Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Masafumi Kikuchi"'
Autor:
Hayato Yokota, Yumiko Akamine, Mizuki Kobayashi, Takuro Kitabayashi, Misato Horie, Tentaro Endo, Takechiyo Yamada, Masafumi Kikuchi
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 10, Iss 1, Pp 1-6 (2024)
Abstract Background Naldemedine is an orally available peripherally acting μ-opioid receptor antagonist approved to treat opioid-induced constipation (OIC). It is contraindicated for patients with known or suspected gastrointestinal obstruction to p
Externí odkaz:
https://doaj.org/article/67ae06cdfc84401493f0fa958bd84671
Autor:
Hayato Yokota, Ruriko Asahi, Yumiko Akamine, Mizuki Kobayashi, Hiyu Wakabayashi, Sho Sakamoto, Yuji Okuda, Kazuhiro Sato, Katsutoshi Nakayama, Masafumi Kikuchi
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract Background Anamorelin, a drug to treat cancer cachexia, binds to ghrelin receptors and improves body weight and appetite. In clinical trials in Japan, patients experienced a 10.7% frequency of stimulant conduction system depression as a seve
Externí odkaz:
https://doaj.org/article/29a2149f1da5400eae046b40c766a517
Autor:
Masaki Kumondai, Reika Ogawa, Nagomi Hayashi, Yurika Ishida, Hanae Oshikiri, Yuji Sato, Masafumi Kikuchi, Yu Sato, Toshihiro Sato, Masamitsu Maekawa, Nariyasu Mano
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract Lenvatinib (LEN), a multitarget tyrosine kinase inhibitor used in various cancer treatments, is mainly metabolized by cytochrome P450 3A (CYP3A) enzymes. The importance of therapeutic drug monitoring (TDM) in patients administered LEN has be
Externí odkaz:
https://doaj.org/article/3c3b7eda38744636833b54cae65ec9d1
Autor:
Yu Sato, Hiroki Kondo, Yuji Sato, Ai Abe, Masafumi Kikuchi, Toshihiro Sato, Masaki Kumondai, Kohei Yoshikawa, Yoshihiro Hayakawa, Masamitsu Maekawa, Nariyasu Mano
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1138 (2024)
Therapeutic drug monitoring (TDM) is a personalized treatment approach that involves optimizing drug dosages based on patient-specific factors, such as drug plasma concentrations, therapeutic efficacy, or adverse reactions. The plasma concentration o
Externí odkaz:
https://doaj.org/article/797592a7facb4fbb992499f588035371
Publikováno v:
Open Ceramics, Vol 16, Iss , Pp 100459- (2023)
Strontium-substituted apatite has been proposed as a promising material for osteoporosis treatment. Several synthesis methods have been attempted in the past. In this study, we investigated a method known as the mechanochemical synthesis method. Char
Externí odkaz:
https://doaj.org/article/1a54204ff2c9428c84949d26552ad59d
Autor:
Kentaro Tajima, Tomofumi Ishikawa, Masami Tsuchiya, Masafumi Kikuchi, Taku Obara, Nariyasu Mano
Publikováno v:
Pharmacoepidemiology, Vol 2, Iss 1, Pp 13-25 (2023)
We aimed to evaluate the adverse birth outcomes of anticancer drug prescription during pregnancy using a Japanese claims database from 2005 to 2019. We applied validated claims-based algorithms to identify pregnant women with birth outcomes, and eval
Externí odkaz:
https://doaj.org/article/b08fdb97dc1544cfb2c746eae95f80cf
Autor:
Tensei Hirasawa, Masafumi Kikuchi, Shinya Takasaki, Masaki Kumondai, Yu Sato, Toshihiro Sato, Eishi Imoto, Yoshihiro Hayakawa, Masamitsu Maekawa, Nariyasu Mano
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e16926- (2023)
Many types of oral molecular-targeted anticancer drugs are clinically used in cancer genomic medicine. Combinations of multiple molecular-targeted anticancer drugs are also being investigated, expecting to prolong the survival of patients with cancer
Externí odkaz:
https://doaj.org/article/5548934ceb984d27b8cf4fd6c31ce6d8
Autor:
Naoto Ishikawa, Hanae Oshikiri, Shinya Takasaki, Masafumi Kikuchi, Taku Obara, Kazutoshi Akasaka, Masaki Matsuura, Hiroaki Yamaguchi, Nariyasu Mano
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 7, Iss 1, Pp 1-6 (2021)
Abstract Background Renal function and use of concomitant medications should be carefully monitored in patients subjected to treatment with direct oral anticoagulants (DOACs); the dose should be individually designed for each patient. Owing to the co
Externí odkaz:
https://doaj.org/article/8fa8e76eeebb4069a6a8f8c9fc5b774b
Autor:
Shinya Takasaki, Hiroaki Yamaguchi, Yoshihide Kawasaki, Masafumi Kikuchi, Masaki Tanaka, Akihiro Ito, Nariyasu Mano
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 5, Iss 1, Pp 1-9 (2019)
Abstract Background Everolimus is an oral inhibitor of mammalian target of rapamycin, approved for metastatic renal cell carcinoma (mRCC). Recently, personalized medicine through therapeutic drug monitoring (TDM) is recommended in cancer therapy. In
Externí odkaz:
https://doaj.org/article/dd72e78944d045efb3bf66a0927c84ec
Publikováno v:
Metals, Vol 12, Iss 5, p 861 (2022)
We developed high-strength Ti−Nb−Cu alloys and investigated their grindability. The grindability of each alloy was evaluated based on the volume of metal removed per minute (grinding rate) and on the ratio of the metal volume removed to the volum
Externí odkaz:
https://doaj.org/article/3f465491e1794320b031045e592f4564