Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Masaharu Urakaze"'
Autor:
Masaharu Urakaze, Chikaaki Kobashi, Yukihiro Satou, Kouichi Shigeta, Masahiro Toshima, Masatoshi Takagi, Jiro Takahashi, Hiroshi Nishida
Publikováno v:
Nutrients, Vol 13, Iss 12, p 4381 (2021)
Astaxanthin (ASTX) is an antioxidant agent. Recently, its use has been focused on the prevention of diabetes and atherosclerosis. We examined the effects of astaxanthin supplementation for 12 weeks on glucose metabolism, glycemic control, insulin sen
Externí odkaz:
https://doaj.org/article/705f8663496c4673919e9ac58f4b705a
Autor:
Kouichi Shigeta, Masaharu Urakaze, Mitsunori Nishida, Chikaaki Kobashi, Jiro Takahashi, Masahiro Toshima, Yukihiro Satou, Masatoshi Takagi
Publikováno v:
Diabetes. 67
Astaxanthin (ASTX) is a xanthophyll carotenoid produced by Haemococcus pluvialis, and is found in microalgae, plankton, krill and other seafood. ASTX has strong antioxidant activity, which is an attractive nutraceutical for further investigation in d
Autor:
Masakiyo Sasahara, Kenta Kambara, Kazuyuki Tobe, Yuji Matsuya, Tomomi Ichikawa, Toshiro Miwa, Isao Usui, Toru Yamada, Ryuji Hayashi, Kensuke Suzuki, Masaharu Urakaze, Shoko Matsui, Shingo Imanishi, Yukiko Koshimizu, Seisuke Okazawa, Yu Yamazaki, Minehiko Inomata
Publikováno v:
Respirology. 18:332-339
Background and objective: In asthma, reduced histone deacetylase activity and enhanced histone acetyltransferase activity in the lungs have been reported. However, the precise function of Sirtuin 1 (Sirt1), a class III histone deacetylase, and the ef
Autor:
Kouichi Shigeta, Tadashi Ikeda, Kanako Motoyoshi, Emiri Muranaka, Yukihiro Satou, Masaharu Urakaze, Chikaaki Kobashi
Publikováno v:
Journal of Diabetes & Metabolism.
An 18-year old Japanese woman with thirst, weight loss and palpitations for a few weeks’ duration was admitted. Her diagnosis was diabetic ketoacidosis with acute-onset type 1 diabetes (T1D) and Graves’ disease (GD) (autoimmune polyglandular synd
Autor:
Arshad Mahmood, Masaharu Urakaze, Yu Yamazaki, Takeshi Oya, Ichiro Kato, Hiroshi Okamoto, Hikari Suzuki, Kazuyuki Tobe, Shiho Fujisaka, Masashi Kobayashi, Satoko Senda, Isao Usui, Shin Takasawa, Yukiko Kanatani, Yoko Ishii, Masakiyo Sasahara
Publikováno v:
Diabetologia. 54:2953-2962
Aims/hypothesis The activation of platelet-derived growth factor receptor-β (PDGFR-β) signalling is increased in the glomeruli and tubules of diabetic animals. In this study, we examined the role of PDGFR-β signalling during the development of dia
Autor:
Hiroki Mano, Oliver Vugrek, Masaharu Urakaze, Hirofumi Ogawa, Tomoharu Gomi, Hirofumi Taki, Kouichiro Shinoda, Isao Usui, Bryan Knuckley, Tatsurou Miyahara, Hisashi Mori, Eiji Sugiyama, Ayumi Tanaka, Hiroyuki Hounoki, Tetsuya Ishimoto, Paul R. Thompson, Kazuyuki Tobe, Ran Inoue, Kazuya Hirata
Publikováno v:
Advances in Bioscience and Biotechnology
The murine peptidylarginine deiminase (PAD) has five isoforms encoded by different genes and partici- pates in a variety of cellular functions through the citrullination of target proteins. The crystal structure of human PAD4 with a dimeric form was
Autor:
Yuji Matsuya, Masashi Kobayashi, Hikari Suzuki, Satoko Senda, Isao Usui, Agussalim Bukhari, Yukiko Kanatani, Yu Yamazaki, Masaharu Urakaze, Kazuyuki Tobe, Shiho Fujisaka, Ryuji Hayashi, Koichi Tsuneyama, Shingo Imanishi, Hideo Nemoto, Manabu Ishiki, Kazuya Hirata
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 297:E1179-E1186
Nonalcoholic fatty liver disease (NAFLD) is an abnormal liver metabolism often observed with insulin resistance and metabolic syndrome. Calorie restriction is a useful treatment for NAFLD and reportedly prolongs the life spans of several species in w
Autor:
Kazuyuki Tobe, Masaharu Urakaze, Yoshinori Nagai, Masashi Kobayashi, Shiho Fujisaka, Isao Usui, Koichi Tsuneyama, Masashi Ikutani, Agussalim Bukhari, Kiyoshi Takatsu, Yukiko Kanatani, Takeshi Oya
Publikováno v:
Diabetes
OBJECTIVE To characterize the phenotypic changes of adipose tissue macrophages (ATMs) under different conditions of insulin sensitivity. RESEARCH DESIGN AND METHODS The number and the expressions of marker genes for M1 and M2 macrophages from mouse e
Autor:
Satoko Senda, Minoru Iwata, Akira Satoh, Isao Usui, Norel Dim Ak, Atsuko Takano, Michiyo Takata, Toshiyasu Sasaoka, Katsuya Yamazaki, Shiho Murakami, Haruo Hachiya, Shiho Fujisaka, Masashi Kobayashi, Masaharu Urakaze, Rie Temaru, Yu Yamazaki
Publikováno v:
Diabetes Research and Clinical Practice. 77:210-214
Telmisartan, a new angiotensin II type 1 receptor blocker (ARB), was recently reported to stimulate PPARgamma, and stronger effects of Telmisartan on insulin sensitivity has been expected than the class effect of ARB. In the present study, we examine
Autor:
Ken Ishizuka, Shiho Fujisaka, Masaharu Urakaze, Tetsuji Naka, Tadamitsu Kishimoto, Tetsuro Haruta, Yukiko Kanatani, Masashi Kobayashi, Isao Usui, Agussalim Bukhari
Publikováno v:
Diabetes. 56:795-803
Pioglitazone is widely used for the treatment of diabetic patients with insulin resistance. The mechanism of pioglitazone to improve insulin sensitivity is not fully understood. Recent studies have shown that the induction of suppressor of cytokine s