Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Masahiko Okiyama"'
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 120(2)
An active metabolite, ddATP, of didanosine that is an analogue of purine-nucleoside (a component of nucleic acid) was known to inhibit the activity of DNA polymerase for E. coli. In 1985, Dr. Michiya et al. of NCI reported that didanosine and ddA inh
Autor:
Yoshinobu Toshimitsu, Makoto Nishimura, Mariko Maeda, Mayumi Simizu, Mayumi Yamada, Hajime Fujiwara, Mariko Kudo, Masahiko Okiyama
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 98(1)
The bronchodilating effect and other related pharmacological properties of SN-408 were studied in comparison with those of isoproterenol, salbutamol and procaterol. SN-408 caused concentration-dependent relaxation of isolated guinea pig trachea via t
Publikováno v:
Japanese Journal of Pharmacology. 55:363
Autor:
Yoshifumi Gotoh, Masahiko Okiyama, Yoshinobu Toshimitsu, Makoto Nishimura, Nami Nakano, Rieko Hiroumi
Publikováno v:
Japanese Journal of Pharmacology. 55:363
Autor:
Rieko Hiroumi, Masahiko Okiyama, Yoshifumi Gotoh, Makoto Nishimura, Nami Nakano, Yoshinobu Toshimitsu
Publikováno v:
Japanese Journal of Pharmacology. 55:363
Publikováno v:
Japanese Journal of Pharmacology. 52:307
Autor:
Akio Ebihara, Kunihisa Manbo, Masahiko Okiyama, Takeshi Watabe, Kazuji Tawara, Kyoichi Ohashi, Taichi Oka, Kazuoki Kondo
Publikováno v:
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 13:265-271
Publikováno v:
Journal of Pharmaceutical Sciences. 76:880-885
This report describes observations of the relationship between the pharmacokinetics and pharmacodynamics of diazepam (7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one ; 5 mg/kg) during the concomitant administration of diazepam and i
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 90(3)
In this report, we studied drug interaction between oxazepam and imipramine in rats. Oxazepam (20 mg/kg) and imipramine (20 or 50 mg/kg) were administrated orally. The oxazepam concentration in plasma, brain and liver were measured by the method of H
Publikováno v:
Journal of pharmaceutical sciences. 77(1)
The concomitant administration of diazepam and imipramine hydrochloride increased desipramine concentration in rat plasma, but decreased 2-hydroxyimipramine and 2-hydroxydesipramine concentrations; the concomitant administration of oxazepam and imipr