Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Masahiro, Nagata"'
Autor:
Lucie Laurien, Masahiro Nagata, Hannah Schünke, Tom Delanghe, Janica L. Wiederstein, Snehlata Kumari, Robin Schwarzer, Teresa Corona, Marcus Krüger, Mathieu J. M. Bertrand, Vangelis Kondylis, Manolis Pasparakis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Receptor interacting protein kinase 1 (RIPK1) regulates cell death and inflammatory responses. Here the authors show that autophosphorylation at Ser166 is required for RIPK1-mediated cell death and inflammation in mouse models of inflammatory patholo
Externí odkaz:
https://doaj.org/article/2d82135048944fbfa5ea87adae76d9b0
Autor:
Huipeng Jiao, Laurens Wachsmuth, Simone Wolf, Juliane Lohmann, Masahiro Nagata, Göksu Gökberk Kaya, Nikos Oikonomou, Vangelis Kondylis, Manuel Rogg, Martin Diebold, Simon E. Tröder, Branko Zevnik, Marco Prinz, Christoph Schell, George R. Young, George Kassiotis, Manolis Pasparakis
Publikováno v:
Nature. 607:776-783
Mutations of theADAR1gene encoding an RNA deaminase cause severe diseases associated with chronic activation of type I interferon (IFN) responses, including Aicardi–Goutières syndrome and bilateral striatal necrosis1–3. The IFN-inducible p150 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6247c64365d24c9f5922dbcac23f6e57
https://doi.org/10.1038/s41586-022-04878-9
https://doi.org/10.1038/s41586-022-04878-9
Autor:
Sho Yamasaki, Shigenori Nagai, Ben J. Appelmelk, Shojiro Haji, Nobuyuki Okahashi, Koichi Takato, Akihiro Imamura, Spencer J. Williams, Makoto Arita, Tomofumi Miyamoto, Kenji Toyonaga, Yoshihiro Izumi, Masatomo Takahashi, Hideharu Ishida, Masahiro Nagata, Mattie S. M. Timmer, Petr A. Illarionov, Bridget L. Stocker, Dylan G.M. Smith, Eri Ishikawa, Takeshi Bamba
Publikováno v:
Nagata, M, Toyonaga, K, Ishikawa, E, Haji, S, Okahashi, N, Takahashi, M, Izumi, Y, Imamura, A, Takato, K, Hideharu Ishida, I, Nagai, S, Illarionov, P, Stocker, B L, Timmer, M S M, Smith, D G M, Williams, S J, Bamba, T, Miyamoto, T, Arita, M, Appelmelk, B J & Yamasaki, S 2021, ' Helicobacter pylori metabolites exacerbate gastritis through C-type lectin receptors ', Journal of Experimental Medicine, vol. 218, no. 1, e20200815 . https://doi.org/10.1084/JEM.20200815
Journal of Experimental Medicine, 218(1):e20200815. Rockefeller University Press
The Journal of Experimental Medicine
Journal of Experimental Medicine, 218(1):e20200815. Rockefeller University Press
The Journal of Experimental Medicine
Helicobacter pylori is a pathogenic bacterium causing gastritis and malignancy; however, the underlying mechanism is not fully understood. Nagata et al. purify and identify virulent metabolites of H. pylori modified from host lipid that exacerbate in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c567253ecee8c1a6b7d77e3e510dbe28
https://research.vumc.nl/en/publications/6f6ca592-309b-43f8-9055-37fea4c4a80d
https://research.vumc.nl/en/publications/6f6ca592-309b-43f8-9055-37fea4c4a80d
Publikováno v:
2020 23rd International Conference on Electrical Machines and Systems (ICEMS).
