Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Masahiko Hagihara"'
Autor:
Tomonoshin Kanazawa, Keisuke Ohta, Masahiko Hagihara, Shingo Hirashima, Motohisa Shimizu, Kei-ichiro Nakamura
Publikováno v:
Journal of Hard Tissue Biology. 27:185-194
Autor:
Masahiko Hagihara, Tomonoshin Kanazawa, Kei-ichiro Nakamura, Motohisa Shimizu, Keisuke Ohta, Shingo Hirashima
Publikováno v:
Journal of Hard Tissue Biology. 27:95-100
Autor:
Kenichi Suzuki, Yoshitoshi Kasuya, Kensuke Tanaka, Tatsuhiko Sudo, Masahiko Hagihara, Hiroki Umezawa, Kento Yoshioka, Koichiro Tatsumi, Masahiko Hatano, Yusuke Naito
Publikováno v:
Frontiers in Pharmacology
One of the mitogen-activated protein kinases, p38α plays a crucial role in various inflammatory diseases and apoptosis of various types of cells. In this study, we investigated the pathophysiological roles of p38α in spinal cord injury (SCI), using
Autor:
Kensuke Tanaka, Kento Yoshioka, Koichiro Tatsumi, Sadao Kimura, Tatsuhiko Sudo, Hiroki Umezawa, Tetsuo Fujita, Yoshitoshi Kasuya, Kana Namiki, Masahiko Hagihara
Publikováno v:
Laboratory Investigation. 94:1247-1259
Cell-based therapy is recognized as one of potential therapeutic options for lung fibrosis. However, preparing stem/progenitor cells is complicated and not always efficient. Here, we show easily prepared cell populations having therapeutic capacity f
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 92:2-O
Autor:
Hirofumi Matsunaga, Kana Namiki, Yasunori Tokunaga, Kensuke Tanaka, Yoshitoshi Kasuya, Kazuya Murata, Akiyoshi Fukamizu, Akira Sakairi, Jun-Dal Kim, Manabu Shigetomi, Shibakawa Nobuhiko, Tatsuhiko Sudo, Sadao Kimura, Yukinori Wada, Naoki Tokuhara, Junji Ishida, Motohisa Shimizu, Kento Yoshioka, Masahiko Hagihara
Publikováno v:
Journal of Biological Chemistry. 287:24228-24238
One of the mitogen-activated protein kinases, p38, has been found to play a crucial role in various inflammatory responses. In this study, we analyzed the roles of p38α in multiple sclerosis, using an animal model, experimental autoimmune encephalom
Autor:
Stuart L. Schreiber, Masahiko Hagihara
Publikováno v:
ChemInform. 23
Autor:
Tetsushi Katsube, Hiroto Kashiwase, Kaoru Shimada, Tomoaki Komai, Masahiko Hagihara, Tomio Kimura, Takashi Nishigaki, Kenji Momota, Toshinori Ohmine, Satoshi Kimura
Publikováno v:
ChemInform. 31
Synthesis and anti-HIV activity of a series of novel arylpiperazinyl fluoroquinolones are reported. In the SAR study, the aryl substituents on the piperazine nitrogen were found to play an important role for the anti-HIV-1 activity. A few of the comp
Genetic and Pharmacological Inhibition of p38α Improves Locomotor Recovery after Spinal Cord Injury.
Autor:
Hiroki Umezawa, Yusuke Naito, Kensuke Tanaka, Kento Yoshioka, Kenichi Suzuki, Tatsuhiko Sudo, Masahiko Hagihara, Masahiko Hatano, Koichiro Tatsumi, Yoshitoshi Kasuya
Publikováno v:
Frontiers in Pharmacology; 2/17/2017, Vol. 8, p1-10, 10p
Publikováno v:
ChemInform. 34
Synthesis of 2-benzazepines was readily achieved via 7-endo radical cyclization of N-o-bromobenzylitaconamides or N-o-bromobenzylmethacrylamides which were prepared in two steps from commercially available benzaldehydes, amines, and alpha,beta-unsatu