Zobrazeno 1 - 10 of 236 pro vyhledávání: '"Masahiro, Kojima"'
1
Akademický článek
Adaptive design for identifying maximum tolerated dose early to accelerate dose-finding trial
Autor: Masahiro Kojima
Publikováno v: BMC Medical Research Methodology, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Purpose The early identification of maximum tolerated dose (MTD) in phase I trial leads to faster progression to a phase II trial or an expansion cohort to confirm efficacy. Methods We propose a novel adaptive design for identifying MTD earl
Externí odkaz: https://doaj.org/article/4c5053896f954f8499793fd2e8d91571
Zobrazit plný text záznamu
2
Akademický článek
Silane- and peroxide-free hydrogen atom transfer hydrogenation using ascorbic acid and cobalt-photoredox dual catalysis
Autor: Yuji Kamei, Yusuke Seino, Yuto Yamaguchi, Tatsuhiko Yoshino, Satoshi Maeda, Masahiro Kojima, Shigeki Matsunaga
Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Hydrogen atom transfer (HAT) hydrogenation of alkenes usually requires stoichiometric silanes and peroxides. Here, the authors report a silane- and peroxide-free HAT hydrogenation method using a combined cobalt/photoredox catalysis and vitamin C as a
Externí odkaz: https://doaj.org/article/a56081321b4f461bbcb59287a5d99175
Zobrazit plný text záznamu
5
Data-dependent early completion of dose-finding trials for drug-combination
Autor: Masahiro Kojima
Publikováno v: Statistical Methods in Medical Research. 32:820-828
Context summary I propose a data-dependent early completion of dose-finding trials for drug combinations. Early completion is determined when the dose retainment probability using both the trial data and the number of remaining patients is high. An e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d3052d437163316b35611a841cf5e68a
https://doi.org/10.1177/09622802231155094
Zobrazit plný text záznamu
7
Randomized, double-blind, placebo-controlled phase 3 study of bardoxolone methyl in patients with diabetic kidney disease: design and baseline characteristics of the AYAME study
Autor: Masaomi Nangaku, Hirotaka Takama, Tomohiro Ichikawa, Kazuya Mukai, Masahiro Kojima, Yusuke Suzuki, Hirotaka Watada, Takashi Wada, Kohjiro Ueki, Ichiei Narita, Naoki Kashihara, Takashi Kadowaki, Hiroki Hase, Tadao Akizawa
Publikováno v: Nephrology Dialysis Transplantation. 38:1204-1216
Background Diabetic kidney disease (DKD) is the leading cause of end-stage kidney disease (ESKD), but currently available treatments do not improve kidney function or prevent the initiation of dialysis/kidney replacement therapy. A previous study dem
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d1255412f3f34a24add3d4660c6594
https://doi.org/10.1093/ndt/gfac242
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje