Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Masahiro Ikesue"'
Autor:
Daisuke Fujikura, Masahiro Ikesue, Tsutomu Endo, Satoko Chiba, Hideaki Higashi, Toshimitsu Uede
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Germinal centre (GC) reactions are driven by T follicular helper (Tfh) cells and their dysregulation can cause autoimmune disease. Here the authors show that the orphan receptor DR6 is a Tfh cell marker that binds syndecan-1 on GC B cells driving aut
Externí odkaz:
https://doaj.org/article/3404813b4b0f4f73bb0e2305f7deb185
Autor:
Shiho Aoki, Atsushi Iwai, Koji Kawata, Daisuke Muramatsu, Hirofumi Uchiyama, Mitsuyasu Okabe, Masahiro Ikesue, Naoyoshi Maeda, Toshimitsu Uede
Publikováno v:
Journal of Functional Foods, Vol 18, Iss , Pp 22-27 (2015)
The Aureobasidium pullulans-produced β-glucan (AP-PG) is an immune stimulator, and believed to exhibit beneficial effects on health through its immune stimulating activity. Here, the effect of oral administration of AP-PG on high-fat diet (HFD)-indu
Externí odkaz:
https://doaj.org/article/f105abec77dc46d498a4ee1e7f9a35d3
Autor:
Tsutomu Endo, Satoko Chiba, Hideaki Higashi, Daisuke Fujikura, Toshimitsu Uede, Masahiro Ikesue
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Expansion of autoreactive follicular helper T (Tfh) cells is tightly restricted to prevent induction of autoantibody-dependent immunological diseases, such as systemic lupus erythematosus (SLE). Here we show expression of an orphan immune regulator,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4aa5c5458bbbc5085e6b208b40a78de
https://doaj.org/article/3404813b4b0f4f73bb0e2305f7deb185
https://doaj.org/article/3404813b4b0f4f73bb0e2305f7deb185
Autor:
Naoyoshi Maeda, Hirofumi Uchiyama, Toshimitsu Uede, Koji Kawata, Daisuke Muramatsu, Masahiro Ikesue, Shiho Aoki, Mitsuyasu Okabe, Atsushi Iwai
Publikováno v:
Journal of Functional Foods, Vol 18, Iss, Pp 22-27 (2015)
The Aureobasidium pullulans-produced β-glucan (AP-PG) is an immune stimulator, and believed to exhibit beneficial effects on health through its immune stimulating activity. Here, the effect of oral administration of AP-PG on high-fat diet (HFD)-indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9afddeb6d9ac65e21e7ce45f7a03917
http://hdl.handle.net/2115/63473
http://hdl.handle.net/2115/63473
Autor:
Daisuke Takahashi, Masahiro Ikesue, Junko Morimoto, Masashi Kanayama, Shigeyuki Kon, Toshimitsu Uede, Daichi Ota, Tsutomu Endo, Norimasa Iwasaki, Koyu Ito, Tomohiro Onodera
Publikováno v:
Arthritis & Rheumatology. 67:2512-2522
Objective Syndecan 4 has been implicated as a critical mediator of inflammatory responses because of its functions as a coreceptor and reservoir for growth factors and chemokines. Although syndecan 4 is known to be expressed on B cells, its role in i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b83bca0e627877103621f541461e9cea
https://doi.org/10.1002/art.39193
https://doi.org/10.1002/art.39193
Autor:
Yasue Fukushima, Masahiro Ikesue, Jiawei Li, Michio Nakanishi, Kosuke Endo, Takashi Asada, Yoichi Goto, Naoharu Iwai
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International
The environmental factors such as aging, smoking, and alcohol consumption have been reported to influence DNA methylation (DNAm). However, the versatility of DNAm measurement by DNAm array systems is low in clinical use. Thus, we developed the MethyL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb3b63c8767cd5886d2810ff7777575d
https://doi.org/10.1155/2015/451981
https://doi.org/10.1155/2015/451981
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2015 (2015)
BioMed Research International, Vol 2015 (2015)
MicroRNAs (miRNAs) are small noncoding RNAs of 18–23 nucleotides that regulate gene expression. Recently, plasma miRNAs have been investigated as biomarkers for various physiological and pathological conditions. The present study details the conser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e4c51593e484ea0950fc141d00e2dc4
https://doi.org/10.1155/2015/465479
https://doi.org/10.1155/2015/465479
Autor:
Toshimitsu Uede, Daichi Ota, Koyu Ito, Masahiro Ikesue, Ann F. Chambers, Yoshikazu Takada, Yutaka Matsui
Publikováno v:
American Journal of Immunology. 8:123-135
Increasing evidence suggests that a disintegrin and metalloproteinase 15 (ADAM15) have essential roles in the process of cancer metastasis via degradation of the extracellular matrix and binding to integrins. Among them, ADAM15 possesses an Arg-Gly-A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49cc45020cd50871d0e7fc6f0ce29537
https://doi.org/10.3844/ajisp.2012.123.135
https://doi.org/10.3844/ajisp.2012.123.135
Autor:
Shinya Tanaka, Keiko Danzaki, Yutaka Matsui, Junko Morimoto, Mami Sato, Masahiro Ikesue, Hiroyuki Tsutsui, Tetsuhito Kojima, Toshimitsu Uede
Publikováno v:
Circulation Research. 108:1328-1339
Rationale: Syndecan-4 (Syn4), a cell-surface heparan sulfate proteoglycan, has been detected in the infarct region after myocardial infarction (MI), but its functional significance has not been elucidated. Objective: We examined whether and how Syn4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a640980b3fbe872b69936c07fccfa1b
https://doi.org/10.1161/circresaha.110.235689
https://doi.org/10.1161/circresaha.110.235689
Autor:
Tsutomu, Endo, Koyu, Ito, Junko, Morimoto, Masashi, Kanayama, Daichi, Ota, Masahiro, Ikesue, Shigeyuki, Kon, Daisuke, Takahashi, Tomohiro, Onodera, Norimasa, Iwasaki, Toshimitsu, Uede
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 67(9)
Syndecan 4 has been implicated as a critical mediator of inflammatory responses because of its functions as a coreceptor and reservoir for growth factors and chemokines. Although syndecan 4 is known to be expressed on B cells, its role in immune resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f04fd4e1ca29efa7f5ef2cd97eae9bc9
https://pubmed.ncbi.nlm.nih.gov/25989265
https://pubmed.ncbi.nlm.nih.gov/25989265