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pro vyhledávání: '"Marzluff, W F"'
Metazoan replication-dependent histone mRNAs are the only known eukaryotic mRNAs that lack a poly(A) tail, ending instead in a conserved stem–loop sequence, which is bound to the stem–loop binding protein (SLBP) on the histone mRNP. Histone mRNAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6d647ab09aae9555756029e93230dae
Autor:
Rhoads, R. E., Darzynkiewicz, E., Su, W., Ziemniak, M., Kowalska, J., Slevin, M. K., Jemielity, J., Slepenkov, S. V., Lyons, S. M., Marzluff, W. F.
Metazoan replication-dependent histone mRNAs are only present in S-phase, due partly to changes in their stability. These mRNAs end in a unique stem–loop (SL) that is required for both translation and cell-cycle regulation. Previous studies showed
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https://explore.openaire.eu/search/publication?articleId=doi_________::3937765001d9bd027c7817979bf72909
Autor:
Sharpless, N. E., Slevin, M. K., Liu, J., Sorrentino, J. A., Burd, C. E., Marzluff, W. F., Jeck, W. R., Wang, K.
Circular RNAs composed of exonic sequence have been described in a small number of genes. Thought to result from splicing errors, circular RNA species possess no known function. To delineate the universe of endogenous circular RNAs, we performed high
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https://explore.openaire.eu/search/publication?articleId=doi_________::bc4600270dbfdfc8bf63642d507e676c
Autor:
Waltenspiel, B., Marzluff, W. F., Wagner, E. J., Chen, J., Ezzeddine, N., Albrecht, T. R., Warren, W. D.
Formation of the 3′ end of RNA polymerase II–transcribed snRNAs requires a poorly understood group of proteins called the Integrator complex. Here we used a fluorescence-based read-through reporter that expresses GFP in response to snRNA misproce
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https://explore.openaire.eu/search/publication?articleId=doi_________::f9efa9a0a63c9bad9f8560b94d79c89a
Autor:
Marzluff, W. F., Dadlez, M., Debski, J., Kaus-Drobek, M., Sabath, I., Yang, X.-C., Dominski, Z.
Animal replication-dependent histone pre-mRNAs are processed at the 3′ end by endonucleolytic cleavage that is not followed by polyadenylation. The cleavage reaction is catalyzed by CPSF73 and depends on the U7 snRNP and its integral component, Lsm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e348274f5fa54779d32fa53d24120dc4
Autor:
Marzluff, W. F.
The 3′ ends of two large noncoding RNAs, MALAT1 (metastasis-associated lung adenocarcinoma transcript 1) and MEN β, are formed by cleavage by RNase P and are capped but not polyadenylated. In the November 1, 2012, issue of Genes & Development, Wil
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https://explore.openaire.eu/search/publication?articleId=doi_________::d02d71170429635575d0b03afe15aa78
Autor:
Salzler, H. R., Dominski, Z., Marzluff, W. F., Burch, B. D., Duronio, R. J., Godfrey, A. C., Gasdaska, P. Y.
Metazoan replication-dependent histone mRNAs are the only nonpolyadenylated cellular mRNAs. Formation of the histone mRNA 3′ end requires the U7 snRNP, which contains Lsm10 and Lsm11, and FLASH, a processing factor that binds Lsm11. Here, we identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7417d9939e3fbbb8ed2dc93da5795ec
Autor:
Waltenspiel, B., Ezzeddine, N., Albrecht, T., Warren, W. D., Chen, J., Marzluff, W. F., Burch, B., Zhuo, M., Wagner, E. J.
Proper gene expression relies on a class of ubiquitously expressed, uridine-rich small nuclear RNAs (snRNAs) transcribed by RNA polymerase II (RNAPII). Vertebrate snRNAs are transcribed from a unique promoter, which is required for proper 3′-end fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cdf46b8e4d16db03398ad4aeabe3430
3′-end cleavage of histone pre-mRNAs is catalyzed by CPSF-73 and requires the interaction of two U7 snRNP-associated proteins, FLASH and Lsm11. Here, by using scanning mutagenesis we identify critical residues in human FLASH and Lsm11 that are invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e585fd0034ce89105be73826e32ef09
Autor:
Marzluff, W F, Stefanovic, B
Publikováno v:
Molecular and Cellular Biology. 12:650-660
The promoters of two U2 small nuclear RNA genes isolated from the sea urchin Lytechinus variegatus were mapped by microinjection of genes into sea urchin zygotes. One gene, LvU2E, is expressed only in oocytes and embryos and is found in a tandemly re