Zobrazeno 1 - 10
of 502
pro vyhledávání: '"Masahiro UEDA"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The single-molecule tracking of transmembrane receptors in living cells has provided significant insights into signaling mechanisms, such as mobility and clustering upon their activation/inactivation, making it a potential screening method f
Externí odkaz:
https://doaj.org/article/b093a7ac064e47869a8382c982c9da65
Publikováno v:
Biophysics and Physicobiology, Vol 21 (2024)
Single-molecule imaging in living cells is an effective tool for elucidating the mechanisms of cellular phenomena at the molecular level. However, the analysis was not designed for throughput and requires high expertise, preventing it from reaching l
Externí odkaz:
https://doaj.org/article/4f36b47bbfa94f189a9e162e4fc815f1
Autor:
Tatsat Banerjee, Satomi Matsuoka, Debojyoti Biswas, Yuchuan Miao, Dhiman Sankar Pal, Yoichiro Kamimura, Masahiro Ueda, Peter N. Devreotes, Pablo A. Iglesias
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-24 (2023)
Abstract The plasma membrane is widely regarded as the hub of the numerous signal transduction activities. Yet, the fundamental biophysical mechanisms that spatiotemporally compartmentalize different classes of membrane proteins remain unclear. Using
Externí odkaz:
https://doaj.org/article/fc58346f19f04ff1a949c99660d2891f
Publikováno v:
Cell Structure and Function, Vol 48, Iss 2, Pp 145-160 (2023)
In eukaryotic motile cells, the active Ras (Ras-GTP)-enriched domain is generated in an asymmetric manner on the cell membrane through the excitable dynamics of an intracellular signaling network. This asymmetric Ras signaling regulates pseudopod for
Externí odkaz:
https://doaj.org/article/f7aa895b712642c68ddbbfacb2389233
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Eukaryotic cells exhibit random migration in the absence of extracellular directional cues. This random migration acts as basal motility for various migratory responses such as chemotaxis. The self-organization of random motility requires the interna
Externí odkaz:
https://doaj.org/article/fbcd236d1c5f435a95e2a93b457b72bf
Autor:
Tsunenori Ouchida, Haruka Maeda, Yuka Akamatsu, Megumi Maeda, Shinji Takamatsu, Jumpei Kondo, Ryo Misaki, Yoshihiro Kamada, Masahiro Ueda, Keiji Ueda, Eiji Miyoshi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Glycosylation of proteins and lipids in viruses and their host cells is important for viral infection and is a target for antiviral therapy. Hepatitis B virus (HBV) is a major pathogen that causes acute and chronic hepatitis; it cannot be cu
Externí odkaz:
https://doaj.org/article/ea7b853bd0b644768fccc02561a510b8
Cracking suppression by substrate preheating using an induction heater in directed energy deposition
Publikováno v:
Journal of Advanced Mechanical Design, Systems, and Manufacturing, Vol 17, Iss 3, Pp JAMDSM0039-JAMDSM0039 (2023)
The applications of wear resistant material coatings or claddings by directed energy deposition (DED) are rapidly increasing in industrial engineering fields. DED allows us the use of non-expensive substrate materials and add functional materials suc
Externí odkaz:
https://doaj.org/article/64b5f16414bc4aaa9c1f3e4447bf14c7
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Calcium acts as a second messenger to regulate many cellular functions, including cell motility. In Dictyostelium discoideum, the cytosolic calcium level oscillates synchronously, and calcium waves propagate through the cell population durin
Externí odkaz:
https://doaj.org/article/73569279e0c84e20b595c1709802abdf
Autor:
Kouki Kawakami, Masataka Yanagawa, Suzune Hiratsuka, Misaki Yoshida, Yuki Ono, Michio Hiroshima, Masahiro Ueda, Junken Aoki, Yasushi Sako, Asuka Inoue
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
GPCR kinases (GRKs) phosphorylate active-form G-protein-coupled receptors (GPCRs). Here, the authors reveal that Gq heterotrimer coupled with the angiotensin II type-1 receptor (AT1R) determines the GRK subtypes recruited to the complex in a microdom
Externí odkaz:
https://doaj.org/article/2972418817ce44418cfb4f56c2c2f962
Autor:
Yoichiro Kamimura, Masahiro Ueda
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Chemotaxis describes directional motility along ambient chemical gradients and has important roles in human physiology and pathology. Typical chemotactic cells, such as neutrophils and Dictyostelium cells, can detect spatial differences in chemical g
Externí odkaz:
https://doaj.org/article/afcfc1b9a31a4d2b8376dfdf1d180034