Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Masahiko Okuma"'
Autor:
Koji Akeda, E. J-M. A. Thonar, Kei Miyamoto, Masahiko Okuma, Robert L. Sah, Howard S. An, Koichi Masuda, Mohamed Attawia, Mary Ellen Lenz
Publikováno v:
Osteoarthritis and Cartilage. 14:1272-1280
SummaryObjectivePlatelet-rich plasma (PRP) is a fraction of plasma that contains high levels of multiple growth factors. The purpose of this study was to examine the effects of PRP on cell proliferation and matrix synthesis by porcine chondrocytes cu
Publikováno v:
Spine. 31:E91-E97
STUDY DESIGN An in vivo study on the effects of an agent for scar prevention in a dog laminectomy model. OBJECTIVE To examine the anti-adhesion properties of a thrombin-based hemostatic gelatin (FLOSEAL; Baxter International Inc., Deerfield, IL). SUM
Autor:
Eugene J.-M.A. Thonar, Kei Miyamoto, Howard S. An, Koichi Masuda, Robert L. Sah, Koji Akeda, Masahiko Okuma, Lori Otten
Publikováno v:
Spine. 30:2398-2405
STUDY DESIGN In vitro study on the effects of pulsed low intensity ultrasound on the cellular metabolism of bovine intervertebral disc cells. OBJECTIVE To determine whether pulsed low intensity ultrasound has effects on cell proliferation and extrace
Autor:
Tomoko Nakai, Daisuke Sakai, Masahiko Okuma, Tomomitsu Hotta, Yukihiro Yamamoto, Joji Mochida, Kiyoshi Ando, Takeshi Nomura, Kazuhiro Nishimura
Publikováno v:
Biomaterials. 24:3531-3541
Intervertebral disc degeneration is considered to be one of the major causes of low back pain. Despite this irreversible phenomenon, attempts to decelerate disc degeneration using various techniques have been reported. However, to date there has been
Publikováno v:
Connective Tissue Research. 44:104-108
We examined the emergence and sequential changes in type I, II, and VI collagen production in an experimental rabbit model of disc degeneration. Type I collagen was minimally present initially and did not change over 24 weeks. Type I collagen seemed
Publikováno v:
Clinical Orthopaedics and Related Research. 389:94-101
Autogenous implantation of nucleus pulposus or nucleus pulposus cells that were activated by coculture retards intervertebral disc degeneration, but harvesting such grafts causes disc degeneration at the donor site. This study examined whether nucleu
Autor:
Hiroyuki Aikawa, Mariko Onoe, Takaaki Kinoue, Kou Sakabe, Takahiko Yoshida, Fujio Kayama, Masahiko Okuma
Publikováno v:
Pathophysiology. 6:231-236
SS-A/Ro autoantibodies are detected at high levels in patients with autoimmune diseases such as Sjogren’s syndrome. It has been reported that natural oestrogen is capable of inducing cell surface expression of SS-A/Ro autoantigens in salivary gland
Autor:
Fujio Kayama, Masahiko Okuma, Wataru Fujii, Hiroyuki Furuya, Michitake Kazuno, Yoshihide Suwa, Kou Sakabe, Toshiya Yamaguchi, Takahiko Yoshida, Kerin L Fresa
Publikováno v:
International Journal of Immunopharmacology. 20:205-212
The present study was an attempt to elucidate the effect of estrogenic xenobiotics on the proliferation of mitogen-stimulated human peripheral blood lymphocyte (PBL). Our findings follow : (a) the proliferation of PBL in response to phytohemagglutini
Publikováno v:
Pathophysiology. 5:73-77
The present study was an attempt to elucidate the effect of sex steroids (estradiol-17 β and 5 α -dihydrotestosterone) on the mitogen-stimulated human peripheral blood lymphocytes (PBL) proliferation. Our findings were as follows: (a) the prolifera
Publikováno v:
Pathophysiology. 4:281-288
The mechanism of action of sex steroid hormones (SHs), androgen (A) or oestrogen (E), on the protein kinase C (PKC)-related signal transduction pathway was examined in culture of a rat thymus epithelial cell line (TEC; IT-45R1). The results were as f