Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Masahiro Masada"'
Autor:
Tomio Okamura, Masashi Tawa, Ayman Geddawy, Takashi Shimosato, Hirotaka Iwasaki, Haruo Shintaku, Yuichi Yoshida, Masahiro Masada, Kazuya Shinozaki, Takeshi Imamura
Publikováno v:
Journal of Pharmacological Sciences, Vol 124, Iss 1, Pp 76-85 (2014)
Abstract.: Deficiency of tetrahydrobiopterin (BH4) in the vascular tissue contributes to endothelial dysfunction through reduced eNOS activity and increased superoxide anion (O2−) generation in the insulin-resistant state. We investigated the effec
Externí odkaz:
https://doaj.org/article/f1159cd23700444cb3ec2a36531b9a19
Publikováno v:
Journal of Pharmacological Sciences, Vol 96, Iss 4, Pp 401-405 (2004)
It is tempting to speculate that increased vasoconstriction and loss of endothelium-dependent vasodilation might be etiological factors of elevated blood pressure in the insulin-resistant state. Vascular contraction induced by angiotensin II and the
Externí odkaz:
https://doaj.org/article/b9905142ce3148b582d43a65453062d1
Publikováno v:
Journal of Pharmacological Sciences, Vol 91, Iss 3, Pp 187-191 (2003)
Although insulin-resistant states have been associated with endothelial dysfunction due to increased vascular oxidative stress, the underlying mechanisms are pooly understood. Recent experimental evidence suggests that tetrahydrobiopterin (BH4), the
Externí odkaz:
https://doaj.org/article/5de5eb4389ec4bc0b8ba54d919b088d4
Autor:
Yuichi Yoshida, Masashi Tawa, Ayman Geddawy, Takeshi Imamura, Tomio Okamura, Hirotaka Iwasaki, Takashi Shimosato, Masahiro Masada, Kazuya Shinozaki, Haruo Shintaku
Publikováno v:
Journal of Pharmacological Sciences, Vol 124, Iss 1, Pp 76-85 (2014)
Deficiency of tetrahydrobiopterin (BH4) in the vascular tissue contributes to endothelial dysfunction through reduced eNOS activity and increased superoxide anion (O2−) generation in the insulin-resistant state. We investigated the effects of atorv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb234ddcbd887f3d9a2761c219071e5
https://doi.org/10.1254/jphs.13178fp
https://doi.org/10.1254/jphs.13178fp
Autor:
Akira Nishiyama, Christopher S. Wilcox, Takashi Morikawa, Yoshio Konishi, Masahiro Masada, Noriyuki Okada, Masahito Imanishi, Isseki Maeda, Chizuko Kitabayashi, Nobuo Shirahashi
Publikováno v:
Journal of the Renin-Angiotensin-Aldosterone System, Vol 14 (2013)
Introduction: We have previously demonstrated the increased salt sensitivity of blood pressure (BP) in diabetic patients with early nephropathy. Here, we examined the effects of an angiotensin II receptor blocker (ARB) on salt sensitivity and renal o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0df0d008237365aa27ff900913a903a
https://doi.org/10.1177/1470320312454764
https://doi.org/10.1177/1470320312454764
Autor:
Shinji Kasai, Kentaro Itokawa, Osamu Komagata, Masahiro Masada, Takashi Tomita, Yoshika Okamura
Publikováno v:
Insect Biochemistry and Molecular Biology. 40:631-640
Development of insecticide resistance reduces the efficacy of controlling measures against the medical and agricultural insect pests. Cytochrome P450s are one of the major detoxification enzymes involved in insecticide metabolisms. Previously, we hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c7c2e93e27e66eed9d2466cf94e9f3
https://doi.org/10.1016/j.ibmb.2010.06.001
https://doi.org/10.1016/j.ibmb.2010.06.001
Publikováno v:
Pteridines, Vol 17, Iss 1, Pp 11-15 (2006)
Endothelial vasodilator dysfunction is a characteristic feature of patients at risk for coronary atheroscierosis. We have reported that insulin resistance may be a pathogenic factor for endothehal dysfunction through impaired endothelial nitric oxide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42a4e8f404fe51c21700f9df844c4b4a
https://doaj.org/article/05499053d0774b0eb8cd0a10be9851d8
https://doaj.org/article/05499053d0774b0eb8cd0a10be9851d8
Autor:
Masahiro Masada, Kazuya Shinozaki, Atsunori Kashiwagi, Daisuke Koya, Yuichi Yoshida, Yoshihiko Nishio, Tomio Okamura, Kazuhide Ayajiki
Publikováno v:
Journal of Cardiovascular Pharmacology. 46:505-512
Deficiency of tetrahydrobiopterin (BH 4 ) in the vascular tissue contributes to endothelial dysfunction in the insulin-resistant state. We intended to develop a new gene transfer method by overexpression of its biosynthetic enzyme, GTP cyclohydrolase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6562d2731135320c9d443021d1bd9d29
https://doi.org/10.1097/01.fjc.0000177981.91434.ba
https://doi.org/10.1097/01.fjc.0000177981.91434.ba
Publikováno v:
Plant Biotechnology. 21:73-77
In Spinacia oleacea, three isoforms of cysteine synthase (CSase, O-acetyl-serine (thiol) lyase) were identified in the cytosolic, plastidial, and mitochondorial compartments. Here, we report molecular cloning of a cDNA that encodes a CSase-like prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7134c8d9877d40b31341a2f96aff9089
https://doi.org/10.5511/plantbiotechnology.21.73
https://doi.org/10.5511/plantbiotechnology.21.73
Publikováno v:
Plant Molecular Biology Reporter. 21:21-30
We present a method for detecting spliced products from transiently expressed genes using an intron construct containing the target intron and neighboring short exons. The downstream exon was fused with theGUS reporter gene and inserted behind the ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a1c9eaef5b76ea3937835739dc8cc3f
https://doi.org/10.1007/bf02773393
https://doi.org/10.1007/bf02773393