Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Masafumi Shimokawa"'
1
Study on Horizon Scanning by Citation Network Analysis and Text Mining: A Focus on Drug Development Related to T Cell Immune Response
Autor: Masafumi Shimokawa, Mayumi Shikano, Hajime Sasaki, Erika Fujii, Masashi Honma, Hiroko Yamano, Takuya Takata
Publikováno v: Therapeutic Innovation & Regulatory Science
Certain innovative technologies applied to medical product development require novel evaluation approaches and/or regulations. Horizon scanning for such technologies will help regulators prepare, allowing earlier access to the product for patients an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a23246d31e7277577b15bf0f39fd9ef
http://europepmc.org/articles/PMC8608232
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2
Future development of artificial organs related with cutting edge emerging technology and their regulatory assessment: PMDA’s perspective
Autor: Nobuhiro Handa, Yasuhiro Fujiwara, Rika Wakao, Shuichi Mochizuki, Masafumi Shimokawa, Hiroyuki Arai
Publikováno v: Journal of Artificial Organs. 23:203-206
Future development of innovative artificial organs is closely related with cutting edge emerging technology. These technologies include brain machine or computer interface, organs made by three dimensional bioprinting, organs designed from induced-pl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec150ec0aea79a3afff89f30bf5026a
https://doi.org/10.1007/s10047-020-01161-4
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3
Postmarketing all-case surveillance trends and contribution to safety measures of drugs approved in Japan: a cross-sectional survey in 1999-2019
Autor: Minami Nakao, Yuri Nakamura, Masafumi Shimokawa, Hideki Maeda
Publikováno v: International journal of clinical pharmacy.
Background Postmarketing all-case surveillance (PACS) is a safety monitoring activity predominantly conducted for drugs with few domestic clinical trials, orphan drugs, or anticancer drugs that potentially cause serious adverse events. Aim This study
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58616b5b8ab9e10362169e6980ff8ee0
https://pubmed.ncbi.nlm.nih.gov/36323961
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5
PMDA's Vision for Horizon Scanning of Emerging Technologies Potentially Relevant to the Development of New Medical Products: The Regulatory Challenge
Autor: Hiroyuki Arai, Daisaku Sato, Masafumi Shimokawa, Rika Wakao
Publikováno v: Clinical pharmacology and therapeutics. 109(2)
A key goal of regulatory agencies for medical products is to make innovative products available to patients and the medical community in a timely manner in order to improve the quality of public health and health care. Thus, regulators must respond q
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cdebaa5ceadd2fe380330fa3fb3cc8
https://pubmed.ncbi.nlm.nih.gov/33469964
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6
Neurotoxic Convulsions Induced by Histamine H2Receptor Antagonists in Mice
Autor: Junichi Kawakami, Masafumi Shimokawa, Koujirou Yamamoto, Yasufumi Sawada, Tatsuji Iga
Publikováno v: Toxicology and Applied Pharmacology. 136:317-323
Convulsive potency was evaluated to investigate the mechanism of neurotoxic convulsion induced by histamine H2 receptor antagonists (H2 blockers). Four H2 blockers, cimetidine (721-1236 nmol), ranitidine (477-954 nmol), famotidine (7.4-44 nmol), and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d23f593594d23e11fcb02b92bc5913
https://doi.org/10.1006/taap.1996.0038
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7
[Untitled]
Autor: Yasufumi Sawada, Masafumi Shimokawa, Tatsuji Iga, Junichi Kawakami, Koujirou Yamamoto
Publikováno v: Pharmaceutical Research. 11:1519-1523
We investigated the effect of acute renal and hepatic dysfunction on the neurotoxicity of ranitidine, a histamine H2 receptor antagonist. Experimental acute hepatic and renal dysfunction in mice were produced by i.p. injection of uranyl nitrate (UN)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::437fe278bce4b1aa50daecb7c70ab81c
https://doi.org/10.1023/a:1018933031526
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9
Inhibition of GABAA receptor-mediated current responses by enoxacin (new quinolone) and felbinac (non-steroidal anti-inflammatory drug) in Xenopus oocytes injected with mouse-brain messenger RNA
Autor: Junichi Kawakami, Koujirou Yamamoto, Atsushi Asanuma, Keiji Yanagisawa, Masafumi Shimokawa, Yasufumi Sawada, Tatsuji Iga
Publikováno v: Biological and Pharmaceutical Bulletin. 16:726-728
The convulsant interaction between enoxacin (ENX), a new quinolone antibacterial agent (NQ), and felbinac (FLB), a non-steroidal anti-inflammatory drug (NSAID), in vivo was reproduced as the change of GABA-induced current response in Xenopus oocytes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98ec3151aa2b6caec538596994cff22
https://doi.org/10.1248/bpb.16.726
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10
Neurotoxic study of H2 antagonists using Xenopus oocytes injected with mouse-brain mRNA
Autor: Yasufumi Sawada, Koujirou Yamamoto, Tatsuji Iga, Keiji Yanagisawa, Atsushi Asanuma, Junichi Kawakami, Masafumi Shimokawa
Publikováno v: Biologicalpharmaceutical bulletin. 20(9)
To clarify the dominant mechanism for the convulsant activity of H 2 antagonists, the effects of an H 2 antagonist, cimetidine, on membrane currents induced by various agonists were investigated. In Xenopus oocytes injected with mouse-brain mRNA, ace
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8837cb2f62a4e688e4ee43e78af1deba
https://pubmed.ncbi.nlm.nih.gov/9331993
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