Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Masafumi, Shibamori"'
Autor:
Masafumi Shibamori, Masayuki Sato, Naoya Uematsu, Takako Nakashima, Asuka Sato, Yoshiya Yamamura, Hiroyuki Sasabe, Ken Umehara, Kazushi Sakurai
Publikováno v:
Journal of Pharmacological Sciences, Vol 129, Iss 1, Pp 18-25 (2015)
Recent studies have shown that rebamipide, which suppresses reactive oxygen species, prevents chemoradiotherapy-induced oral mucositis in patients with head and neck cancers. However, anticancer action of radiotherapy and chemotherapy is believed to
Externí odkaz:
https://doaj.org/article/a2ba47e155a64a5ca909b85194b78849
Autor:
Hiroyuki Sasabe, Takako Nakashima, Kazushi Sakurai, Masafumi Shibamori, Masayuki Sato, Naoya Uematsu, Ken Umehara, Asuka Sato, Yoshiya Yamamura
Publikováno v:
Journal of Pharmacological Sciences, Vol 129, Iss 1, Pp 18-25 (2015)
Recent studies have shown that rebamipide, which suppresses reactive oxygen species, prevents chemoradiotherapy-induced oral mucositis in patients with head and neck cancers. However, anticancer action of radiotherapy and chemotherapy is believed to
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 347:660-668
Oral mucositis is a frequent and serious side effect in patients who receive radiotherapy for head and neck cancer. The purpose of this study was to develop a noninvasive and quantitative model of oral mucositis in rats, investigate the pathophysiolo
Autor:
Hiroshi Asahara, Hiromi Maruyama, Masafumi Shibamori, Hideki Kawasome, Hirohito Shimizu, Jan Tuckermann, Alexander Rauch, Shigeru Miyaki, Maki Asada, Hironobu Ishiyama
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Laboratory investigation, 91: 203–215
Laboratory investigation, 91: 203–215
Glucocorticoids, such as dexamethasone, have been used as in vitro inducers of adipogenesis. However, the roles of the glucocorticoid receptor (GR) in adipogenesis have not been well characterized yet. Here, we show that inhibition of GR activity usi
Autor:
Kei Takemoto, Masafumi Shibamori, Keiki Ogino, Junna Okuda, Norio Kodama, Yoshiaki Hitomi, Tomoko Takigawa, Yasuhiro Kambayashi, Masayuki Kubo
Publikováno v:
Acta Biochimica Polonica. 53:577-584
In the present study, we investigated how cytochrome c catalyzed the nitration of tyrosine at various pHs. The cytochrome c-catalyzed nitration of tyrosine occurred in proportion to the concentration of hydrogen peroxide, nitrite or cytochrome c. The
Autor:
Masafumi Shibamori, Shigeru Kamiya, Takako Nakashima, Kazushi Sakurai, Satoshi Kurata, Naoya Uematsu, Takako Osaki
Publikováno v:
Journal of Clinical Biochemistry and Nutrition
The effect of rebamipide, a mucosal protective drug, on small intestinal mucosal injury caused by indomethacin was examined using a rat model. Indomethacin administration (10 mg/kg, p.o.) induced intestinal mucosal injury was accompanied by an increa
Autor:
Shouichirou Shibata, Kazuya Shimoda, Ken Takase, Seiichi Okamura, Akitomo Miyamoto, Yoshiyuki Niho, Hisashi Gondo, Masafumi Shibamori, Keiko Nakayama, Kazuo Sekiguchi, Yoshinobu Asano, Takashi Okamura, Akihiko Numata, Kenichi Aoki, Keiichi I. Nakayama, Masakatsu Yamashita, Tadashi Matsuda, Toshinori Nakayama, Kouji Kato, Shinji Kobayashi
Publikováno v:
Immunity. 13(4):561-571
Janus kinases (Jaks) play an important role in signal transduction via cytokine receptors. Tyk2 is a Janus kinase, and we developed tyk2-deficient mice to study the requirement for tyk2 in vivo. Tyk2-deficient mice show no overt developmental abnorma
Autor:
Hironobu Ishiyama, Masafumi Shibamori, Yoshihisa Fujikura, Noriko Takahashi, Da Hong Wang, Keiki Ogino, Tomoko Takigawa, Seiji Hamanishi, Kei Takemoto
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 299(1)
The expression of arginase I has been a focus of research into the pathogenesis of experimental asthma, because arginase deprives nitric oxide synthase (NOS) of arginine and therefore participates in the attenuation of bronchodilators such as nitric
Autor:
Kenichi Imagawa, Takachika Azuma, Yoshihiro Sugiyama, Hidechika Okada, Ken Yamaguchi, Hiroshi Momota, Kyohei Deguchi, Mikio Kikuchi, Miki Aihara, Jiro Hitomi, Masafumi Shibamori, Ozge Alper
Publikováno v:
Japanese Journal of Cancer Research : Gann
With the aim of developing an effective cancer immunotherapy for common epithelial cancer, a new class of bifunctional antibody (BFA) was developed; one arm of this BFA recognized c-erbB-2 gene product, and the other arm recognized CD3 epsilon, a T-c
Autor:
Keiki Ogino, Masafumi Shibamori, Hiroshi Ichimura, Yoshiaki Hitomi, Da Hong Wang, Toshikazu Gondo, Kei Takemoto, Hironobu Ishiyama, Yoshihisa Fujikura, Jiro Takaki, Tomoko Takigawa
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 293(6)
Changes in the expression of arginase and their association with nitrosative stress were investigated using an asthmatic model previously established in NC/Nga mice with mite extract. Mite crude extract (100 μg/day) from Dermatophagoides farinae was