Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Masahiko Kume"'
Autor:
Hirohito Abo, Masahiko Kume, Federico Pecori, Taichi Miura, Naoki Matsumoto, Shoko Nishihara, Kazuo Yamamoto
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0267804 (2022)
O-GlcNAcylation is the only sugar modification for proteins present in the cytoplasm and nucleus and is thought to be involved in the regulation of protein function and localization. Currently, several methods are known for detecting O-GlcNAcylated p
Externí odkaz:
https://doaj.org/article/21f1c918c7484818bb887fdb1c5f04b3
Autor:
Federico Pecori, Nanako Kondo, Chika Ogura, Taichi Miura, Masahiko Kume, Youhei Minamijima, Kazuo Yamamoto, Shoko Nishihara
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109361- (2021)
Summary: Mouse embryonic stem cell (ESC) pluripotency is tightly regulated by a complex network composed of extrinsic and intrinsic factors that allow proper organismal development. O-linked β-N-acetylglucosamine (O-GlcNAc) is the sole glycosylation
Externí odkaz:
https://doaj.org/article/951224586e5242feb28111d701e109ec
Autor:
Hirohisa Chiyoda, Masahiko Kume, Carla Cadena Del Castillo, Kenji Kontani, Anne Spang, Toshiaki Katada, Masamitsu Fukuyama
Publikováno v:
PLoS Genetics, Vol 17, Iss 4, p e1009457 (2021)
Spatiotemporal restriction of signaling plays a critical role in animal development and tissue homeostasis. All stem and progenitor cells in newly hatched C. elegans larvae are quiescent and capable of suspending their development until sufficient fo
Externí odkaz:
https://doaj.org/article/b0a9882bbb8243e784ddc8c6ac1a01e3
Autor:
Taichi Miura, Masahiko Kume, Takeshi Kawamura, Kazuo Yamamoto, Takao Hamakubo, Shoko Nishihara
Publikováno v:
Stem Cell Reports, Vol 10, Iss 1, Pp 272-286 (2018)
Summary: Mouse embryonic stem cells (ESCs) differentiate into multiple cell types during organismal development. Fibroblast growth factor 4 (FGF4) signaling induces differentiation from ESCs via the phosphorylation of downstream molecules such as mit
Externí odkaz:
https://doaj.org/article/c0cd61de082b4e72af90d2b34493aa99
Autor:
Fumiyoshi Okano, Takanori Saito, Yoshitaka Minamida, Shinichi Kobayashi, Takayoshi Ido, Yasushi Miyauchi, Ukei Wasai, Daisuke Akazawa, Masahiko Kume, Masaki Ishibashi, Ke Jiang, Alexandra Aicher, Christopher Heeschen, Tetsu Yonehara
Publikováno v:
Cancer Research Communications. 3:640-658
Specific targets for cancer treatment are highly desirable, but still remain to be discovered. While previous reports suggested that CAPRIN-1 localizes in the cytoplasm, here we now show that part of this molecule is strongly expressed on the cell me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cb0bd7fc9d4e63ad33501ff6a7a75d5
https://doi.org/10.1158/2767-9764.crc-22-0310
https://doi.org/10.1158/2767-9764.crc-22-0310
Autor:
Tetsu Yonehara, Christopher Heeschen, Alexandra Aicher, Ke Jiang, Masaki Ishibashi, Masahiko Kume, Daisuke Akazawa, Ukei Wasai, Yasushi Miyauchi, Takayoshi Ido, Shinichi Kobayashi, Yoshitaka Minamida, Takanori Saito, Fumiyoshi Okano
CAPRIN-1 correlated to the cell proliferation and viability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cbf7da1a367f930da58125789ee6235
https://doi.org/10.1158/2767-9764.22651606.v1
https://doi.org/10.1158/2767-9764.22651606.v1
Autor:
Tetsu Yonehara, Christopher Heeschen, Alexandra Aicher, Ke Jiang, Masaki Ishibashi, Masahiko Kume, Daisuke Akazawa, Ukei Wasai, Yasushi Miyauchi, Takayoshi Ido, Shinichi Kobayashi, Yoshitaka Minamida, Takanori Saito, Fumiyoshi Okano
Clinical, pathological findings in the toxicity study in Cynomolgus Monkeys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c077004e599d882ef3948cbbdd5fc87
https://doi.org/10.1158/2767-9764.22651579
https://doi.org/10.1158/2767-9764.22651579
Autor:
Tetsu Yonehara, Christopher Heeschen, Alexandra Aicher, Ke Jiang, Masaki Ishibashi, Masahiko Kume, Daisuke Akazawa, Ukei Wasai, Yasushi Miyauchi, Takayoshi Ido, Shinichi Kobayashi, Yoshitaka Minamida, Takanori Saito, Fumiyoshi Okano
Specific targets for cancer treatment are highly desirable, but still remain to be discovered. While previous reports suggested that CAPRIN-1 localizes in the cytoplasm, here we now show that part of this molecule is strongly expressed on the cell me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7980d50cbf4abd9e6e06cb85e6cc54
https://doi.org/10.1158/2767-9764.c.6604891.v1
https://doi.org/10.1158/2767-9764.c.6604891.v1
Autor:
Satoshi Kawano, Yusuke Adachi, Megumi Kuronishi, Kohta Toshimitsu, Kotaro Kodama, Takayuki Kimura, Masahiko Kume, Jialing Shen, Saori Watanabe Miyano, Akira Yokoi, Junji Matsui, Yu Kato, Yasuhiro Funahashi
Publikováno v:
Cancer Research. 83:1830-1830
Introduction: Combination anti-CTLA-4 antibody (Ab) + anti-PD-1 Ab is approved in multiple cancer types and has improved clinical outcomes. In addition, atezolizumab + bevacizumab combination therapy is approved for unresectable hepatocellular carcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7539609700036977ed43ec364713cdf
https://doi.org/10.1158/1538-7445.am2023-1830
https://doi.org/10.1158/1538-7445.am2023-1830
Publikováno v:
Biochemical and Biophysical Research Communications. 520:532-537
The animal body contains various types of stem and progenitor cells. These undifferentiated cells coordinate the balance between quiescence and proliferation with dynamics of various physiological conditions such as the developmental stage, food avai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abca03c42d3ec0c46f72131e950bc398
https://doi.org/10.1016/j.bbrc.2019.10.045
https://doi.org/10.1016/j.bbrc.2019.10.045