Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Masaaki Soma"'
Publikováno v:
Journal of Cardiology. 54:368-374
Summaryω-3 fatty acids, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have beneficial effects on cardiovascular diseases. Cytochrome P-450 (CYP) 2J2 that is expressed in endothelial cells metabolizes arachidonic acids to biolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71b4893bb0fb6f9c726950b450bf0b9
https://doi.org/10.1016/j.jjcc.2009.06.004
https://doi.org/10.1016/j.jjcc.2009.06.004
Autor:
Yasutaka Yamamoto, Yutaka Hirota, Haruaki Ninomiya, Masaaki Soma, Osamu Igawa, Akio Yoshida, Yoshiko Hoshikawa, Ting Y. Kuang, Shunya Koshida, Junichiro Miake, Udin Bahrudin, Goshi Shiota, Yasuaki Shirayoshi, Tomomi Notsu, Shingo Harada, Ichiro Hisatome, Peili Li, Katsumi Higaki, Yasutaka Kurata
Publikováno v:
European Journal of Pharmacology. 604:93-102
We investigated the effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on the stability of Kv1.5 channel protein. The expression and function of Kv1.5 (Kv1.5-FLAG) in transfected African green monkey kidney fibroblast cells as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cebc4e2d644b1d2202e84fe2068dc4ea
https://doi.org/10.1016/j.ejphar.2008.12.016
https://doi.org/10.1016/j.ejphar.2008.12.016
Autor:
Masaaki Soma, Taisuke Jo, Nami Kubota, Takahide Nagase, Taiji Nagata, Haruhito Takano, Toshiaki Nakajima, Hitoshi Oonuma, Atsushi Oguri, T Tsutsumi, Kentaro Meguro, Hiroyuki Imuta
Publikováno v:
British Journal of Pharmacology. 156:420-431
Mandarin translation of abstract Background and purpose: The voltage-gated Na+ channels (Nav) and their corresponding current (INa) are involved in several cellular processes, crucial to metastasis of cancer cells. We investigated the effects of eico
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a07a8a6670af4ae38116faa70243b92
https://doi.org/10.1111/j.1476-5381.2008.00059.x
https://doi.org/10.1111/j.1476-5381.2008.00059.x
Publikováno v:
Fertility and Sterility. 90:1496-1502
Objective To investigate the anti-inflammatory effect of n-3 eicosapentaenoic acid (EPA) compared with n-6 linoleic acid (LA) in an endometriosis rat model. We focused on the relationship between lipid metabolism and inflammatory reactions in endomet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb192e678dc910a25a7b221d35fda893
https://doi.org/10.1016/j.fertnstert.2007.08.014
https://doi.org/10.1016/j.fertnstert.2007.08.014
Autor:
Akira Ogawa, Tetsu Kurokawa, Hiroshi Yoneda, Akira Kudo, Hirosuke Fujisawa, Sei Kobayashi, Satoshi Shirao, Michiyasu Suzuki, Kuniaki Ogasawara, Masaaki Soma, Ichiro Kunitsugu
Publikováno v:
Cerebrovascular Diseases. 26:30-37
Background and Purpose: Rho-kinase (ROK)-mediated Ca2+ sensitization of vascular smooth muscle (VSM) contraction plays a pivotal role in cerebral vasospasm (CV). We previously demonstrated that sphingosylphosphorylcholine (SPC) induces Ca2+ sensitiza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c932fd599d312087692c1b9ef9bdc8
https://doi.org/10.1159/000135650
https://doi.org/10.1159/000135650
Autor:
Noriyasu Morikage, Kimikazu Hamano, Fengling Guo, Masaaki Soma, Satoshi Shirao, Hiroko Kishi, Sei Kobayashi, Takashi Yano, Masafumi Sato, Kensuke Esato
Publikováno v:
Circulation Research. 99:299-306
Hypercholesterolemia is a major risk factor involved in abnormal cardiovascular events. Rho-kinase–mediated Ca 2+ sensitization of vascular smooth muscle (VSM) plays a critical role in vasospasm and hypertension. We recently identified sphingosylph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e5318e56fedc6dd16e967e9a46b6298
https://doi.org/10.1161/01.res.0000235877.33682.e9
https://doi.org/10.1161/01.res.0000235877.33682.e9
Autor:
Masaaki Soma, Takashi Miyauchi, Sohel Zaedi, Iwao Yamaguchi, Subrina Jesmin, Seiji Maeda, Nobutake Shimojo, Kazutaka Aonuma
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 291:H835-H845
The cardiovascular benefit of fish oil in humans and experimental animals has been reported. Endothelin (ET)-1 is a well-known cardiac hypertrophic factor. However, although many studies link a fish oil extract, eicosapentaenoic acid (EPA), to cardia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::919d5c535070aa26c35be445c0ac0953
https://doi.org/10.1152/ajpheart.01365.2005
https://doi.org/10.1152/ajpheart.01365.2005
Eicosapentaenoic Acid Reduces Myocardial Injury Induced by Ischemia and Reperfusion in Rabbit Hearts
Autor:
Masatsugu Hori, Jiyoong Kim, Masaaki Soma, Seiji Takashima, Koichi Node, Tetsuo Minamino, Hiroshi Asanuma, Shoji Sanada, Masafumi Kitakaze, Hisakazu Ogita
Publikováno v:
Journal of Cardiovascular Pharmacology. 41:964-969
Intake of fish oil is known to have cardioprotective effects and reduce cardiovascular mortality. However, it is not widely recognized that eicosapentaenoic acid (EPA), one of the n-3 polyunsaturated fatty acids (PUFAs), exerts beneficial effects aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e248d883f1e6e610a341d85dc4b015
https://doi.org/10.1097/00005344-200306000-00020
https://doi.org/10.1097/00005344-200306000-00020
Autor:
Keigo Chisaki, Toshiaki Nakajima, Takashi Miyauchi, Norio Ohkoshi, Masaaki Soma, Seiji Suzuki, Hirohito Sone, Nobuhiro Yamada, Yukichi Okuda
Publikováno v:
Hypertension Research. 26:655-661
cis-Polyunsaturated fatty acids such as eicosapentaenoic acid (EPA) are the major fatty acids contained in fish oil, and are known to affect the various physiological properties of cell membranes in humans. The present study investigated the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a90ef2b0d3ec34baa364e3851e3d801
https://doi.org/10.1291/hypres.26.655
https://doi.org/10.1291/hypres.26.655
Autor:
Shinsuke Tanaka, Hagemu Shimizu, Michio Sakamaki, Yasuyuki Kunihiro, Minoru Sasaki, Masaaki Soma
Publikováno v:
Japanese Journal of Pharmacoepidemiology/Yakuzai ekigaku. 6:5-28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24086eac40c587769bd86025be5ba5e0
https://doi.org/10.3820/jjpe1996.6.5
https://doi.org/10.3820/jjpe1996.6.5