Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Masaaki Tsutsuura"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 103, Iss 4, Pp 347-353 (2007)
CaV1.2 (α1c) is a pore-forming subunit of the voltage-dependent L-type calcium channel and is expressed in many tissues. The β and α2/δ subunits are auxiliary subunits that affect the kinetics and the expression of CaV1.2. In addition to the β a
Externí odkaz:
https://doaj.org/article/2a6d4198a87f4eaeab3db097958f53aa
Publikováno v:
Journal of Pharmacological Sciences, Vol 103, Iss 4, Pp 347-353 (2007)
Ca(V)1.2 (alpha(1c)) is a pore-forming subunit of the voltage-dependent L-type calcium channel and is expressed in many tissues. The beta and alpha(2)/delta subunits are auxiliary subunits that affect the kinetics and the expression of Ca(V)1.2. In a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5191a119b26791280a4d3b96f525e6c7
http://www.sciencedirect.com/science/article/pii/S1347861319342884
http://www.sciencedirect.com/science/article/pii/S1347861319342884
Autor:
Takeshi Kobayashi, Noritsugu Tohse, Masaaki Tsutsuura, Yoichi Yamada, Sumihiko Seki, Naomasa Makita, Masato Nagashima, Yoshinobu Horio
Publikováno v:
Journal of Biological Chemistry. 276:47163-47170
L-type Ca(2+) channels are heteromultimeric and finely tuned by auxiliary subunits in different tissues and regions. Among auxiliary subunits, beta subunit has been shown to play important roles in many functional aspects of Ca(2+) channel. Rat heart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f804e557d07b4c1017ea945f1f31d1
https://doi.org/10.1074/jbc.m108049200
https://doi.org/10.1074/jbc.m108049200
Autor:
Masaaki Tsutsuura, Takeshi Kobayashi, Yoichi Yamada, Kaori Shiratori, Noritsugu Tohse, Mitsuhiro Fukao, Katsumasa Tanimoto
Publikováno v:
Biochemical and biophysical research communications. 360(3)
The beta subunits of voltage-dependent calcium channels bind the pore-forming alpha(1) subunit and play an important role in the regulation of calcium channel function. Recently, we have identified a new splice variant of the beta(4) subunit, which w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b48a05889f75d44b737520b91b7922
https://pubmed.ncbi.nlm.nih.gov/17618603
https://pubmed.ncbi.nlm.nih.gov/17618603
Autor:
Yoichi Yamada, Mitsuhiro Fukao, Masaaki Tsutsuura, Toshihiko Yamashita, Takeshi Kobayashi, Kazutoshi Kameda, Noritsugu Tohse, Masato Nagashima
Publikováno v:
Journal of molecular and cellular cardiology. 40(4)
L-type Ca(2+) channels have a wide tissue distribution and play essential roles in physiological responses. Recent studies have indicated that regulation of L-type Ca(2+) channels involves the assembly of macromolecular signaling complexes such as th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854bba5ded5171c788059897b0234d03
https://pubmed.ncbi.nlm.nih.gov/16483597
https://pubmed.ncbi.nlm.nih.gov/16483597
Autor:
Kazutoshi Kameda, Masato Nagashima, Tomio Abe, Sumihiko Seki, Yoshinori Ito, Yoichi Yamada, Ichiro Sakuma, Mitsuhiro Fukao, Takeshi Kobayashi, Noritsugu Tohse, Hirofumi Hamada, Masaaki Tsutsuura
Publikováno v:
Advances in Electrocardiology 2004.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8054abe5650e908ed919c6f20c3f604c
https://doi.org/10.1142/9789812702234_0069
https://doi.org/10.1142/9789812702234_0069
Autor:
Yoichi Yamada, Sumihiko Seki, Masato Nagashima, Takeshi Kobayashi, Masaaki Tsutsuura, Noritsugu Tohse
Publikováno v:
The Japanese journal of physiology. 54(1)
The excitation-contraction (E-C) coupling system during the development of heart can be investigated because of marked progression in electrophysiology and microfluorescence studies. During the developmental period, Ca 2 + influx mediating the E-C co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db29c23a20433a377a208110b92d78a2
https://pubmed.ncbi.nlm.nih.gov/15040842
https://pubmed.ncbi.nlm.nih.gov/15040842
Autor:
Tomio Abe, Yoshinori Ito, Sumihiko Seki, Masato Nagashima, Ichiro Sakuma, Masaaki Tsutsuura, Noritsugu Tohse, Yoichi Yamada, Hirofumi Hamada, Takeshi Kobayashi
Publikováno v:
Journal of molecular and cellular cardiology. 35(9)
The Ca 2+ -independent, voltage-gated transient outward current ( I to ) displays a marked increase during development of cardiomyocytes. However, the molecular mechanism remained unclear. In rat adult ventricular myocytes, I to can be divided into a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d846d0546076a83068770c22a947fb
https://pubmed.ncbi.nlm.nih.gov/12967630
https://pubmed.ncbi.nlm.nih.gov/12967630
Autor:
Masato Nagashima, Yoichi Yamada, Takeshi Kobayashi, Masaaki Tsutsuura, Sumihiko Seki, Akiyoshi Namiki, Yasuhiro Kamada, Michiaki Yamakage, Noritsugu Tohse
Publikováno v:
European journal of pharmacology. 487(1-3)
We recently cloned the beta(2c) subunit of the L-type Ca(2+) channel as a functional type of beta subunit from the rat heart. In order to clarify the contribution of the beta(2c) subunit to native Ca(2+) channel function, we investigated the single-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be3c41b41e071d5baad66b495e040649
https://pubmed.ncbi.nlm.nih.gov/15033374
https://pubmed.ncbi.nlm.nih.gov/15033374
Autor:
Masato Nagashima, Noritsugu Tohse, Xiangdong Chen, Michiaki Yamakage, Akiyoshi Namiki, Sumihiko Seki, Takeshi Kobayashi, Masaaki Tsutsuura, Yoichi Yamada, Yasuhiro Kamada
Publikováno v:
Biochemical and biophysical research communications. 294(2)
KCNQ1 encodes a pore-forming subunit of potassium channels. Mutations in this gene cause inherited diseases, i.e., Romano-Ward syndrome and Jervell and Lange-Nielsen syndrome. A truncated isoform of KCNQ1 was reported to be expressed physiologically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772968745f7509294155164eac906f52
https://pubmed.ncbi.nlm.nih.gov/12051693
https://pubmed.ncbi.nlm.nih.gov/12051693