Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Masahiko YASUDA"'
Autor:
Peter Gee, Mandy S. Y. Lung, Yuya Okuzaki, Noriko Sasakawa, Takahiro Iguchi, Yukimasa Makita, Hiroyuki Hozumi, Yasutomo Miura, Lucy F. Yang, Mio Iwasaki, Xiou H. Wang, Matthew A. Waller, Nanako Shirai, Yasuko O. Abe, Yoko Fujita, Kei Watanabe, Akihiro Kagita, Kumiko A. Iwabuchi, Masahiko Yasuda, Huaigeng Xu, Takeshi Noda, Jun Komano, Hidetoshi Sakurai, Naoto Inukai, Akitsu Hotta
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Expression of Cas9 and gRNA from viral vectors in vivo may cause off-target activity. Here the authors present NanoMEDIC, which uses nanovesicles to transiently deliver editing machinery to hard-to-transfect cells.
Externí odkaz:
https://doaj.org/article/4d0fe2ef9a604f0fb6865d1e08b1ed50
Autor:
Nobuhito Hayashimoto, Takashi Inoue, Hanako Morita, Masahiko Yasuda, Masami Ueno, Kenji Kawai, Toshio Itoh
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160116 (2016)
Common marmosets (Callithrix jacchus) are frequently used for biomedical research but can be afflicted with diarrhea-a serious and potentially lethal health problem. Enteropathogenic Escherichia coli (EPEC) is thought to be the causative pathogen of
Externí odkaz:
https://doaj.org/article/ba719d0f04ec4d1baaa6b3044e6b4348
Autor:
Nobuhito Hayashimoto, Hanako Morita, Yamamoto Masafumi, Masahiko Yasuda, Yuyo Ka, Yurina Tomiyama, Tomoyuki Ogura, Ritsuki Uchida, Kenji Kawai, Hiroshi Suemizu
Publikováno v:
Experimental Animals
Astroviruses are often associated with gastrointestinal diseases in mammals and birds. Murine astrovirus (MuAstV) is frequently detected in laboratory mice. Previous studies on MuAstV in mice did not report any symptoms or lesions. However, little in
Autor:
Nobuhito Hayashimoto, Hanako Morita, Masahiko Yasuda, Mai Tanaka, Ritsuki Uchida, Tomoko Ishida, Yamamoto Masafumi
Publikováno v:
The Journal of Veterinary Medical Science
To investigate the prevalence of murine astrovirus (MuAstV) in mice in laboratory animal facilities in Japan, a polymerase chain reaction (PCR) test targeting the RNA-dependent RNA polymerase (RdRP) gene was performed on the cecum contents of 1,212 m
Autor:
Masahiko, Yasuda, Ritsuki, Uchida, Yoko, Kamai, Hanako, Morita, Mai, Tanaka, Tomoko, Ishida, Misa, Mochizuki, Masafumi, Yamamoto, Nobuhito, Hayashimoto, Kenji, Kawai
Publikováno v:
Experimental animals. 71(1)
Pneumocystis (P.) carinii is known to cause fatal pneumonia in immunocompromised rats. Cases of P. carinii interstitial pneumonia in immunocompetent rats have been shown histologically to present with perivascular lymphoid cuffs, which have previousl
Autor:
Takuma Mizusawa, Hidetoshi Sakurai, Mingming Zhao, Mitsuru Sasaki-Honda, Akitsu Hotta, Tatsuya Jonouchi, Antonio Lucena-Cacace, Masahiko Yasuda, Minas Nalbandian, Yoshinori Yoshida
Publikováno v:
Stem Cell Reports
Summary The transplantation of muscle progenitor cells (MuPCs) differentiated from human induced pluripotent stem cells (hiPSCs) is a promising approach for treating skeletal muscle diseases such as Duchenne muscular dystrophy (DMD). However, proper
Autor:
Erika Sasaki, Terumi Yurimoto, Takayuki Mineshige, Kenji Kawai, Masahiko Yasuda, Takashi Inoue
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Common marmosets (Callithrix jacchus) are frequently used for biomedical research but gastrointestinal diseases have been major health problems to maintain captive marmosets. We have diagnosed a novel gastrointestinal disease in marmosets, as which w
Autor:
Kumiko Iwabuchi, Akihiro Kagita, Lucy F. Yang, Nanako Shirai, Takahiro Iguchi, Yoko Fujita, Jun Komano, Takeshi Noda, Akitsu Hotta, Noriko Sasakawa, Yukimasa Makita, Matthew A. Waller, Naoto Inukai, Peter Gee, Mio Iwasaki, Mandy S. Y. Lung, Hidetoshi Sakurai, Yasuko O. Abe, Xiou H. Wang, Yasutomo Miura, Kei Watanabe, Masahiko Yasuda, Hiroyuki Hozumi, Huaigeng Xu, Yuya Okuzaki
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Nature Communications
Prolonged expression of the CRISPR-Cas9 nuclease and gRNA from viral vectors may cause off-target mutagenesis and immunogenicity. Thus, a transient delivery system is needed for therapeutic genome editing applications. Here, we develop an extracellul
Publikováno v:
Experimental Animals. 67:487-492
Strong evidence for an association between idiopathic thrombocytopenic purpura (ITP) and Helicobacter pylori (HP) infection has been reported in humans. Chronic ITP is known to be improved by the eradication of HP. The purpose of this study was to re
Autor:
Takayuki Goto, Nobuhito Hayashimoto, Yukito Kiyokawa, Masahiko Yasuda, Hideki Shinohara, Kenji Kawai, Tomoyuki Ogura, Chie Shimomura, Yoko Kamai, Mika Yagoto, Riichi Takahashi
Publikováno v:
Experimental Animals. 66:425-435
Severely immunodeficient NOD/Shi-scid, IL-2Rγnull (NOG) mice provide an in vivo model for human cell/tissue transplantation studies. NOG mice were established by combining interleukin-2 receptor-γ chain knockout mice and NOD/Shi-scid mice. They exh