Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Masaharu Takemura"'
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Giant viruses, categorized under Nucleocytoviricota, are believed to exist ubiquitously in natural environments. However, comprehensive reports on isolated giant viruses remain scarce, with limited information available on unrecoverable strains, vira
Externí odkaz:
https://doaj.org/article/357dfbfa40854e95bfb217ad9b2e664b
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
ABSTRACT Viruses of the phylum Nucleocytoviricota, or nucleo-cytoplasmic large DNA viruses (NCLDVs), undergo a cytoplasmic or nucleo-cytoplasmic cycle, the latter of which involves both nuclear and cytoplasmic compartments to proceed viral replicatio
Externí odkaz:
https://doaj.org/article/c701a28dbaf94661b1bbc29cfe6ea28b
Autor:
Sho Fukaya, Masaharu Takemura
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 1 (2021)
ABSTRACT Most virus-infected cells show morphological and behavioral changes, which are called cytopathic effects. Acanthamoeba castellanii, an abundant, free-living protozoan, serves as a laboratory host for some viruses of the phylum Nucleocytoviri
Externí odkaz:
https://doaj.org/article/8d33542ac95a41fabedbd3817bc38cb8
Autor:
Masaharu Takemura
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
The mechanistic evolutionary origin of the eukaryotic cell nucleus remains unknown. Among several plausible hypotheses, the most controversial is that large DNA viruses, such as poxviruses, led to the emergence of the eukaryotic cell nucleus. Several
Externí odkaz:
https://doaj.org/article/356e06c9558840f6a9444d1470147ddb
Publikováno v:
Frontiers in Microbiology, Vol 10 (2020)
Tracking cell motility is a useful tool for the study of cell physiology and microbiology. Although phase-contrast microscopy is commonly used, the existence of optical artifacts called “halo” and “shade-off” have inhibited image analysis of
Externí odkaz:
https://doaj.org/article/c93f657bcf7245c2a0ebfa999f67db55
Autor:
Keita Aoki, Reika Hagiwara, Motohiro Akashi, Kenta Sasaki, Kazuyoshi Murata, Hiroyuki Ogata, Masaharu Takemura
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
The family Marseilleviridae, defined as a group of icosahedral double-stranded DNA viruses with particle size of approximately 250 nm and genome size of 350–380 kbp, belongs to the nucleo-cytoplasmic family of large DNA viruses. The family Marseill
Externí odkaz:
https://doaj.org/article/bfcabbc67b4a41079f994b05b3af519b
Autor:
Motohiro Akashi, Masaharu Takemura
Publikováno v:
Viruses, Vol 11, Iss 3, p 267 (2019)
The detailed mechanisms of replication initiation, termination and segregation events were not yet known in Acanthamoeba polyphaga mimivirus (APMV). Here, we show detailed bioinformatics-based analyses of chromosomal replication in APMV from initiati
Externí odkaz:
https://doaj.org/article/adb64a519a044e3ea0d2a0cc981b8183
Autor:
Yoshiyuki Mizushina, Daisuke Manita, Toshifumi Takeuchi, Yuko Kumamoto-Yonezawa, Yuki Matsui, Fumio Sugawara, Masaharu Takemura, Hirosato Takikawa, Hiromi Yoshida, Mitsuru Sasaki
Publikováno v:
Molecules, Vol 14, Iss 1, Pp 102-121 (2008)
We previously isolated a novel natural product, designated kohamaic acid A (KA-A, compound 1), as an inhibitor of the first cleavage of fertilized sea urchin eggs, and found that this compound could selectively inhibit the activities of mammalian DNA
Externí odkaz:
https://doaj.org/article/44bf22b40a8749d2b90b14658a8c831d
Autor:
Yoshiyuki Mizushina, Xianai Xu, Chikako Murakami, Toshio Okano, Masaharu Takemura, Hiromi Yoshida, Kengo Sakaguchi
Publikováno v:
Journal of Pharmacological Sciences, Vol 92, Iss 3, Pp 283-290 (2003)
As described previously (H. Togashi et al. Biochem Pharmacol. 1998;56:583–590), the irradiated products of provitamin D2 (ergosterol) inhibit the activities of eukaryotic DNA polymerases. In this report, therefore, we investigated whether vitamin D
Externí odkaz:
https://doaj.org/article/54dcc86120c0422baf720575370ef852
Publikováno v:
Microbiology Spectrum. 11
In this study, we quantitatively revealed how long the increase in host cell size or the increase in host nucleus size occurs after infection with giant viruses, especially medusavirus. To understand the underlying mechanism, we performed image analy