Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Masafumi Funakoshi"'
Publikováno v:
Genes and Environment, Vol 45, Iss 1, Pp 1-13 (2023)
Abstract Background DNA oxidatively damaged by reactive oxygen species is repaired by base excision repair (BER) pathway proteins, with DNA glycosylases removing damaged or mismatched bases in the first step of BER. KsgA is a multifunctional protein
Externí odkaz:
https://doaj.org/article/2d4281189e8a4611b31199f69dc722f5
Publikováno v:
Genes and Environment, Vol 39, Iss 1, Pp 1-8 (2017)
Abstract Apurinic/apyrimidinic (AP) sites are one of the most frequent DNA lesions. AP sites inhibit transcription and DNA replication, and induce cell death. AP endonucleases are key enzymes in AP site repair. Several types of AP endonucleases have
Externí odkaz:
https://doaj.org/article/be9332d85cc1484c9c1ec6a0ac0bf410
Autor:
Takahito Moriwaki, Yuichi Kato, Qiu-Mei Zhang-Akiyama, Masafumi Funakoshi, Seiji Kato, Kento Igarashi
Publikováno v:
Genes & Genetic Systems. 94:81-93
Apurinic/apyrimidinic (AP) sites are the most common form of cytotoxic DNA damage. Since AP sites inhibit DNA replication and transcription, repairing them is critical for cell growth. However, the significance of repairing AP sites during early embr
Autor:
Kento, Igarashi, Masafumi, Funakoshi, Seiji, Kato, Takahito, Moriwaki, Yuichi, Kato, Qiu-Mei, Zhang-Akiyama
Publikováno v:
Genesgenetic systems. 94(2)
Apurinic/apyrimidinic (AP) sites are the most common form of cytotoxic DNA damage. Since AP sites inhibit DNA replication and transcription, repairing them is critical for cell growth. However, the significance of repairing AP sites during early embr
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
AP endonuclease deficiency causes cell death and embryonic lethality in mammals. However, the physiological roles of AP endonucleases in multicellular organisms remain unclear, especially after embryogenesis. Here, we report novel physiological roles
Publikováno v:
Genes and Environment, Vol 39, Iss 1, Pp 1-8 (2017)
Genes and Environment
Genes and Environment
Apurinic/apyrimidinic (AP) sites are one of the most frequent DNA lesions. AP sites inhibit transcription and DNA replication, and induce cell death. AP endonucleases are key enzymes in AP site repair. Several types of AP endonucleases have been repo
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 772:46-54
Apurinic/apyrimidinic (AP) sites are the major DNA damage generated continuously even under normal conditions, and inhibit DNA replication/transcription. AP endonucleases are ubiquitous enzymes required for the repair of AP sites and 3' blocking ends
Publikováno v:
Seibutsu Butsuri. 46:S246