Výsledky vyhledávání

A glycosyltransferase gene signature to detect pancreatic ductal adenocarcinoma patients with poor prognosis

Autor: Mohamed Abd-El-Halim, Yousra, El Kaoutari, Abdessamad, Silvy, Françoise, Rubis, Marion, Bigonnet, Martin, Roques, Julie, Cros, Jérôme, Nicolle, Rémy, Iovanna, Juan, Dusetti, Nelson, Mas, Eric

Publikováno v: EBioMedicine, Vol 71, Iss, Pp 103541-(2021)
EBioMedicine
EBioMedicine, Elsevier, 2021, 71, pp.103541. ⟨10.1016/j.ebiom.2021.103541⟩
EBioMedicine, 2021, 71, pp.103541. ⟨10.1016/j.ebiom.2021.103541⟩

International audience; Background: Pancreatic ductal adenocarcinoma (PDAC) is characterized by an important heterogeneity, reflected by different clinical outcomes and chemoresistance. During carcinogenesis, tumor cells display aberrant glycosylated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4da26bf3124022e8551a5d9ca7d69731
http://www.sciencedirect.com/science/article/pii/S2352396421003340

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Deciphering the Crosstalk Between Myeloid-Derived Suppressor Cells and Regulatory T Cells in Pancreatic Ductal Adenocarcinoma

Autor: Siret, Carole, Collignon, Aurelie, Silvy, Françoise, Robert, Stéphane, Cheyrol, Thierry, André, Perrine, Rigot, Véronique, Iovanna, Juan, Van De Pavert, Serge, Lombardo, Dominique, MAS, Eric, Martirosyan, Anna

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2020, 10, pp.3070. ⟨10.3389/fimmu.2019.03070⟩
Frontiers in Immunology, Vol 10 (2020)
Frontiers in Immunology, 2020, 10, pp.3070. ⟨10.3389/fimmu.2019.03070⟩

International audience; Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease with rising incidence and a remarkable resistance to current therapies. The reasons for this therapeutic failure include the tumor's extensive infiltration by immunosu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::49934c6969df890437e8b779aec302d1
https://www.hal.inserm.fr/inserm-02496718

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Akademický článek

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Expression of truncated bile salt-dependent lipase variant in pancreatic pre-neoplastic lesions

Autor: Martinez, Emmanuelle, Crenon, Isabelle, Silvy, Françoise, del Grande, Jean, Mougel, Alice, Barea, Dolores, Fina, Frederic, Bernard, Jean-Paul, Ouaissi, Mehdi, Lombardo, Dominique, Mas, Eric

Publikováno v: Oncotarget
Oncotarget, Impact journals, 2016, 8 (1), pp.536'551. ⟨10.18632/oncotarget.11777⟩

International audience; Pancreatic adenocarcinoma (PDAC) is a dismal disease. The lack of specific symptoms still leads to a delay in diagnosis followed by death within months for most patients. Exon 11 of the bile salt-dependent lipase (BSDL) gene e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6b93918a9c444bf175a0feec2643ddd8
http://europepmc.org/articles/PMC5352176

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Akademický článek

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Akademický článek

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A squalamine derivative, NV669, as a novel PTP1B inhibitor: in vitro and in vivo effects on pancreatic and hepatic tumor growth

Autor: Carmona, Sylvie, Brunel, Jean-Michel, Bonier, Renaté, Sbarra, Véronique, Robert, Stéphane, Borentain, Patrick, Lombardo, Dominique, Mas, Eric, Gerolami, René, Bonier, R�nat�, Sbarra, V�ronique, Robert, St�phane, Gerolami, Ren�

Publikováno v: Oncotarget
Oncotarget, Impact journals, 2019, 10 (62), pp.6651-6667. ⟨10.18632/oncotarget.27286⟩
Oncotarget, Impact journals, 2019, 10 (62), ⟨10.18632/oncotarget.27286⟩
Oncotarget, Impact journals, 2019, 10, pp.6651-6667
Oncotarget, 2019, 10 (62), pp.6651-6667. ⟨10.18632/oncotarget.27286⟩
Oncotarget, 2019, 10, pp.6651-6667

International audience; NV669 is an aminosterol derived from squalamine found to possess strong anticancer effects. The aim of this study was to investigate NV669's beneficial effects on human pancreatic and hepatic cancer models and to decipher the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada9fe468dc01f30e26baa7a893f0b31
https://hal.archives-ouvertes.fr/hal-02513459

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