Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Masahiro Shiroo"'
Autor:
Jade L. Ross, Urszula Grabowska, Karen Fuller, Kevin M. Lawrence, Masahiro Shiroo, Timothy J. Chambers, Bertil Samuelsson
Publikováno v:
Bone. 145:115354
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2d9653df1b835d85cf32e09df2b33d6
https://doi.org/10.1016/j.bone.2020.115354
https://doi.org/10.1016/j.bone.2020.115354
Publikováno v:
Current opinion in drug discoverydevelopment. 8(5)
Cathepsin K is abundantly and selectively expressed in osteoclasts where it plays a critical role in bone degradation. Cathepsin K inhibitors are the first antiresorptive agents that prevent bone loss while allowing bone formation to continue, thereb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ff2b108a306a30510281b4f2d010dc1
https://pubmed.ncbi.nlm.nih.gov/16159024
https://pubmed.ncbi.nlm.nih.gov/16159024
Publikováno v:
European journal of immunology. 23(11)
In HPB-ALL T-cells the p59fyn tyrosine kinase is regulated by the CD45 phosphotyrosine phosphatase and plays a critical role in coupling the T cell receptor (TCR) to the generation of intracellular signals which include diacylglycerol (DAG) productio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211c04a3f37078823ed0ab7c6cc7ace4
https://pubmed.ncbi.nlm.nih.gov/8223875
https://pubmed.ncbi.nlm.nih.gov/8223875
Publikováno v:
Immunology today. 13(12)
CD45 is one of the most abundant transmembrane glycoproteins expressed on the surface of haematopoietic cells. Despite the striking advances of the past few years in the understanding of the actions of CD45 at a molecular level, several paradoxes rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d6661d8c5349672350d9b3d2b92bf93
https://pubmed.ncbi.nlm.nih.gov/1463579
https://pubmed.ncbi.nlm.nih.gov/1463579
Autor:
Mark Biffen, Masahiro Shiroo, Denis R. Alexander, Martin J. Glennie, Emer Shivnan, Edward Pratt
Publikováno v:
European journal of immunology. 22(4)
The binding of agonistic monoclonal antibodies (mAb) to the CD3 antigen in T cells induces a rapid increase in tyrosine phosphorylation, inositive phosphate (IP) production, a rise in intracellular calcium and protein kinase C (PKC) activation. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417d3b41cbc220ede9e7a04d5a26b4bf
https://pubmed.ncbi.nlm.nih.gov/1532359
https://pubmed.ncbi.nlm.nih.gov/1532359
Publikováno v:
Scandinavian Journal of Immunology. 26:709-716
The homogenates of amyloid-laden spleens prepared from CBA mice were analysed by SDS-PAGE and immunoblotting employing rat anti-murine monoclonal antibody, MSA 4-26. The results showed that the precursor of amyloid A protein (AA), serum amyloid A pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b9363c48bbee9956e680f0d16ce332
https://doi.org/10.1111/j.1365-3083.1987.tb02307.x
https://doi.org/10.1111/j.1365-3083.1987.tb02307.x
Publikováno v:
Biochemistry. 27:3765-3770
The authors have recently shown that glucocorticoids dramatically increase the number of interleukin 1 (IL 1) receptors on human peripheral blood mononuclear cells (PBMC) and that IL 1 selectively induces the phosphorylation of a cytosolic 65-kilodal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342a39c226d713fff0f161a1d7a0a865
https://doi.org/10.1021/bi00410a037
https://doi.org/10.1021/bi00410a037
Publikováno v:
Science. 232:227-229
Serum amyloid A protein (SAA) is a precursor for a major component of amyloid fibrils, which, upon deposition, cause secondary amyloidosis in diseases such as rheumatoid arthritis. In mice, SAA is encoded by at least three genes, which show diverse e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b39486109abdc28d2a559dc9f78e7088
https://doi.org/10.1126/science.3456645
https://doi.org/10.1126/science.3456645
Publikováno v:
Biochemical and biophysical research communications. 108(1)
The cytochrome P-450 (P-450sccII) and its reductase, NADPH-cytochrome reductase [EC 1.6.2.4], associated with conversion of progesterone to 4-androstene-3,17-dione, were extensively purified from pig testis microsomes. Higher lyase activity (turnover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f10caa4b10e26292c8568ce92193208
https://pubmed.ncbi.nlm.nih.gov/6816231
https://pubmed.ncbi.nlm.nih.gov/6816231