Výsledky vyhledávání

Dysregulation of peripheral expression of the YWHA genes during conversion to psychosis

Autor: Demars, Fanny, Kebir, Oussama, Marzo, Aude, Iftimovici, Anton, Schramm, Catherine, Krebs, Marie-Odile, Chaumette, Boris

Publikováno v: Scientific Reports
Scientific Reports, 2020, 10 (1), pp.9863. ⟨10.1038/s41598-020-66901-1⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.9863. ⟨10.1038/s41598-020-66901-1⟩

International audience; The seven human 14-3-3 proteins are encoded by the YWHA-gene family. They are expressed in the brain where they play multiple roles including the modulation of synaptic plasticity and neuronal development. Previous studies hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::10fcc7eeca7ab204923edda9e5a013c0
https://www.hal.inserm.fr/inserm-02881451/document

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Wnt Signaling Mediates LTP-Dependent Spine Plasticity and AMPAR Localization through Frizzled-7 Receptors

Autor: McLeod, Faye, Bossio, Alessandro, Marzo, Aude, Ciani, Lorenza, Sibilla, Sara, Hannan, Saad, Wilson, Gemma A., Palomer, Ernest, Smart, Trevor G., Gibb, Alasdair, Salinas, Patricia C.

Publikováno v: Cell Reports, Vol 23, Iss 4, Pp 1060-1071 (2018)
Cell Reports

Summary The structural and functional plasticity of synapses is critical for learning and memory. Long-term potentiation (LTP) induction promotes spine growth and AMPAR accumulation at excitatory synapses, leading to increased synaptic strength. Glut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1dd9906c9f1fedc13615c1faba2c230c
http://www.sciencedirect.com/science/article/pii/S2211124718304959

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Akademický článek

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Evaluation of Synapse Density in Hippocampal Rodent Brain Slices

Autor: McLeod, Faye, Marzo, Aude, Podpolny, Marina, Galli, Soledad, Salinas, Patricia

Publikováno v: Journal of Visualized Experiments : JoVE

In the brain, synapses are specialized junctions between neurons, determining the strength and spread of neuronal signaling. The number of synapses is tightly regulated during development and neuronal maturation. Importantly, deficits in synapse numb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb62870f5ab9b93a9dd70f803d197d0
https://doi.org/10.3791/56153-v

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Wnt signalling tunes neurotransmitter release by directly targeting Synaptotagmin-1

Autor: Ciani, Lorenza, Marzo, Aude, Boyle, Kieran, Stamatakou, Eleanna, Lopes, Douglas M., Anane, Derek, McLeod, Faye, Rosso, Silvana Beatriz, Gibb, Alasdair, Salinas, Patricia C.

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

The functional assembly of the synaptic release machinery is well understood; however, how signalling factors modulate this process remains unknown. Recent studies suggest that Wnts play a role in presynaptic function. To examine the mechanisms invol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2f70c5220d39061f6444f86c577f8e4b
http://www.nature.com/articles/ncomms9302

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