Zobrazeno 1 - 10
of 220
pro vyhledávání: '"Masa-Aki Shibata"'
Autor:
Chisato Terada, Kaho Oh, Ryutaro Tsubaki, Bun Chan, Nozomi Aibara, Kaname Ohyama, Masa-Aki Shibata, Takehiko Wada, Mariko Harada-Shiba, Asako Yamayoshi, Tsuyoshi Yamamoto
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Off-target interactions between antisense oligonucleotides (ASOs) with state-of-the-art modifications and biological components still pose clinical safety liabilities. To mitigate a broad spectrum of off-target interactions and enhance the s
Externí odkaz:
https://doaj.org/article/f91d43d20dee49279cc0568179bd731f
Autor:
Ayana Ikari, Yuko Ito, Kohei Taniguchi, Masa-Aki Shibata, Kosei Kimura, Mitsuhiko Iwamoto, Sang-Woong Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9742 (2024)
Malignant breast cancers pose a notable challenge when it comes to treatment options. Recently, research has implicated extracellular vesicles (EVs) secreted by cancer cells in the formation of a pre-metastatic niche. Small clumps of CD44-positive br
Externí odkaz:
https://doaj.org/article/86a8831e446d444da30d6f7193b93271
Autor:
Jun Arima, Kohei Taniguchi, Nobuhiko Sugito, Kazuki Heishima, Yoshihisa Tokumaru, Yosuke Inomata, Kazumasa Komura, Tomohito Tanaka, Masa-Aki Shibata, Sang-Woong Lee, Yukihiro Akao
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102079- (2023)
Replenishing tumor-suppressor miRNAs (TS-miRNAs) is a potential next-generation nucleic acid–based therapeutic approach. Establishing an effective miRNA delivery system is essential to successful TS-miRNA therapy. To overcome vulnerability to RNA n
Externí odkaz:
https://doaj.org/article/7b66e61b743a46dbb834022e28a5558d
Autor:
Chisato Terada, Kaho Oh, Ryutaro Tsubaki, Bun Chan, Nozomi Aibara, Kaname Ohyama, Masa-Aki Shibata, Takehiko Wada, Mariko Harada-Shiba, Asako Yamayoshi, Tsuyoshi Yamamoto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/aa9e0af933084a88b819bfb9ce7cf440
Autor:
Masa-Aki Shibata, Kohei Taniguchi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7123 (2023)
Cancer metastasis is a common biological phenomenon observed in malignant tumors that can lead to death in affected individuals [...]
Externí odkaz:
https://doaj.org/article/543e3eaeded44859ba9bb4790ed6b62b
Autor:
Minoru Numata, Akane Hirano, Yukika Yamamoto, Michiko Yasuda, Nobuhiko Miura, Kazutoshi Sayama, Masa-Aki Shibata, Tomohiro Asai, Naoto Oku, Noriyuki Miyoshi, Kayoko Shimoi
Publikováno v:
Journal of Circadian Rhythms, Vol 19, Iss 1 (2021)
Epidemiological studies have indicated that a disturbed circadian rhythm resulting from night-shift work is a potential risk factor for breast cancer. However, the mechanism of increased risk of breast cancer by night-shift work remains unclear, and
Externí odkaz:
https://doaj.org/article/04e209f79b64459b8c60ccc245e848e8
Autor:
Tsuyoshi Yamamoto, Chisato Terada, Kaho Oh, Ryutaro Tsubaki, Bun Chan, Nozomi Aibara, Kaname Ohyama, Masa-Aki Shibata, Takehiko Wada, Mariko Harada-Shiba, Asako Yamayoshi
Off-target interactions between antisense oligonucleotides (ASOs) with state-of-the-art modifications and biological components still pose clinical safety liabilities. To prevent both hybridization-dependent and -independent off-target interactions,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e115ec9f52eb3b30c0ab320cc979dbe
https://doi.org/10.21203/rs.3.rs-2762001/v1
https://doi.org/10.21203/rs.3.rs-2762001/v1
Autor:
Masa-Aki Shibata, Mariko Harada-Shiba, Eiko Shibata, Hideki Tosa, Yoshinobu Matoba, Hitomi Hamaoka, Munekazu Iinuma, Yoichi Kondo
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1722 (2019)
Lifestyle choices play a significant role in the etiology of atherosclerosis. Male Apoe−/− mice that develop spontaneous atherosclerotic lesions were fed 0%, 0.3%, and 0.4% mangosteen extracts, composed largely of α-mangostin (MG), for 17 weeks.
Externí odkaz:
https://doaj.org/article/3a9b1c751db3452aa2563de4a46b27a0
Autor:
Kazuhisa Uchiyama, Keitaro Tanaka, Masa-Aki Shibata, Hiroki Hamamoto, Kohei Taniguchi, Yosuke Inomata, Tomo Tominaga, Junji Okuda, Wataru Osumi, Kazumasa Komura, Masashi Yamamoto
Publikováno v:
Cancer Science
Recently, the feasibility of real‐time indocyanine green (ICG) fluorescence imaging–guided complete mesocolic excision in colon cancer surgery has been demonstrated; however, its application to the evaluation of lymphatic flow in widespread lymph
Publikováno v:
Cancer Science
Accumulating evidence on the association of VEGF‐C with lymphangiogenesis and lymph node metastasis implicates lymphatic vessels as a potential target in anti‐cancer therapy. To evaluate whether blocking VEGF‐C and VEGFR‐3 signaling can inhib