Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Masaaki Kimoto"'
Autor:
Toshiaki Aoki, Kensuke Ohnishi, Masaaki Kimoto, Satoshi Fujieda, Kouji Kuramochi, Toshifumi Takeuchi, Atsuo Nakazaki, Nobuo Watanabe, Fumio Sugawara, Takao Arai, Susumu Kobayashi
Publikováno v:
Pharmaceuticals, Vol 3, Iss 4, Pp 1063-1069 (2010)
We developed an efficient, stereoselective synthetic method for the diketopiperazine moiety of neoechinulin A and its derivatives. The intramolecular cyclization at 80 ºC proceeded with minimal racemization of the stereogenic center at C-12 on neoec
Externí odkaz:
https://doaj.org/article/b78c6fa0cc544c91a93abd0b67bfe82e
Autor:
Kensuke Ohnishi, Toshiaki Aoki, Susumu Kobayashi, Fumio Sugawara, Atsuo Nakazaki, Toshifumi Takeuchi, Takao Arai, Masaaki Kimoto, Nobuo Watanabe, Satoshi Fujieda, Kouji Kuramochi
Publikováno v:
Pharmaceuticals, Vol 3, Iss 4, Pp 1063-1069 (2010)
Pharmaceuticals
Volume 3
Issue 4
Pages: 1063-1069
Pharmaceuticals
Volume 3
Issue 4
Pages: 1063-1069
We developed an efficient, stereoselective synthetic method for the diketopiperazine moiety of neoechinulin A and its derivatives. The intramolecular cyclization at 80 ºC proceeded with minimal racemization of the stereogenic center at C-12 on neoec
Autor:
Masaaki Kimoto, Kensuke Ohnishi, Takashi Ohuchi, Susumu Kobayashi, Toshiaki Aoki, Shinji Kamisuki, Fumio Sugawara, Yoshifumi Takeda, Takao Arai, Atsuo Nakazaki, Yoichi Takakusagi, Kouji Kuramochi, Kenji Kuroiwa
Publikováno v:
Synlett. :0677-0680
A total synthesis of neoechinulin A was accomplished with high enantiomeric excess. Our total synthesis of neoechinulin A established the absolute configuration of natural neoechinulin A. The synthetic route features aldol condensation of a 3-formyl