Ride comfort of regenerative brake in the electric vehicle is studied. Experiment device is consisted of the 3-phase synchronous motor, rotational load and the electrical double layer capacitor (EDLC) as the energy storage. The rotational load simula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::495b176b082d1a050261a52fa7374328
https://doi.org/10.23919/icems50442.2020.9290977
https://doi.org/10.23919/icems50442.2020.9290977
Publikováno v:
International Immunology. 30:233-239
Macrophage-inducible C-type lectin, better known as Mincle, is a member of the C-type lectin receptor family and is encoded by Clec4e. Mincle was an orphan receptor for a long time after having been discovered as a lipopolysaccharide-induced protein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1be2e03a4f25605fb7bc3574facd450
https://doi.org/10.1093/intimm/dxy028
https://doi.org/10.1093/intimm/dxy028
The innate immune receptor Mincle senses lipid-based molecules derived from pathogens, commensals and altered self. Based on emerging structure-activity relationships we design simple alkyl 6-O-acyl-b-D-glucosides that are effective agonists of Mincl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::976a4a3152eaa712ba92b71b508e5da2
https://doi.org/10.26434/chemrxiv.10567097
https://doi.org/10.26434/chemrxiv.10567097
Autor:
Mathieu J.M. Bertrand, Lucie Laurien, Snehlata Kumari, Teresa Corona, Masahiro Nagata, Robin Schwarzer, Vangelis Kondylis, Manolis Pasparakis, Janica L Wiederstein, Tom Delanghe, Hannah Schünke, Marcus Krüger
Publikováno v:
Nature Communications
NATURE COMMUNICATIONS
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
NATURE COMMUNICATIONS
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Receptor interacting protein kinase 1 (RIPK1) regulates cell death and inflammatory responses downstream of TNFR1 and other receptors, and has been implicated in the pathogenesis of inflammatory and degenerative diseases. RIPK1 kinase activity induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41256e08a051873af2b04d55e8c6a080
https://pubmed.ncbi.nlm.nih.gov/32269263
https://pubmed.ncbi.nlm.nih.gov/32269263
Autor:
Mattie S. M. Timmer, Amy J. Foster, Shou Yamasaki, Amy T. Lynch, Xiuyuan Lu, Masahiro Nagata, Bridget L. Stocker, Eri Ishikawa, Zakaria Omahdi
Publikováno v:
Journal of medicinal chemistry. 61(3)
Effective Th1-stimulating vaccine adjuvants typically activate antigen presenting cells (APCs) through pattern recognition receptors (PRRs). Macrophage inducible C-type lectin (Mincle) is a PRR expressed on APCs and has been identified as a target fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6b8bba68ed35c549a4a0d7e9626777e
https://pubmed.ncbi.nlm.nih.gov/29290115
https://pubmed.ncbi.nlm.nih.gov/29290115
Autor:
Jonas Aretz, Masahiro Nagata, Hendra S. Ismanto, Bernd Lepenies, Keiichi Yoshida, Kozui Kida, Takashi Angata, Tetsuya Hirayama, Shinobu Kitazume, Christoph Rademacher, Yasuhiko Kizuka, Tomoko Betsuyaku, Fumi Ota, Sho Yamasaki, Reiko Fujinawa, Naoyuki Taniguchi, Yoshiki Yamaguchi, Peter H. Seeberger
Publikováno v:
Biochimica et biophysica acta. General subjects. 1862(7)
Background Langerin, a C-type lectin receptor (CLR) expressed in a subset of dendritic cells (DCs), binds to glycan ligands for pathogen capture and clearance. Previous studies revealed that langerin has an unusual binding affinity toward 6-sulfated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614f1348d8099451ef587eb702e1d1c3
https://pubmed.ncbi.nlm.nih.gov/29631057
https://pubmed.ncbi.nlm.nih.gov/29631057
Autor:
Eri Ishikawa, Satoru Iwai, Yoshihiro Izumi, Zakaria Omahdi, Sho Yamasaki, Masahiro Nagata, Tomofumi Miyamoto, Toshiyuki Yamaji, Rieko Doi, Ryoko Kiyotake, Takeshi Bamba
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Sensing and reacting to tissue damage is a fundamental function of immune systems. Macrophage inducible C-type lectin (Mincle) is an activating C-type lectin receptor that senses damaged cells. Notably, Mincle also recognizes glycolipid ligands on pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aca2b20b2e473dbc9eb03b14a5efd499
https://doi.org/10.1073/pnas.1618133114
https://doi.org/10.1073/pnas.1618133114