Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Masahiro Nogami"'
Autor:
Masahiro Nogami, Osamu Sano, Keiko Adachi-Tominari, Yoshika Hayakawa-Yano, Takako Furukawa, Hidehisa Iwata, Kazuhiro Ogi, Hideyuki Okano, Masato Yano
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Fused in sarcoma/translated in liposarcoma (FUS) is an RNA-binding protein, and its mutations are associated with neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), through the DNA damage stress response, aberrant stress granu
Externí odkaz:
https://doaj.org/article/2b687065eb9f47e9a3ee4713c74db58a
Autor:
Riku Sato, Megumi Kanai, Yukina Yoshida, Shiori Fukushima, Masahiro Nogami, Takeshi Yamaguchi, Norio Iijima, Kenneth Sutherland, Sanae Haga, Michitaka Ozaki, Kazuko Hamada, Toshiyuki Hamada
Publikováno v:
Cells, Vol 12, Iss 4, p 654 (2023)
While the suprachiasmatic nucleus (SCN) coordinates many daily rhythms, some circadian patterns of expression are controlled by SCN-independent systems. These include responses to daily methamphetamine (MAP) injections. Scheduled daily injections of
Externí odkaz:
https://doaj.org/article/1804f846b15c494f8834405e457120d1
Autor:
Masahiro Nogami, Mitsuru Ishikawa, Atsushi Doi, Osamu Sano, Takefumi Sone, Tetsuya Akiyama, Masashi Aoki, Atsushi Nakanishi, Kazuhiro Ogi, Masato Yano, Hideyuki Okano
Publikováno v:
Neurobiology of Disease, Vol 155, Iss , Pp 105364- (2021)
Summary: Fused in sarcoma/translated in liposarcoma (FUS) is a causative gene of amyotrophic lateral sclerosis (ALS). Mutated FUS causes accumulation of DNA damage and cytosolic stress granule (SG) formation, thereby motor neuron (MN) death. However,
Externí odkaz:
https://doaj.org/article/1410dd69c2fd495e97b6d914072ba267
Autor:
Tetsuya Akiyama, Naoki Suzuki, Mitsuru Ishikawa, Koki Fujimori, Takefumi Sone, Jiro Kawada, Ryo Funayama, Fumiyoshi Fujishima, Shio Mitsuzawa, Kensuke Ikeda, Hiroya Ono, Tomomi Shijo, Shion Osana, Matsuyuki Shirota, Tadashi Nakagawa, Yasuo Kitajima, Ayumi Nishiyama, Rumiko Izumi, Satoru Morimoto, Yohei Okada, Takayuki Kamei, Mayumi Nishida, Masahiro Nogami, Shohei Kaneda, Yoshiho Ikeuchi, Hiroaki Mitsuhashi, Keiko Nakayama, Teruo Fujii, Hitoshi Warita, Hideyuki Okano, Masashi Aoki
Publikováno v:
EBioMedicine, Vol 45, Iss , Pp 362-378 (2019)
Background: The characteristic structure of motor neurons (MNs), particularly of the long axons, becomes damaged in the early stages of amyotrophic lateral sclerosis (ALS). However, the molecular pathophysiology of axonal degeneration remains to be f
Externí odkaz:
https://doaj.org/article/09b1c2d9afee403f938bc1b807d2caa6
Autor:
Yoshika Hayakawa-Yano, Takako Furukawa, Tsuyoshi Matsuo, Takahisa Ogasawara, Masahiro Nogami, Kazumasa Yokoyama, Masato Yugami, Munehisa Shinozaki, Chihiro Nakamoto, Kenji Sakimura, Akihide Koyama, Kazuhiro Ogi, Osamu Onodera, Hirohide Takebayashi, Hideyuki Okano, Masato Yano
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 9/10/2024, Vol. 121 Issue 37, p1-11, 46p
Autor:
Toshio Tanaka, Tomohiro Kawamoto, Satoshi Endo, Samuel Aparicio, Michiko Tawada, Atsushi Nakanishi, Momoko Ohori, Douglas R. Cary, Masahiro Ito, Masahiro Nogami, Toshihiro Imaeda, Misa Iwatani, Shinsuke Araki, Shoichi Nakao, Yasuhiro Imaeda
Publikováno v:
Biochemical and Biophysical Research Communications. 523:795-801
The DEAD-box family of RNA helicases plays essential roles in both transcriptional and translational mRNA degradation; they unwind short double-stranded RNA by breaking the RNA-RNA interactions. Two DEAD-box RNA helicases, eukaryotic translation init
Autor:
Tsuyoshi Matsuo, Masato Yano, Masahiro Nogami, Kazuhiro Ogi, Hideyuki Okano, Osamu Sano, Takayuki Kamei, Keiko Adachi-Tominari
Publikováno v:
Biochemical and biophysical research communications. 566
Ferroptosis was recently defined as a novel type of programmed cell death depending on iron and lipid peroxidation. It is biologically different from other types of cell death such as apoptosis. While the involvement of ferroptosis in cancer, patient
Autor:
Fumiyoshi Fujishima, Jiro Kawada, Mitsuru Ishikawa, Hiroaki Mitsuhashi, Hideyuki Okano, Keiko Nakayama, Kensuke Ikeda, Mayumi Nishida, Shio Mitsuzawa, Rumiko Izumi, Matsuyuki Shirota, Ryo Funayama, Tomomi Shijo, Tetsuya Akiyama, Yasuo Kitajima, Shohei Kaneda, Masahiro Nogami, Hiroya Ono, Shion Osana, Yohei Okada, Naoki Suzuki, Takefumi Sone, Takayuki Kamei, Teruo Fujii, Satoru Morimoto, Ayumi Nishiyama, Masashi Aoki, Hitoshi Warita, Tadashi Nakagawa, Koki Fujimori, Yoshiho Ikeuchi
Publikováno v:
EBioMedicine
Background The characteristic structure of motor neurons (MNs), particularly of the long axons, becomes damaged in the early stages of amyotrophic lateral sclerosis (ALS). However, the molecular pathophysiology of axonal degeneration remains to be fu
Autor:
Masashi Aoki, Hideyuki Okano, Kazuhiro Ogi, Atsushi Nakanishi, Masato Yano, Atsushi Doi, Takefumi Sone, Osamu Sano, Tetsuya Akiyama, Mitsuru Ishikawa, Masahiro Nogami
Publikováno v:
Neurobiology of Disease, Vol 155, Iss, Pp 105364-(2021)
SUMMARYFused in sarcoma/translated in liposarcoma (FUS) is a causative gene of amyotrophic lateral sclerosis (ALS). Mutated FUS causes accumulation of DNA damage and cytosolic stress granule (SG) formation, thereby motor neuron (MN) death. However, k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b2ab17cc8d865005c7938985889ba5
https://doi.org/10.1101/2021.01.07.425798
https://doi.org/10.1101/2021.01.07.425798
Autor:
Yoshika Hayakawa-Yano, Masahiro Nogami, Atsushi Nakanishi, Kazumasa Miyamoto, Hideyuki Okano, Masato Yano
Publikováno v:
The Journal of Biological Chemistry
Microprocessor complex, including DiGeorge syndrome critical region gene 8 (DGCR8) and DROSHA, recognizes and cleaves primary transcripts of microRNAs (pri-miRNAs) in the maturation of canonical miRNAs. The study of DGCR8 haploinsufficiency reveals t