Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Masaaki Nishiyama"'
Autor:
Atsuki Kawamura, Masaaki Nishiyama
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract CHD8 encodes chromodomain helicase DNA-binding protein 8 and its mutation is a highly penetrant risk factor for autism spectrum disorder (ASD). CHD8 serves as a key transcriptional regulator on the basis of its chromatin-remodeling activity
Externí odkaz:
https://doaj.org/article/f6f45cbfe1794fa3bbd40e089573e5a4
Autor:
Stanislav M. Cherepanov, Maria Gerasimenko, Teruko Yuhi, Kazumi Furuhara, Chiharu Tsuji, Shigeru Yokoyama, Keiichi I. Nakayama, Masaaki Nishiyama, Haruhiro Higashida
Publikováno v:
BMC Neuroscience, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Autism spectrum disorder (ASD) is characterized by the core symptoms of impaired social interactions. Increasing evidence suggests that ASD has a strong genetic link with mutations in chromodomain helicase DNA binding protein 8 (C
Externí odkaz:
https://doaj.org/article/de99fde7873247aa8f3098ce67c1a566
Autor:
Atsuki Kawamura, Yuta Katayama, Wataru Kakegawa, Daisuke Ino, Masaaki Nishiyama, Michisuke Yuzaki, Keiichi I. Nakayama
Publikováno v:
Cell Reports, Vol 35, Iss 1, Pp 108932- (2021)
Summary: Mutations in the gene encoding the chromatin remodeler chromodomain helicase DNA-binding protein 8 (CHD8) are a highly penetrant risk factor for autism spectrum disorder (ASD). Although cerebellar abnormalities have long been thought to be r
Externí odkaz:
https://doaj.org/article/bd1a938c7cc240e8a83c19cfb45ff672
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
The iron-regulated F-box protein FBXL5 regulates iron homeostasis by mediating the degradation of iron regulatory protein 2 (IRP2). Here the authors show that FBXL5 and its regulation of IRP2 are required for HSC self-renewal and reconstitution capab
Externí odkaz:
https://doaj.org/article/32b1e866594148d596b3568030113e20
Publikováno v:
Nature Methods. 19:1286-1294
Oxytocin (OT), a hypothalamic neuropeptide that acts as a neuromodulator in the brain, orchestrates a variety of animal behaviors. However, the relationship between brain OT dynamics and complex animal behaviors remains largely elusive, partly becaus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ab8bdd4594dd7b7571e3c6f77586e9
https://doi.org/10.1038/s41592-022-01597-x
https://doi.org/10.1038/s41592-022-01597-x
Facial expressions are widely recognized as universal indicators of underlying internal states in most species of animals, thereby presenting as a non-invasive measure for predicting physical and mental conditions. Despite the advancement of artifici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68f80fd3d7c22d7f875ddb3f962dcb94
https://doi.org/10.1101/2023.02.17.528923
https://doi.org/10.1101/2023.02.17.528923
Autor:
Masaaki Nishiyama, Yuhei Yamauchi, Hideyuki Shimizu, Akihiro Nita, Yoshiharu Muto, Hirokazu Nakatsumi, Keiichi I. Nakayama
Publikováno v:
Genes to Cells. 25:427-438
All trophoblast subtypes of the placenta are derived from trophoblast stem cells (TSCs). TSCs have the capacity to self-renew, but how the proliferation of these cells is regulated in the undifferentiated state has been largely unclear. We now show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6201b4ba7920dcf19535b5a356d6b663
https://doi.org/10.1111/gtc.12769
https://doi.org/10.1111/gtc.12769
Oxytocin (OT), a hypothalamic neuropeptide that acts as a neuromodulator in the brain, orchestrates a variety of animal behaviors. However, the relationship between brain OT dynamics and complex animal behaviors remains largely elusive, partly becaus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d91f298450ce3282a9fcfffb34c03fb
https://doi.org/10.1101/2021.07.30.454450
https://doi.org/10.1101/2021.07.30.454450
Autor:
Kazuhiko Koike, Toshiro Moroishi, Keiichi I. Nakayama, Masaaki Nishiyama, Kazuya Ichihara, Masaki Mori, Hidetoshi Eguchi, Yuta Katayama, Kyoji Moriya, Koshi Mimori, Yoshiharu Muto, Hideyuki Shimizu
Publikováno v:
The Journal of Experimental Medicine
Hepatocellular iron overload elicited by ablation of the iron-sensing ubiquitin ligase FBXL5 promotes liver carcinogenesis induced by exposure to a chemical carcinogen or hepatitis virus, suggesting that FBXL5 is a previously unrecognized oncosuppres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b75a864b975e7a011338b5155c6fd7d
https://doi.org/10.1084/jem.20180900
https://doi.org/10.1084/jem.20180900
Autor:
Kazumi Furuhara, Teruko Yuhi, Masaaki Nishiyama, Maria Gerasimenko, Keiichi I. Nakayama, Haruhiro Higashida, Stanislav M. Cherepanov, Shigeru Yokoyama, Chiharu Tsuji
Publikováno v:
BMC Neuroscience, Vol 22, Iss 1, Pp 1-13 (2021)
BMC Neuroscience
BMC Neuroscience
Background Autism spectrum disorder (ASD) is characterized by the core symptoms of impaired social interactions. Increasing evidence suggests that ASD has a strong genetic link with mutations in chromodomain helicase DNA binding protein 8 (CHD8), a g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9de29750c399d2b602b60350cde2a40
https://doi.org/10.1186/s12868-021-00631-6
https://doi.org/10.1186/s12868-021-00631-6