Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Masahiro, Onji"'
Autor:
Masahiro Onji, Josef Penninger
Publikováno v:
Physiology (Bethesda, Md.).
Receptor activator of nuclear factor-κB (RANK) and its ligand (RANKL) are key regulators of mammalian physiology such as bone metabolism, immune tolerance and antitumor immunity, and mammary gland biology. Here, we explore the multiple functions of
Autor:
Ryutaro Fukui, Chikako Yamamoto, Fumi Matsumoto, Masahiro Onji, Takuma Shibata, Yusuke Murakami, Atsuo Kanno, Takuto Hayashi, Natsuko Tanimura, Nobuaki Yoshida, Kensuke Miyake
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Mouse toll-like receptor 9 (TLR9) is an endosomal sensor for single-stranded DNA. TLR9 is transported from the endoplasmic reticulum to endolysosomes by a multiple transmembrane protein Unc93 homolog B1, and proteolytically cleaved at its ectodomain.
Externí odkaz:
https://doaj.org/article/098608ff306f4bcd8e80e8f7fd73df85
Autor:
Masahiro Onji, Penninger, Josef M.
Publikováno v:
Physiology; May2023, Vol. 38 Issue 3, p110-124, 15p
Autor:
Teruya Nagahara, Masaya Iwamuro, Hiroyuki Okada, Daisuke Uchida, Hidenori Shiraha, Masahiro Onji
Publikováno v:
Journal of Biomaterials and Tissue Engineering. 9:171-179
Publikováno v:
EMBO Rep
EMBO Reports
EMBO Reports
Recent studies have unveiled unique functions of the bone marrow adipose tissue (BMAT), which represent over 10% of the total adipose tissue mass in healthy adults. Increasing evidence is emerging as to how BMAT deposition and osteoporosis are linked
Autor:
Sakuma Takahashi, Daisuke Kawai, Akinobu Takaki, Kazuhide Yamamoto, Yoshiyasu Kono, Hiroyuki Okada, Hisashi Ishikawa, Sayo Kobayashi, Yasuyuki Shimomura, Seiji Kawano, Masahiro Onji, Joichiro Horii
Publikováno v:
Journal of Gastroenterology and Hepatology. 32:136-145
Background and Aim Video-capsule endoscopy (VCE) has shown that intestinal ulcers are common in non-steroidal anti-inflammatory drugs (NSAIDs) users, although the mechanisms and management have not been clearly defined. To explore the contribution of
Autor:
Shane J. F. Cronin, Toshikatsu Hanada, Laura Mondragón, Peng Zhang, Valentina Sica, Tsung-Pin Pai, Guido Kroemer, Blanka Pranjic, Shuan Rao, Ivona Kozieradzki, Oliver Kepp, Josef M. Penninger, Daniel Schramek, Helmut Popper, Alexander Lercher, Alexander Jais, Zhigang She, Franz Quehenberger, Katharina Haigh, Nazanine Modjtahedi, Iris Uribesalgo, Andreas Bergthaler, Masahiro Onji, Thomas Köcher, Malgorzata Rak, Rubina Koglgruber, Lukas Kenner, Gautier Stoll, Marion Leduc, Jody J. Haigh, Reiko Hanada, Kaican Cai
Publikováno v:
Cell Research
Cell Research, Nature Publishing Group, 2019, 29 (7), pp.579-591. ⟨10.1038/s41422-019-0181-4⟩
Cell Res
Cell Research, Nature Publishing Group, 2019, 29 (7), pp.579-591. ⟨10.1038/s41422-019-0181-4⟩
Cell Res
International audience; Cancer is a major and still increasing cause of death in humans. Most cancer cells have a fundamentally different metabolic profile from that of normal tissue. This shift away from mitochondrial ATP synthesis via oxidative pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4daf646473a9eecb7d69a5b566f7dd
https://hal.archives-ouvertes.fr/hal-02355955
https://hal.archives-ouvertes.fr/hal-02355955
Autor:
Koji Miyahara, Kazuko Koike, Kazuhide Yamamoto, Akinobu Takaki, Jun Wada, Atsuko Nakatsuka, Fusao Ikeda, Masahiro Onji, Nozomu Wada, Tetsuya Yasunaka, Hidenori Shiraha, Hiroyuki Okada, Kazuhiro Nouso
Publikováno v:
Hepatology International. 11:115-124
The molecular pathogenesis of non-alcoholic steatohepatitis (NASH) is not well defined. The objective of the present study was to identify disease progression-related cytokines and investigate the molecular pathogenesis of such changes in NASH. A stu
Autor:
Yoshiyasu, Kono, Seiji, Kawano, Akinobu, Takaki, Yasuyuki, Shimomura, Masahiro, Onji, Hisashi, Ishikawa, Sakuma, Takahashi, Joichiro, Horii, Sayo, Kobayashi, Daisuke, Kawai, Kazuhide, Yamamoto, Hiroyuki, Okada
Publikováno v:
Journal of gastroenterology and hepatology. 32(1)
Video-capsule endoscopy (VCE) has shown that intestinal ulcers are common in non-steroidal anti-inflammatory drugs (NSAIDs) users, although the mechanisms and management have not been clearly defined. To explore the contribution of oxidative stress a
Autor:
Mitsuru Matsumoto, Shizuo Akira, Ryutaro Fukui, Nobuaki Yoshida, Morikazu Onji, Atsuo Kanno, Masahiro Onji, Kensuke Miyake, Shin-ichiroh Saitoh, Takuma Shibata, Akihiko Ito
Publikováno v:
Immunity. 35(1):69-81
Summary Toll-like receptor-7 (TLR7) and 9, innate immune sensors for microbial RNA or DNA, have been implicated in autoimmunity. Upon activation, TLR7 and 9 are transported from the endoplasmic reticulum (ER) to endolysosomes for nucleic acid sensing