Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Masahiko Makino"'
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004881 (2016)
Mycobacterium leprae is the causative agent of leprosy and also known to possess unique features such as inability to proliferate in vitro. Among the cellular components of M. leprae, various glycolipids present on the cell envelope are well characte
Externí odkaz:
https://doaj.org/article/f15fcd391cdf4a99a4709f4bcb035398
Autor:
Tsuyoshi Sekizuka, Masanori Kai, Kazue Nakanaga, Noboru Nakata, Yuko Kazumi, Shinji Maeda, Masahiko Makino, Yoshihiko Hoshino, Makoto Kuroda
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114848 (2014)
Mycobacterium abscessus group subsp., such as M. massiliense, M. abscessus sensu stricto and M. bolletii, are an environmental organism found in soil, water and other ecological niches, and have been isolated from respiratory tract infection, skin an
Externí odkaz:
https://doaj.org/article/1a955cc94dbb4c82b6c2cfe35e7edb18
Autor:
Yang Degang, Takeshi Akama, Takeshi Hara, Kazunari Tanigawa, Yuko Ishido, Masaichi Gidoh, Masahiko Makino, Norihisa Ishii, Koichi Suzuki
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 12, p e1936 (2012)
Mycobacterium leprae (M. leprae) lives and replicates within macrophages in a foamy, lipid-laden phagosome. The lipids provide essential nutrition for the mycobacteria, and M. leprae infection modulates expression of important host proteins related t
Externí odkaz:
https://doaj.org/article/b4f3c388834e458ea0f5c9c212710a8a
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 11, p e1401 (2011)
Little is known of the direct microbicidal activity of T cells in leprosy, so a lipopeptide consisting of the N-terminal 13 amino acids lipopeptide (LipoK) of a 33-kD lipoprotein of Mycobacterium leprae, was synthesized. LipoK activated M. leprae inf
Externí odkaz:
https://doaj.org/article/54b80051cdb74e6db95a50dfcc07424d
Autor:
Shunsuke Kudo, Ayumu Miyakawa, Tatsuji Sugimori, Yoshiharu Otsuka, makoto yanagida, Masahiko Makino, Toshinori Sasaki, Shigeo Okuma, Tadashi Nakatsuka
Publikováno v:
ASEG Extended Abstracts. 2018:1-4
The Ohi nuclear power station is located at the northern Oshima Peninsula in the Wakasa Bay on the coast of Japan Sea, central Japan. The geology of the site of the power station is composed mainly of shales, diabases, gabbros and ultramafic rocks of
Autor:
Tetsu Mukai, Manabu Ato, Masahiko Makino, Yuji Miyamoto, Yumiko Tsukamoto, Yumi Maeda, Toshiki Tamura
Publikováno v:
Tuberculosis. 129:102105
Mycobacterium bovis BCG has been the only practical vaccine for tuberculosis. However, BCG cannot fully prevent adult pulmonary tuberculosis. Therefore, the improvement of BCG vaccine is necessary. We previously produced recombinant (r) BCG (BCG-PEST
Autor:
Saburo Yamamoto, Yumi Maeda, Yumiko Tsukamoto, Satoshi Mitarai, Tetsu Mukai, Masahiko Makino, Toshiki Tamura
Publikováno v:
Vaccine. 34:6301-6308
Enhancement of the T cell-stimulating ability of Mycobacterium bovis BCG (BCG) is necessary to develop an effective tuberculosis vaccine. For this purpose, we introduced the PEST-HSP70-major membrane protein-II (MMPII)-PEST fusion gene into ureC-gene
Autor:
Yumi Maeda, Masahiko Makino, Meiwen Yu, Weijing Liu, Toshiki Tamura, Hong-sheng Wang, Yali Jin, Haiqin Jiang
Publikováno v:
Diagnostic Microbiology and Infectious Disease. 83:274-277
Antibodies to phenolic glycolipid (PGL)-I and major membrane protein (MMP)-II were evaluated for serodiagnosis of leprosy in Southwest China, and the role in predicting the occurrence of the disease in household contacts (HHCs) of leprosy was examine
Publikováno v:
Volume 2: Development and Applications in Computational Fluid Dynamics; Industrial and Environmental Applications of Fluid Mechanics; Fluid Measurement and Instrumentation; Cavitation and Phase Change.
The turbulent structure of flow field with microbubbles which is generated by electrolysis in a horizontal water channel is investigated at Reynolds number Rem = 24000 (based on the channel height). Firstly, Shadow Image Technique (SIT) is applied to
Autor:
Masahiko Makino, Maria T. Pena, Yumi Maeda, Michael Polydefkis, Steven G. Reed, Rahul Sharma, Kelly Cunningham, Thomas P. Gillis, Malcolm S. Duthie, Gigi J. Ebenezer, Richard W. Truman
Publikováno v:
npj Vaccines, Vol 3, Iss 1, Pp 1-1 (2018)
NPJ Vaccines
NPJ Vaccines
Sustained elimination of leprosy as a global health concern likely requires a vaccine. The current standard, BCG, confers only partial protection and precipitates paucibacillary (PB) disease in some instances. When injected into mice with the T helpe