Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Masafumi Shionyu"'
Autor:
Kaoru Nomura, Shoko Mori, Kohki Fujikawa, Tsukiho Osawa, Shugo Tsuda, Kumiko Yoshizawa-Kumagaye, Shun Masuda, Hideki Nishio, Taku Yoshiya, Takao Yoda, Masafumi Shionyu, Tsuyoshi Shirai, Ken-ichi Nishiyama, Keiko Shimamoto
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Non-proteinaceous components in membranes regulate membrane protein insertion cooperatively with proteinaceous translocons. An endogenous glycolipid in the Escherichia coli membrane called membrane protein integrase (MPIase) is one such comp
Externí odkaz:
https://doaj.org/article/c4b649d714414d0ba65ed930bfcd743a
Autor:
Atsushi Hijikata, Clara Shionyu‐Mitsuyama, Setsu Nakae, Masafumi Shionyu, Motonori Ota, Shigehiko Kanaya, Takatsugu Hirokawa, Shogo Nakajima, Koichi Watashi, Tsuyoshi Shirai
Publikováno v:
FEBS Open Bio, Vol 12, Iss 1, Pp 285-294 (2022)
Cepharanthine (CEP) is a natural biscoclaurine alkaloid of plant origin and was recently demonstrated to have anti‐severe acute respiratory syndrome coronavirus 2 (anti‐SARS‐CoV‐2) activity. In this study, we evaluated whether natural analogu
Externí odkaz:
https://doaj.org/article/107db267d382427094cc9f1a9c93c0be
Current status of structure-based drug repurposing against COVID-19 by targeting SARS-CoV-2 proteins
Autor:
Atsushi Hijikata, Clara Shionyu, Setsu Nakae, Masafumi Shionyu, Motonori Ota, Shigehiko Kanaya, Tsuyoshi Shirai
Publikováno v:
Biophysics and Physicobiology, Vol 18 (2021)
More than one and half years have passed, as of August 2021, since the COVID-19 caused by the novel coronavirus named SARS-CoV-2 emerged in 2019. While the recent success of vaccine developments likely reduces the severe cases, there is still a stron
Externí odkaz:
https://doaj.org/article/f3e93de53051417d91e2241d78485984
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract The inheritance modes of pathogenic missense mutations are known to be highly associated with protein structures; recessive mutations are mainly observed in the buried region of protein structures, whereas dominant mutations are significantl
Externí odkaz:
https://doaj.org/article/f36a28c1ef944b89891155264aaa0f6e
Autor:
Ikuko Nakamae, Tsumoru Morimoto, Hiroki Shima, Masafumi Shionyu, Hisayo Fujiki, Noriko Yoneda-Kato, Takashi Yokoyama, Shigehiko Kanaya, Kiyomi Kakiuchi, Tsuyoshi Shirai, Edy Meiyanto, Jun-ya Kato
Publikováno v:
Molecules, Vol 24, Iss 22, p 4067 (2019)
Background: Curcumin has been shown to exert pleiotropic biological effects, including anti-tumorigenic activity. We previously showed that curcumin controls reactive oxygen species (ROS) levels through the ROS metabolic enzymes, to prevent tumor cel
Externí odkaz:
https://doaj.org/article/be5359af826141468328aa963c006989
Autor:
Shoko Mori, Kaoru Nomura, Kohki Fujikawa, Tsukiho Osawa, Masafumi Shionyu, Takao Yoda, Tsuyoshi Shirai, Shugo Tsuda, Kumiko Yoshizawa-Kumagaye, Shun Masuda, Hideki Nishio, Taku Yoshiya, Sonomi Suzuki, Maki Muramoto, Ken-ichi Nishiyama, Keiko Shimamoto
Publikováno v:
ACS Chemical Biology. 17:609-618
Inducing newly synthesized proteins to appropriate locations is an indispensable biological function in every organism. Integration of proteins into biomembranes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a76476ae3dd084adb03b9ddedea7d973
https://doi.org/10.1021/acschembio.1c00882
https://doi.org/10.1021/acschembio.1c00882
Autor:
Motonori Ota, Clara Shionyu-Mitsuyama, Masafumi Shionyu, Shigehiko Kanaya, Atsushi Hijikata, Setsu Nakae, Tsuyoshi Shirai
Publikováno v:
FEBS Letters
Febs Letters
Febs Letters
The World Health Organization (WHO) has declared the coronavirus disease 2019 (COVID-19) caused by the novel coronavirus SARS-CoV-2 a pandemic. There is, however, no confirmed anti-COVID-19 therapeutic currently. In order to assist structure-based di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65067f9d4d1cc8448514d41692b7a2ac
https://doi.org/10.1002/1873-3468.13806
https://doi.org/10.1002/1873-3468.13806
Autor:
Clara Shionyu-Mitsuyama, Takatsugu Hirokawa, Atsushi Hijikata, Tsuyoshi Shirai, Setsu Nakae, Motonori Ota, Koichi Watashi, Masafumi Shionyu, Shogo Nakajima, Shigehiko Kanaya
Cepharanthine is a natural of plant origin, and recently demonstrated to have anti-SARS-CoV-2 activity. In order to evaluate the other natural analogues as a potential COVID-19 drug, a total of 24 compounds resembling cepharanthine were extracted fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::679d53955c1d089597586f3fd1ffb4fc
https://doi.org/10.33774/chemrxiv-2021-mcf3k
https://doi.org/10.33774/chemrxiv-2021-mcf3k
Current status of structure-based drug repurposing against COVID-19 by targeting SARS-CoV-2 proteins
Autor:
Masafumi Shionyu, Shigehiko Kanaya, Clara Shionyu, Motonori Ota, Setsu Nakae, Atsushi Hijikata, Tsuyoshi Shirai
Publikováno v:
Biophysics and Physicobiology, Vol 18 (2021)
Biophysics and Physicobiology
Biophysics and Physicobiology
More than one and half years have passed, as of August 2021, since the COVID-19 caused by the novel coronavirus named SARS-CoV-2 emerged in 2019. While the recent success of vaccine developments likely reduces the severe cases, there is still a stron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c9c7aba9d79135cd0c7e3e37663651
https://doaj.org/article/f3e93de53051417d91e2241d78485984
https://doaj.org/article/f3e93de53051417d91e2241d78485984
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 86:644-653
The nacreous layer of pearl oysters is one of the major biominerals of commercial and industrial interest. Jacalin-related lectins, including PPL3 isoforms, are known to regulate biomineralization of the Pteria penguin pearl shell, although the molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::debccdaa9dd852ee53215041f5a7eac4
https://doi.org/10.1002/prot.25491
https://doi.org/10.1002/prot.25491