Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Masahiko Hoshijima"'
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-5 (2021)
Abstract Background Exotoxins secreted from Staphylococcus aureus or Streptococcus pyogenes act as superantigens that induce systemic release of inflammatory cytokines and are a common cause of toxic shock syndrome (TSS). However, little is known abo
Externí odkaz:
https://doaj.org/article/b8ed4cbab80547bfacaf1d834d052391
Autor:
Vijay Rajagopal, Gregory Bass, Cameron G Walker, David J Crossman, Amorita Petzer, Anthony Hickey, Ivo Siekmann, Masahiko Hoshijima, Mark H Ellisman, Edmund J Crampin, Christian Soeller
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 9, p e1004417 (2015)
Spatio-temporal dynamics of intracellular calcium, [Ca2+]i, regulate the contractile function of cardiac muscle cells. Measuring [Ca2+]i flux is central to the study of mechanisms that underlie both normal cardiac function and calcium-dependent etiol
Externí odkaz:
https://doaj.org/article/ef0aa2a9574e4d2a936460542810080d
Autor:
Takanobu Nagata, Hideo Yasukawa, Sachiko Kyogoku, Toyoharu Oba, Jinya Takahashi, Shoichiro Nohara, Tomoko Minami, Kazutoshi Mawatari, Yusuke Sugi, Koutatsu Shimozono, Sylvain Pradervand, Masahiko Hoshijima, Hiroki Aoki, Yoshihiro Fukumoto, Tsutomu Imaizumi
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127942 (2015)
Myocardial ischemia reperfusion injury (IRI) adversely affects cardiac performance and the prognosis of patients with acute myocardial infarction. Although myocardial signal transducer and activator of transcription (STAT) 3 is potently cardioprotect
Externí odkaz:
https://doaj.org/article/8d05709fc4874091845e44d11e40e62e
Autor:
Yosuke Miyazaki, Yasuhiro Ikeda, Kozo Shiraishi, Shizuka N Fujimoto, Hidekazu Aoyama, Koichi Yoshimura, Makoto Inui, Masahiko Hoshijima, Hideko Kasahara, Hiroki Aoki, Masunori Matsuzaki
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35875 (2012)
BACKGROUND: The targeting of Ca(2+) cycling has emerged as a potential therapy for the treatment of severe heart failure. These approaches include gene therapy directed at overexpressing sarcoplasmic reticulum (SR) Ca(2+) ATPase, or ablation of phosp
Externí odkaz:
https://doaj.org/article/5d4fc8c1382344c8a6c56c7787b2d20e
Autor:
Yuhui Cheng, Zeyun Yu, Masahiko Hoshijima, Michael J Holst, Andrew D McCulloch, J Andrew McCammon, Anushka P Michailova
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 10, p e1000972 (2010)
The t-tubules of mammalian ventricular myocytes are invaginations of the cell membrane that occur at each Z-line. These invaginations branch within the cell to form a complex network that allows rapid propagation of the electrical signal, and hence s
Externí odkaz:
https://doaj.org/article/b247c9bc249a457594ed072a856a932b
Publikováno v:
World Journal of Clinical Cases
BACKGROUND High-flow nasal cannula (HFNC) therapy and morphine continuous subcutaneous infusion (CSI) have been used to ameliorate dyspnea in non-cancer patients with end-stage respiratory diseases, including chronic obstructive pulmonary disease and
Autor:
Takeshi Hatani, Shunsuke Funakoshi, Yoshinori Yoshida, Thomas J. Deerinck, Masahiko Hoshijima, Eric A. Bushong, Mark H. Ellisman, Hiroshi Takeshima, Takeshi Kimura
Publikováno v:
Biochem Biophys Res Commun
Many studies have shown the feasibility of in vivo cardiac transplantation of human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) in animal experiments. However, nano-structural confirmation of the successful incorporation of the en
Publikováno v:
BMC Infectious Diseases
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-5 (2021)
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-5 (2021)
Background Exotoxins secreted from Staphylococcus aureus or Streptococcus pyogenes act as superantigens that induce systemic release of inflammatory cytokines and are a common cause of toxic shock syndrome (TSS). However, little is known about TSS ca
Autor:
Hiroaki Tanaka, Makoto Someya, Andrew D. McCulloch, Masahiko Hoshijima, Satoshi Izumi, Asuka Hatano
Publikováno v:
IFMBE Proceedings ISBN: 9783030661687
How ultrastructural alterations in cardiomyocytes lead to heart disease remains unclear. Therefore, there is interest in simulate cardiac myocytes with realistic 3-D models of myocyte shape and structure. Using deep learning and image processing, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97767239e634d4de179171abc5e3c82a
https://doi.org/10.1007/978-3-030-66169-4_8
https://doi.org/10.1007/978-3-030-66169-4_8
Autor:
Mark H. Ellisman, Masahiko Hoshijima, Andrew D. McCulloch, Asuka Hatano, Makoto Someya, Satoshi Izumi, Hiroki Sakakima, Hiroaki Tanaka
Publikováno v:
Journal of Structural Biology. 214:107806
Mitochondrial morphological defects are a common feature of diseased cardiac myocytes. However, quantitative assessment of mitochondrial morphology is limited by the time-consuming manual segmentation of electron micrograph (EM) images. To advance un