Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Masahiro, Asakage"'
Autor:
Hideyo Miyato, Masahiro Asakage, Daisuke Souma, Jun Yamada, Joji Kitayama, Hiroharu Yamashita, Hirokazu Nagawa
Publikováno v:
Journal of Surgical Research. 155:40-47
Orally applicable Δ9-tetrahydrocannabinol and its synthetic derivatives have been used as antiemetic drugs during chemotherapy in cancer patients. However, it is not well known how cannabinoids influence the effects of chemotherapeutic agents on mal
Autor:
Jun Yamada, Satomi Yoneyama, Hirokazu Nagawa, Takeshi Tsuchiya, Kazushige Kawai, Takuya Osada, Koki Takahashi, Eiji Sunami, Joji Kitayama, Yurai Okaji, Masahiro Asakage, Nelson H. Tsuno
Publikováno v:
Journal of Allergy and Clinical Immunology. 121:209-214
Background Epigallocatechin gallate (EGCG), a component of green tea catechin with the strongest biological activity, has been focused in recent years because of its anti-inflammatory and immunomodulatory activities. Dendritic cells (DCs) are profess
Autor:
Shin Fujii, Hiroharu Yamashita, Shoichi Kaizaki, Makoto Ishikawa, Hiroshi Nakayama, Hiroyuki Suzuki, Kenji Hatono, Joji Kitayama, Akihiro Sako, Tomomi Inoue, Hironori Ishigami, Masahiro Asakage, Hirokazu Nagawa
Publikováno v:
World Journal of Surgery. 29:1415-1420
To determine the clinical efficacy of Roux-en-Y reconstruction (RY) after distal gastrectomy, we compared postoperative outcomes of patients who underwent RY or conventional Billroth I reconstruction (B-I). A total of 50 patients were prospectively r
Autor:
Koki Takahashi, Takeshi Tsuchiya, Naoyuki Tsuchiya, Yurai Okaji, Shinsuke Saito, Joji Kitayama, Hirokazu Nagawa, Tsuyoshi Takahashi, Nelson H. Tsuno, Daisuke Sakurai, Kentaro Yazawa, Masahiro Asakage, Katsushi Tokunaga, Kazushige Kawai
Publikováno v:
Journal of Immunological Methods. 295:183-193
Analysis of specific properties of tumor endothelium should be useful for development of novel antiangiogenic strategies. However, the isolation of pure endothelial cells from tumor tissues is still a fundamental problem. In this study, we have attem
Autor:
Hirokazu Nagawa, Nobukazu Hori, Toshiaki Watanabe, Koki Takahashi, Masahiro Asakage, Nelson H. Tsuno, Yurai Okaji, Kazushige Kawai, Joji Kitayama, Kentaro Yazawa
Publikováno v:
Journal of Allergy and Clinical Immunology. 113:1211-1217
Background Although green tea polyphenol catechin has been reported to have antiallergic and anti-inflammatory activities, the precise mechanisms of its effect on the immune system have been poorly investigated. Objective In this study, we aimed to e
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 39(7)
The patient was a 72-year-old woman, admitted to our hospital due to appetite loss. We performed gastroscopy, colonoscopy and abdominal CT. She had both advanced ascending colon cancer with multiple liver metastasis(cStage IV: cT3N1H3)and early gastr
Autor:
Takeshi, Tsuchiya, Nelson H, Tsuno, Masahiro, Asakage, Jun, Yamada, Satomi, Yoneyama, Yurai, Okaji, Shin, Sasaki, Joji, Kitayama, Takuya, Osada, Koki, Takahashi, Hirokazu, Nagawa
Publikováno v:
Hepato-gastroenterology. 55(84)
The p38 mitogen-activated protein kinases (p38 MAPKs) function in a wide variety of signaling pathways. However, the role of p38s is cell type- and stimulus-dependent. The present study aimed to evaluate the effects of p38 MAPK inhibitor on human col
Autor:
Satomi Yoneyama, Takeshi Tsuchiya, Joji Kitayama, Takeshi Nishikawa, Junichiro Tanaka, Jun Yamada, Yurai Okaji, Nelson H. Tsuno, Masahiro Asakage, Yasutaka Shuno, Koki Takahashi, Hirokazu Nagawa
Publikováno v:
The Journal of surgical research. 151(1)
Background Zoledronic acid (ZOL) is clinically available for the treatment of skeletal complications. In preclinical studies, strong anti-cancer activities against breast cancer, prostate cancer, and leukemia were reported. It also inhibited the prol
Autor:
Hirokazu Nagawa, Jun Yamada, Koki Takahashi, Kazushige Kawai, Nelson H. Tsuno, Masahiro Asakage, Takeshi Tsuchiya, Joji Kitayama, Yurai Okaji, Satomi Yoneyama
Publikováno v:
Planta medica. 73(10)
Although some isoprenoids, such as taxans and geranylgeraniol (GGOH), have been reported to have strong anticancer activities, the effect of plaunotol, the isoprenoid extracted from the leaves of Plau-noi, on cancer has not yet been evaluated. Here,
Sulforaphane induces inhibition of human umbilical vein endothelial cells proliferation by apoptosis
Autor:
Takeshi Tsuchiya, Hirokazu Nagawa, Shoichi Kaisaki, Jun Yamada, Satomi Yoneyama, Takuya Osada, Koki Takahashi, Yurai Okaji, Joji Kitayama, Nelson H. Tsuno, Masahiro Asakage
Publikováno v:
Angiogenesis. 9(2)
Sulforaphane (SUL), one of the isothiocyanates (ITCs), has recently been focused due to its inhibitory effects on tumor cell growth in vitro and in vivo, which is dependent on the direct effect on cancer cells. In the present study, we aimed to inves