Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Masahiro Amakawa"'
Autor:
Sakae Tanaka, Ryota Chijimatsu, Masahiro Amakawa, Hideki Nakamoto, Fumiko Yano, Yoshihide Miyake, Hiroyuki Yamanaka, Taku Saito, Yasutaka Murahashi, Toshihiko Yamashita, Kousuke Iba, Yuji Maenohara
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Osteoarthritis (OA) is one of the world’s most common degenerative diseases, but there is no disease-modifying treatment available. Previous studies have shown that prostaglandin E2 (PGE2) and PGE2 receptor 4 (EP4) are involved in OA pathogenesis;
Autor:
Masahiro Amakawa, Takahiko Murata, Takuji Tanaka, Yasushi Matsumura, Tango Handa, Koji Takeuchi, Yoshihide Miyake, Katsuhiko Konishi, Yusuke Watanabe
Publikováno v:
European Journal of Pharmacology. 754:179-189
Agonists for EP4 receptor, a prostaglandin E2 receptor subtype, appear to be a promising therapeutic strategy for ulcerative colitis (UC) due to their anti-inflammatory and epithelial regeneration activities. However, the clinical development of oral
Autor:
Ryosuke Fukui, Nobuyuki Negoro, Nakaaki Ohsawa, Masahiro Amakawa, Nobuhiko Shibata, Masaaki Hoshiga, Masaaki, Minoru Seto, Teruo Ueno, Takahiro Nakakoji, Yasuharu Sasaki, Eiko Kohbayashi, Futoshi Nishiguchi, Tadashi Ishihara
Publikováno v:
American Journal of Physiology-Cell Physiology. 279:C999-C1007
Migration and proliferation of smooth muscle cells (SMC) contribute to neointimal formation after arterial injury. However, the relation between migration and proliferation in these cells is obscure. To discriminate between migration and proliferatio
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1406:107-114
Dehydroepiandrosterone (DHEA) and its sulfate (DHEA-S) are the most abundant steroids in humans, and their serum concentrations progressively decrease with age. Although relationships between DHEA(-S) and many age-related illnesses have been postulat
Autor:
Masahiro Amakawa, Yasuhisa Endo
Publikováno v:
Archives of histology and cytology. 65(2)
We investigated the relationship between the motility of hepatic Ito cells and their myofibroblastic transformation in cultures. Ito cells were freshly isolated from rat liver and cultured in a 10% FBS-supplemented medium. On day 2 after beginning th
Autor:
Nobuyuki Negoro, Masahiro Amakawa, Nakaaki Ohsawa, Eiko Kohbayashi, Masaaki Hoshiga, Daisuke Furutama, Ryousuke Fukui, Takahiro Nakakouji, Masaaki, Tadashi Ishihara, Nobuhiko Shibata
Publikováno v:
Atherosclerosis. 132(1)
In vascular smooth muscle cells (SMCs), proliferation and migration contribute to lesion formation after arterial injury. In the cell cycle, several cyclin-dependent kinases (cdks) inhibitors are implicated in the regulating of cyclin-cdk activity su
Autor:
Mihoko Takami, Masahiro Amakawa, Tango Handa, Yoshihide Miyake, Yasushi Matsumura, Katsuhiko Konishi, Takahiko Murata
Publikováno v:
Gastroenterology. 140:S-517