Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Masaharu Nagashima"'
Autor:
Michishige Terasaki, Munenori Hiromura, Yusaku Mori, Kyoko Kohashi, Masaharu Nagashima, Hideki Kushima, Takuya Watanabe, Tsutomu Hirano
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143396 (2015)
Direct associations between hyperglycemia and atherosclerosis remain unclear. We investigated the association between the amelioration of glycemia by sodium-glucose cotransporter 2 inhibitors (SGLT2is) and macrophage-driven atherosclerosis in diabeti
Externí odkaz:
https://doaj.org/article/48775c39159c47789d62c322366a2668
Autor:
Michishige Terasaki, Masaharu Nagashima, Kyoko Nohtomi, Kyoko Kohashi, Masako Tomoyasu, Kyoko Sinmura, Yukinori Nogi, Yuki Katayama, Kengo Sato, Fumiko Itoh, Takuya Watanabe, Tsutomu Hirano
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70933 (2013)
AIM: Several recent reports have revealed that dipeptidyl peptidase (DPP)-4 inhibitors have suppressive effects on atherosclerosis in apolipoprotein E-null (Apoe (-/-)) mice. It remains to be seen, however, whether this effect stems from increased le
Externí odkaz:
https://doaj.org/article/7fd894710c1847b1afcf95b84cb1df0d
Autor:
Yukinori Nogi, Masaharu Nagashima, Michishige Terasaki, Kyoko Nohtomi, Takuya Watanabe, Tsutomu Hirano
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35683 (2012)
AIM:We recently reported that glucose-dependent insulinotropic polypeptide (GIP) prevents the development of atherosclerosis in apolipoprotein E-null (Apoe(-/-)) mice. GIP receptors (GIPRs) are found to be severely down-regulated in diabetic animals.
Externí odkaz:
https://doaj.org/article/d1e42133f920401ea810541d3fd346ab
Autor:
Masaharu Nagashima
Publikováno v:
Asia-Pacific Journal of Regional Science. 2:243-255
The purpose of this paper is to re-examine the Harris–Todaro model and Todaro paradox in developing countries. Specifically, we address the question of whether new job creation in urban areas always increases urban unemployment. The results of this
Autor:
Kyoko Kohashi, Michishige Terasaki, Masako Tomoyasu, Tsutomu Hirano, Akira Miyazaki, Joo-ri Kim-Kaneyama, Yukinori Nogi, Masaharu Nagashima, Kyoko Shinmura
Publikováno v:
The Showa University Journal of Medical Sciences. 26:191-199
Our group previously demonstrated the suppressive effect of glucagon-like peptide-1(GLP-1)on macrophage-driven atherosclerosis in apolipoprotein E-de�- cient (apoE / )mice. In the present study we investigated the suppressive effect of GLP-1 on
Autor:
Yuji Haga, Masaharu Nagashima, Masafumi Koga, Hiroko Ijima, Ayako Miyazaki, Hideaki Jinnouchi, Kazuyuki Hamaguchi, Satoshi Ohguni
Publikováno v:
Diabetology International. 2:202-207
Aims Hb Toranomon [β112 (G14) Cys → Try] was the variant hemoglobin first reported by Harano et al. (Hemoglobin 20:361–369, 1996). Since 2004 there have been successive reports of Hb Toranomon based on abnormal HbA1c levels measured by high-perf
Autor:
Kengo Sato, Yoshitaka Iso, Tsutomu Hirano, Fumiko Itoh, Masayoshi Shichiri, Takuya Watanabe, Masaharu Nagashima
Publikováno v:
Journal of the American Society of Hypertension. 5:359-365
Human salusin-α and -β are related peptides of 28 and 20 amino acids, respectively, produced from the same precursor, prosalusin. Salusin-β exerts more potent mitogenic effects on human vascular smooth muscle cells (VSMCs) and fibroblasts than sal
Autor:
Kyoko Nohtomi, Akira Miyazaki, Michishige Terasaki, Masaharu Nagashima, Takuya Watanabe, Joo-ri Kim-Kaneyama, Masako Tomoyasu, Tsutomu Hirano
Publikováno v:
Diabetologia
Aims/hypothesis Several lines of evidence suggest that incretin-based therapies suppress the development of cardiovascular disease in type 2 diabetes. We investigated the possibility that glucagon-like peptide-1 (GLP-1) and glucose-dependent insulino
Autor:
Mitsuru Adachi, Takuya Watanabe, Masaharu Nagashima, Yuji Shiraishi, Hiroyuki Itabe, Rina Kato, Shigeki Hongo, Akira Miyazaki, Tsutomu Hirano, Toshiaki Suguro
Publikováno v:
Journal of Hypertension. 26:1955-1965
Objective Our recent studies have indicated that urotensin II, the most potent vasoconstrictor peptide identified to date, potentiates human macrophage foam cell formation and vascular smooth muscle cell proliferation, and its levels are increased in
Publikováno v:
Hypertension Research. 31:127-133
It remains open to debate whether hyperinsulinemia leads to the development of hypertension. We addressed this issue by investigating the effect of chronic insulin infusion on blood pressure and related parameters in hypertensive fructose-fed rats. R