in HCC, an angiostatic agent is considered as one of the promising approaches. The aim of this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5384be2956b2ddb74bde7986032e05ab
https://doi.org/10.1016/j.jhep.2009.04.011
https://doi.org/10.1016/j.jhep.2009.04.011
Autor:
Masanori Matsumoto, Yoshihiko Saito, Tamio Nakajima, Yoshihiro Fujimura, Masahito Uemura, Hiromichi Ishizashi, Manabu Horii, Keiichi Imagawa, Shiro Uemura, Yukiji Takeda, Hiroyuki Kawata, Hajime Iwama
Publikováno v:
Heart and Vessels. 23:301-307
The aim of the present study is to clarify the roles of circulating ADAMTS13 and von Willebrand factor (VWF) in the formation of coronary artery thrombi in acute myocardial infarction (AMI). Twenty-six AMI patients, 37 age-matched healthy controls, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69fa11444f7c2ca51e2c73fe29e3331
https://doi.org/10.1007/s00380-008-1053-x
https://doi.org/10.1007/s00380-008-1053-x
Autor:
Tomomi Matsuyama, Tatsuhiro Tsujimoto, Masahito Uemura, Hitoshi Yoshiji, Yoshihiro Fujimura, Hiroshi Fukui, Hiromichi Ishizashi, Chie Morioka, Masao Fujimoto, Seiji Kato, Masatoshi Ishikawa, Masanori Matsumoto
Publikováno v:
Current Drug Abuse Reviewse. 1:188-196
Alcoholic hepatitis (AH) is a potentially life-threatening complication of alcohol abuse. The severe form of AH, severe alcoholic hepatitis (SAH), is characterized by multiorgan failure (MOF) with manifestations of acute hepatic failure and is associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edcc37f7da11151c33c92417932c39ff
https://doi.org/10.2174/1874473710801020188
https://doi.org/10.2174/1874473710801020188