Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Masahiko Soga"'
Autor:
Masahiko Soga, Takaya Izumi, Isamu Nanchi, Narumi Horita, Miyuki Yamamoto, Shiori Kawasaki, Koichi Ogawa, Masahide Fujita, Yasuhide Morioka
Publikováno v:
PAIN Reports, Vol 6, Iss 3, p e951 (2021)
Abstract. Introduction:. Transient receptor potential vanilloid 4 (TRPV4) modulates osteoarthritic (OA) pain in animal models. However, the pathophysiological function of TRPV4 in regulating OA pain remains poorly understood. Methods:. We developed T
Externí odkaz:
https://doaj.org/article/766c588121364c85aee24badfea421d5
Autor:
Masahiko, Soga
Publikováno v:
岡山理科大学紀要. B, 人文・社会科学. 55:83-99
Autor:
Narumi Horita, Shiori Kawasaki, Masahiko Soga, Koichi Ogawa, Masahide Fujita, Takaya Izumi, Isamu Nanchi, Miyuki Yamamoto, Yasuhide Morioka
Publikováno v:
Pain Reports
PAIN Reports, Vol 6, Iss 3, p e951 (2021)
PAIN Reports, Vol 6, Iss 3, p e951 (2021)
Supplemental Digital Content is Available in the Text. Knee joint pain in osteoarthritis model rats is caused by the sensitization of transient receptor potential vanilloid 4 in the dorsal root ganglion neurons
Introduction: Transient receptor p
Introduction: Transient receptor p
Autor:
Narumi Horita, Daiki Nagamatsu, Yasuhide Morioka, Miki Tanimura, Gaku Sakaguchi, Azusa Nozu, Yasuyoshi Iso, Toshiyuki Kanemasa, Natsue Yamanada, Mikie Hinata, Toshiyuki Asaki, Masayuki Imai, Hidetoshi Matsuda, Kenji Takaya, Osamu Yoshida, Hiromi Nakai, Akira Yukimasa, Shinji Suzuki, Masahiko Soga, Naoki Tsuno, Tomoyuki Ogawa, Hiroki Yamaguchi, Miyuki Yamamoto, Satoko Funaki, Motohiro Fujiu
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:2177-2190
A novel series of (6-aminopyridin-3-yl)(4-(pyridin-2-yl)piperazin-1-yl) methanone derivatives were identified as selective transient receptor potential vanilloid 4 (TRPV4) channel antagonist and showed analgesic effect in Freund's Complete Adjuvant (
Autor:
Akira Oita, Josué A. Velázquez-Moyado, Mohamed Habib Grissa, Zhi Dong, Nizar Fredj, Adel Sekma, Adelfo Reyes-Ramírez, Takayo Haruna, Kaoru Ogawa, Tin Sandar Zaw, Hiiragi Sugo, Semir Nouira, Wen-Bin Wu, Katsuaki Dan, Hiroshi Sakonjo, Juan Carlos Castillo-Hernández, Martín González-Andrade, Mi Tang, Kinichi Imura, Tomio Okamura, Jun Hayakawa, Masashi Deguchi, Yuka Terada, Menglin Rao, Kamel Monastiri, Haruka Saeki, Uy Dong Sohn, Takashi Shimosato, Hideki Hasegawa, Akinori Arimura, Yasuhide Morioka, Chi Zhang, Mitsutaka Takada, Elena G. Ramírez-López, Emna Kerkeni, Malek Mzali, Kohei Wakitani, Kyoichi Wada, Saki Hiruma, Yuichi Uwai, Tsong-Long Hwang, Takaya Miyazaki, Yujie Cheng, Jihua Ma, Fumiko Sekiguchi, Phyu Phyu Khin, Keita Takanashi, Nejia Tounsi, Sho Kanzaki, Huey-Ming Lo, Masashi Matsumoto, Jie Hao, Junlian Xing, Wanzhen Jiang, Druckerei Stückle, Masashi Tawa, Yoshinori Funakami, Wahiba Douki, Kenji Watanabe, Zhipei Liu, Maho Tsubota, Yoko Furue, Tomoyoshi Miyamoto, Imen Trabelsi, Atsufumi Kawabata, Mina Yamamoto, Kiyoshi Yasui, Sha Liu, Ilhem Hellara, Andrés Navarrete, Peihua Zhang, Xinrong Fan, Masahiko Soga, Antao Luo, Tomohiro Nabekura, Tatsuya Kawasaki
Publikováno v:
Pharmacology. 99:I-IV
Autor:
Sunao Imai, Isamu Nanchi, Naoki Tsuno, Yusuke Sakurai, Yasuhide Morioka, Miyuki Yamamoto, Shiori Kawasaki, Masahide Fujita, Masahiko Soga, Toshiyuki Asaki, Tatsuya Takahashi
Publikováno v:
European Journal of Pharmacology. 899:174040
Transient receptor potential vanilloid 4 (TRPV4) is a non-selective cation channel activated by various physical stimuli such as cell swelling and shear stress. TRPV4 is expressed in bladder sensory nerves and epithelium, and its activation produces
Autor:
Gaku Sakaguchi, Tetsuji Ito, Naoki Tsuno, Mikie Hinata, Akira Yukimasa, Yasuyoshi Iso, Satoko Funaki, Daiki Nagamatsu, Miki Tanimura, Miyuki Yamamoto, Tatsuhiko Ueno, Toshiyuki Kanemasa, Yoko Nishimura, Masahiko Soga, Natsue Yamanada, Yasuhide Morioka, Osamu Yoshida, Narumi Horita, Masayuki Imai, Takatsugu Inoue, Yusuke Ichihashi, Hiroki Yamaguchi, Hidetoshi Matsuda
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:4930-4935
A novel series of 2',4'-dimethyl-[4,5'-bithiazol]-2-yl amino derivatives were found by high throughput screening of the TRPV4 receptor, at which these compounds showed competitive antagonist potential against 4α-phorbol 12,13-didecanoate (4αPDD) as
Autor:
Masabumi Minami, Masayuki Imai, Minoru Hasegawa, Gaku Sakaguchi, Takeshi Yoshioka, Narumi Horita, Atsushi Morita, Junji Tsuchida, Yasuhide Morioka, Mikie Hinata, Kenichi Higashino, Shoji Yamane, Isao Fukuda, Masahiko Soga, Takao Sanaki, Minoru Ikeda, Toshiyuki Kanemasa, Miyuki Yamamoto, Sunao Imai
Publikováno v:
Pain. 159(5)
Transient receptor potential vanilloid 4 (TRPV4) receptor modulates pain, and this has been noted in several animal models. However, the involvement of TRPV4 in osteoarthritic (OA) pain remains poorly understood. This study assessed the functional ch
Autor:
Kinichi Imura, Takayo Haruna, Akinori Arimura, Kiyoshi Yasui, Mina Yamamoto, Masashi Deguchi, Yasuhide Morioka, Jun Hayakawa, Masahiko Soga, Yoko Furue
Publikováno v:
Pharmacology. 99(5-6)
We investigated the effects of S-777469 (1-[[6-Ethyl-1-[4-fluorobenzyl]-5-methyl-2-oxo-1, 2-dihydropyridine-3-carbonyl]amino]-cyclohexanecarboxylic acid), a novel cannabinoid type 2 receptor (CB2) agonist, on 1-fluoro-2,4-dinitrobenzene (DNFB)-induce